Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anibal R. Melgarejo"'
Autor:
Stephen Hyslop, Alessandra Stroka, Valéria Barbosa de Souza, Bruna R. Inoue, Anibal R. Melgarejo, Frank Denis Torres-Huaco, Lourdes Dias, André L. Rennó, Mariana Agustinho Rodrigues, Norma C. Sousa, Renata Lopes Rodrigues
Publikováno v:
Toxicon. 123:25-44
In this work, we examined some mechanisms involved in the hypotension caused by Lachesis muta (South American bushmaster) venom in anesthetized rats. Venom (1.5 mg/kg, i.v.) caused immediate hypotension that was maximal after 5 min and gradually retu
Autor:
Salvatore G. De-Simone, Anibal R. Melgarejo, Jorge L.S. Pina, David W. Provance, Hilton Jorge Nascimento, Aniesse S. Aguiar, Patricia Fernandes Ferreira, Isis C. Prado
Publikováno v:
Analytical biochemistry.
The availability of purified antibodies is a prerequisite for many applications and the appropriate choice(s) for antibody-purification is crucial. Numerous methods have been developed for the purification of antibodies from different sources with af
Autor:
Salvatore Giovanni De-Simone, Aniesse S. Aguiar, Luiz A.L. Teixeira-Pinto, Jonathas D.L. Santos, Paloma Napoleão-Pego, Anibal R. Melgarejo, Thatiane S. De-Simone, Daniela P. Marchi-Salvador
Publikováno v:
Toxicon. 72:90-101
The benefits from treatment with antivenom sera are indubitable. However, the mechanism for toxin neutralization has not been completely elucidated. A mixture of anti-bothropic and anti-crotalic horse antivenom has been reported to be more effective
Autor:
Alessandra Stroka, Bruna R. Inoue, André L. Rennó, Stephen Hyslop, Mariana Agustinho Rodrigues, Patricia Costa Panunto, Lourdes Dias, Anibal R. Melgarejo
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 123
In this work, we examined the hemodynamic responses to Lachesis muta (South American bushmaster) venom in anesthetized male Wistar rats. Venom (1.5 mg/kg, i.v.) caused immediate hypotension that was followed by a gradual return towards baseline over
Autor:
Salvatore G, De-Simone, Paloma, Napoleão-Pego, Luiz A L, Teixeira-Pinto, Jonathas D L, Santos, Thatiane S, De-Simone, Anibal R, Melgarejo, Aniesse S, Aguiar, Daniela P, Marchi-Salvador
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 72
The benefits from treatment with antivenom sera are indubitable. However, the mechanism for toxin neutralization has not been completely elucidated. A mixture of anti-bothropic and anti-crotalic horse antivenom has been reported to be more effective
Autor:
Aniesse S. Aguiar, Debora Foguel, Carlos Corrêa-Netto, Salvatore Giovanni De-Simone, Ricardo Teixeira-Araujo, Márcia Regina Soares, Russolina B. Zingali, Anibal R. Melgarejo
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 55(7)
A combination of anti-bothropic and anti-crotalic sera has been reported to be more effective in neutralizing the effects of Bothrops jararacussu venom than anti-bothropic serum alone. The role of proteins from B. jararacussu venom in the horse immun
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 36(5)
Pharmacological aspects of mouse hind-paw oedema induced by subplantar injections of Lachesis muta rhombeata (LMR) venom were investigated. The oedema induced by subplantar injections of 10 to 50 ng/g of LMR venom is dose dependent, with onset, peak
Autor:
Aniesse S. Aguiar, Paloma Napoleão-Pêgo, Salvatore G. De-Simone, Anibal R. Melgarejo, Luiz A.L. Teixeira-Pinto, David W. Provance
Publikováno v:
Toxicon. :83-93
The presence of whole horse IgG in therapeutic snake antivenom preparations of high purity is a contamination that can cause IgE-mediated allergic reactions in patients. In this study, the immunodominant IgE and IgG-binding epitopes in horse heavy ch