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Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline
Autor:
Saher Sue Hammoud, Aniela Crayton, Jacqueline Graniel, Peedikayil E. Thomas, Leolene J Carrington, Catherine E. Keegan, Joshua D Brandstadter, Jayakrishnan Nandakumar, Adrienne Niederriter Shami, James J. White, Kamlesh Bisht, Alina Moroz, Jennifer Chase, Frederick Allen, Ann Friedman, Eric Perkey, Ivan Maillard, Anna Mychalowych, Mariel Manzor, Ashley Vanderbeck
Publikováno v:
Life Science Alliance
A TPP1 mutation known to cause telomere shortening and bone marrow failure in humans recapitulates telomere loss but results in severe germline defects in mice without impacting murine hematopoiesis.
Telomerase extends chromosome ends in somatic
Telomerase extends chromosome ends in somatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f399ba0af60580eccc81bcad6af3e0
https://doi.org/10.1101/2021.07.29.454392
https://doi.org/10.1101/2021.07.29.454392
