Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Ani Solanki"'
Autor:
Michael J. V. White, Melis Ozkan, Jorge Emiliano Gomez-Medellin, Michal M. Rączy, Kyle M. Koss, Ani Solanki, Zheng Jenny Zhang, Aaron T. Alpar, Bilal A. Naved, Jason Wertheim, Jeffrey A. Hubbell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Fibrosis is involved in 45% of deaths in the United States, and no treatment exists to reverse the progression of lung or kidney fibrosis. Myofibroblasts are key to the progression and maintenance of fibrosis. We investigated features of cel
Externí odkaz:
https://doaj.org/article/f97277bb22ed485abe8d738c965ae2af
Autor:
Britteny J. Cassaidy, Brittany A. Moser, Ani Solanki, Qing Chen, Jingjing Shen, Kristen Gotsis, Zoe Lockhart, Nakisha Rutledge, Matthew G. Rosenberger, Yixiao Dong, Delaney Davis, Aaron P. Esser- Kahn
Publikováno v:
ACS Omega, Vol 9, Iss 10, Pp 11608-11614 (2024)
Externí odkaz:
https://doaj.org/article/74c56abe02dd419dad7e8087a39816a4
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract The biomaterial fibrin is widely used as a clinical tissue sealant in surgery. In preclinical research, fibrin is also extensively studied as a carrier material for growth factor delivery. In these applications, premature fibrin degradation
Externí odkaz:
https://doaj.org/article/735cb2120e384debbb2fc2348f4495cc
Autor:
Lisa R. Volpatti, Rachel P. Wallace, Shijie Cao, Michal M. Raczy, Ruyi Wang, Laura T. Gray, Aaron T. Alpar, Priscilla S. Briquez, Nikolaos Mitrousis, Tiffany M. Marchell, Maria Stella Sasso, Mindy Nguyen, Aslan Mansurov, Erica Budina, Ani Solanki, Elyse A. Watkins, Mathew R. Schnorenberg, Andrew C. Tremain, Joseph W. Reda, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Shann S. Yu, Balaji Manicassamy, James L. LaBelle, Matthew V. Tirrell, Glenn Randall, Marcin Kwissa, Melody A. Swartz, Jeffrey A. Hubbell
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1368-1380 (2021)
Externí odkaz:
https://doaj.org/article/7d6f01c438c547eb843b88a5c03b6825
Autor:
Kiranj Chaudagar, Hanna M. Hieromnimon, Rimpi Khurana, Brian Labadie, Taghreed Hirz, Shenglin Mei, Raisa Hasan, Jordan Shafran, Anne Kelley, Eva Apostolov, Ghamdan Al-Eryani, Kate Harvey, Srikrishnan Rameshbabu, Mayme Loyd, Kaela Bynoe, Catherine Drovetsky, Ani Solanki, Erica Markiewicz, Marta Zamora, Xiaobing Fan, Stephan Schürer, Alex Swarbrick, David B. Sykes, Akash Patnaik
Publikováno v:
Clinical Cancer Research. 29:1952-1968
Purpose: Phosphatase and tensin homolog (PTEN) loss of function occurs in approximately 50% of patients with metastatic castrate-resistant prostate cancer (mCRPC), and is associated with poor prognosis and responsiveness to standard-of-care therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be68d3800b4a39cbb166c623f9acb33
https://doi.org/10.1158/1078-0432.ccr-22-3350
https://doi.org/10.1158/1078-0432.ccr-22-3350
Autor:
Karim Ullah, Yan Li, Qiaoshan Lin, Kaichao Pan, Tu Nguyen, Ani Solanki, Qiaozhu Su, Willard Willard Sharp, Rongxue Wu
Publikováno v:
Ullah, K, Li, Y, Lin, Q, Pan, K, Nguyen, T, Aniruddhsingh, S, Su, Q, Sharp, W, Wu, R & Metzinger, L (ed.) 2023, ' Comparative analysis of whole transcriptome profiles in septic cardiomyopathy: insights from CLP-and LPS-induced mouse models ', Genes, vol. 14, no. 7, 1366 . https://doi.org/10.3390/genes14071366
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, with septic cardiomyopathy being a common and severe complication. Despite its significant clinical impact, the molecular mechanisms underlying sepsis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db5d77b1c0ab02cb9bdf48846685bc7
https://pure.qub.ac.uk/en/publications/8b9482c2-1fa5-4ce0-9807-e8ebe4d3c77e
https://pure.qub.ac.uk/en/publications/8b9482c2-1fa5-4ce0-9807-e8ebe4d3c77e
Autor:
Shijie Cao, Erica Budina, Michal M. Raczy, Ani Solanki, Mindy Nguyen, Kevin Hultgren, Phillip Ang, Joseph W. Reda, Lucas S. Shores, Ishita Pillai, Rachel P. Wallace, Arjun Dhar, Elyse A. Watkins, Jeffrey A. Hubbell
Butyrate, a metabolite produced by commensal bacteria, has been intensively studied for its immunomodulatory effects on various immune cells, including T regulatory cells, macrophages, and dendritic cells. Butyrate’s development as a drug has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77fc50ad778a74748e88ff33f6181902
https://doi.org/10.1101/2023.04.28.538720
https://doi.org/10.1101/2023.04.28.538720
Autor:
Rachel P. Wallace, Kirsten C. Refvik, Jennifer T. Antane, Kym Brünggel, Andrew C. Tremain, Michal R. Raczy, Aaron T. Alpar, Mindy Nguyen, Ani Solanki, Anna J. Slezak, Elyse A. Watkins, Abigail L. Lauterbach, Shijie Cao, D. Scott Wilson, Jeffrey A. Hubbell
Publikováno v:
bioRxiv
SummaryImmunogenic biologics trigger an anti-drug antibody (ADA) response in patients, which reduces efficacy and increases adverse reactions. Our laboratory has previously shown that targeting protein antigen to the liver microenvironment can reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027b3e25897b526905b8338f110d6e48
https://europepmc.org/articles/PMC10104138/
https://europepmc.org/articles/PMC10104138/
Autor:
Akash Patnaik, David B. Sykes, Alex Swarbrick, Stephan Schürer, Xiaobing Fan, Marta Zamora, Erica Markiewicz, Ani Solanki, Catherine Drovetsky, Kaela Bynoe, Mayme Loyd, Srikrishnan Rameshbabu, Kate Harvey, Ghamdan Al-Eryani, Eva Apostolov, Anne Kelley, Jordan Shafran, Raisa Hasan, Shenglin Mei, Taghreed Hirz, Brian Labadie, Rimpi Khurana, Hanna M. Hieromnimon, Kiranj Chaudagar
Purpose:Phosphatase and tensin homolog (PTEN) loss of function occurs in approximately 50% of patients with metastatic castrate-resistant prostate cancer (mCRPC), and is associated with poor prognosis and responsiveness to standard-of-care therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cabfb09a9cb30f9f1e328f0b008a53c6
https://doi.org/10.1158/1078-0432.c.6563227.v1
https://doi.org/10.1158/1078-0432.c.6563227.v1
Autor:
Akash Patnaik, David B. Sykes, Alex Swarbrick, Stephan Schürer, Xiaobing Fan, Marta Zamora, Erica Markiewicz, Ani Solanki, Catherine Drovetsky, Kaela Bynoe, Mayme Loyd, Srikrishnan Rameshbabu, Kate Harvey, Ghamdan Al-Eryani, Eva Apostolov, Anne Kelley, Jordan Shafran, Raisa Hasan, Shenglin Mei, Taghreed Hirz, Brian Labadie, Rimpi Khurana, Hanna M. Hieromnimon, Kiranj Chaudagar
Supplementary Figure S1. The majority of Pb-Cre; PTENfl/fl Trp53fl/fl mice are de novo resistant to ADT. Supplementary Figure S2. ADT/PI3Ki combination therapy halts prostate tumor growth up to 14 days, followed by development of resistance in majori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::998c4977bf8201764c79ff7057327293
https://doi.org/10.1158/1078-0432.22551388
https://doi.org/10.1158/1078-0432.22551388