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6b,11b-Dihydroxy-6b,11b-dihydro-7H-indeno[1,2-b]naphtho[2,1-d]furan-7-one (DHFO), a small molecule targeting NF-κB, demonstrates therapeutic potential in immunopathogenic chronic inflammatory conditions

Autor: Geetha Mathew, Ega Durgashivaprasad, Neetinkumar D. Reddy, Anija Jacob, Mazhuvancherry Kesavan Unnikrishnan

Publikováno v: International immunopharmacology. 15(1)

6b,11b-Dihydroxy-6b,11b-dihydro-7H-indeno[1,2-b]naphtho[2,1-d]furan-7-one (DHFO), an easily synthesisable, orally bioavailable and relatively non-toxic small molecule synthesised in our lab, was previously reported to possess anti-oxidant, 5-lipoxyge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b057cdd0cfa3bf968aa45e78ce9f6fd
https://pubmed.ncbi.nlm.nih.gov/23159605

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