Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anika Bühler"'
Autor:
Nicole Groh, Anika Bühler, Chaolie Huang, Ka Wan Li, Pim van Nierop, August B. Smit, Marcus Fändrich, Frank Baumann, Della C. David
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Aging is the most important risk factor for neurodegenerative diseases associated with pathological protein aggregation such as Alzheimer’s disease. Although aging is an important player, it remains unknown which molecular changes are relevant for
Externí odkaz:
https://doaj.org/article/6922cd6cd3ef43cca1c2695e5e6e5d1e
Autor:
Lalit Kaurani, Md Rezaul Islam, Urs Heilbronner, Dennis M. Krüger, Jiayin Zhou, Aditi Methi, Judith Strauss, Ranjit Pradhan, Susanne Burkhardt, Tonatiuh Pena, Lena Erlebach, Anika Bühler, Monika Budde, Fanny Senner, Mojtaba Oraki Kohshour, Eva C. Schulte, Max Schmauß, Eva Z. Reininghaus, Georg Juckel, Deborah Kronenberg-Versteeg, Ivana Delalle, Francesca Odoardi, Alexander Flügel, Thomas G. Schulze, Peter Falkai, Farahnaz Sananbenesi, Andre Fischer
Schizophrenia is a psychiatric disorder that is still not readily treatable. Pharmaceutical advances in the treatment of schizophrenia have mainly focused on the protein coding part of the human genome. However, the vast majority of the human transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f775bc341882cae88a4596c327d4ea
https://doi.org/10.1101/2023.03.21.533602
https://doi.org/10.1101/2023.03.21.533602
Autor:
Matthias Flötenmeyer, Anika Bühler, Ulrike Obermüller, Mathias Jucker, Matthias Staufenbiel, Anne-Marie Marzesco, Frank Baumann
Publikováno v:
Scientific reports 6(1), 28125 (2016). doi:10.1038/srep28125
Scientific Reports
Scientific Reports
An early event in Alzheimer’s disease (AD) pathogenesis is the formation of extracellular aggregates of amyloid-β peptide (Aβ), thought to be initiated by a prion-like seeding mechanism. However, the molecular nature and location of the Aβ seeds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f19f18ef3c9df344b7096b3e56de53
https://pub.dzne.de/record/138971
https://pub.dzne.de/record/138971
Autor:
Lary C. Walker, Jasmin Mahler, Mathias Jucker, Manuela Neumann, K. Peter R. Nilsson, Amarallys F. Cintron, Sarah K. Fritschi, Per Hammarström, Anika Bühler, Lan Ye, Frank Baumann
Publikováno v:
Acta neuropathologica 128(4), 477-484 (2014). doi:10.1007/s00401-014-1339-2
Cerebral β-amyloidosis can be exogenously induced by the intracerebral injection of brain extracts containing aggregated β-amyloid (Aβ) into young, pre-depositing Aβ precursor protein- (APP) transgenic mice. Previous work has shown that the induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0efb8ca8ebc44dd5ce70616b1d5326
https://pub.dzne.de/record/137547
https://pub.dzne.de/record/137547
Autor:
Frank Baumann, Amudha Nagarathinam, Claudia Schäfer, Mathias Jucker, Matthias Staufenbiel, Martin Jeffrey, Gillian McGovern, Philip Höflinger, Anika Bühler
Publikováno v:
The journal of neuroscience 33(49), 19284-19294 (2013). doi:10.1523/JNEUROSCI.2542-13.2013
Pathological, genetic, and biochemical hallmarks of Alzheimer's disease (AD) are linked to amyloid-β (Aβ) peptide aggregation. Especially misfolded Aβ42peptide is sufficient to promote amyloid plaque formation. However, the cellular compartment fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cec95c7a11bc23718cf664c8e13cec5