Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ani Minasyan"'
Autor:
Joshua Hakimian, Ani Minasyan, Lily Zhe-Ying, Mariana Loureiro, Austin Beltrand, Camille Johnston, Alexander Vorperian, Nicole Romaneschi, Waleed Atallah, Fernando Gomez-Pinilla, Wendy Walwyn
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175090 (2017)
Opiates, one of the oldest known drugs, are the benchmark for treating pain. Regular opioid exposure also induces euphoria making these compounds addictive and often misused, as shown by the current epidemic of opioid abuse and overdose mortalities.
Externí odkaz:
https://doaj.org/article/b05dac26dd1747869f010b6929c724a4
Autor:
Nitish Mittal, Ani Minasyan, Nicole Romaneschi, Joshua K Hakimian, Gabriel Gonzalez-Fernandez, Ralph Albert, Nina Desai, Ian A Mendez, Timothy Schallert, Sean B Ostlund, Wendy Walwyn
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185796 (2017)
The two highly homologous non-visual arrestins, beta-arrestin 1 and 2, are ubiquitously expressed in the central nervous system, yet knowledge of their disparate roles is limited. While beta-arrestin 2 (βarr2) has been implicated in several aspects
Externí odkaz:
https://doaj.org/article/dbe5aa40addc49c08359554843f5cb34
Autor:
Nitish Mittal, Kristofer Roberts, Katsuri Pal, Laurent A. Bentolila, Elissa Fultz, Ani Minasyan, Catherine Cahill, Amynah Pradhan, David Conner, Kathryn DeFea, Christopher Evans, Wendy Walwyn
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 1010-1021 (2013)
G-protein-coupled receptors (GPCRs) are typically present in a basal, inactive state but, when bound to an agonist, activate downstream signaling cascades. In studying arrestin regulation of opioid receptors in dorsal root ganglia (DRG) neurons, we f
Externí odkaz:
https://doaj.org/article/b87b430e3e534646b21952c2b3e15e0a
Autor:
Suchi Tiwari, Ralph Albert, Anna M.W. Taylor, Ani Minasyan, Joshua K. Hakimian, Nicole Romaneschi, Catherine M. Cahill, Wendy Walwyn, Nitish Mittal, Alex Lee, Camille Johnston, Amie L. Severino, Christopher J. Evans, Carlos Torres, Brigitte L. Kieffer, Nathanial Velarde, Claire Gaveriaux-Ruff
Publikováno v:
eNeuro
eNeuro, 2020, 7 (5), pp.0146-20. ⟨10.1523/ENEURO.0146-20.2020⟩
eNeuro, vol 7, iss 5
eNeuro, 2020, 7 (5), pp.0146-20. ⟨10.1523/ENEURO.0146-20.2020⟩
eNeuro, vol 7, iss 5
μ-Opioid receptors (MORs) are densely expressed in different brain regions known to mediate reward. One such region is the striatum where MORs are densely expressed, yet the role of these MOR populations in modulating reward is relatively unknown. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4499cdae59ee8841a7bb87ed6ca90f13
https://hal.science/hal-03669760/file/islandora_151108.pdf
https://hal.science/hal-03669760/file/islandora_151108.pdf
Autor:
Helena S. Ennes, Wendy Walwyn, James A. McRoberts, Wenling Chen, Juan Carlos G. Marvizón, Ani Minasyan, Hyeyoung Kim
Publikováno v:
The Journal of Neuroscience. 36:204-221
Many chronic pain disorders alternate between bouts of pain and periods of remission. The latent sensitization model reproduces this in rodents by showing that the apparent recovery (“remission”) from inflammatory or neuropathic pain can be rever
Autor:
Viola Y. Quach, Ani Minasyan, Andrew Jann, Yin-Ying Lin, Jesse D. Cushman, Michael Cheng, Ganeev Singh, Wendy Walwyn, Joshua K. Hakimian, Michelle Monroe, Robel Dagnew, Jerikko Agatep, Theodore Kee
Publikováno v:
Neurophotonics. 4(4)
The use of optogenetics to activate or inhibit neurons is an important toolbox for neuroscientists. Several optogenetic devices are in use. These range from wired systems where the optoprobe is physically connected to the light source by a tether, to
Autor:
Camille Johnston, Ani Minasyan, Nicole Romaneschi, Joshua K. Hakimian, Fernando Gomez-Pinilla, Waleed Atallah, Wendy Walwyn, Alexander Vorperian, Austin Beltrand, Mariana Loureiro, Lily Zhe-Ying
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0175090 (2017)
PLoS ONE, Vol 12, Iss 4, p e0175090 (2017)
Opiates, one of the oldest known drugs, are the benchmark for treating pain. Regular opioid exposure also induces euphoria making these compounds addictive and often misused, as shown by the current epidemic of opioid abuse and overdose mortalities.
Autor:
Wendy Walwyn, Ian A. Mendez, Joshua K. Hakimian, Nitish Mittal, Sean B. Ostlund, Timothy J Schallert, Ralph Albert, Ani Minasyan, Gabriel Gonzalez-Fernandez, Nina Desai, Nicole Romaneschi
Publikováno v:
Mittal, Nitish; Minasyan, Ani; Romaneschi, Nicole; Hakimian, Joshua K; Gonzalez-Fernandez, Gabriel; Albert, Ralph; et al.(2017). Beta-arrestin 1 regulation of reward-motivated behaviors and glutamatergic function.. PloS one, 12(10), e0185796. doi: 10.1371/journal.pone.0185796. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/26x372n0
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0185796 (2017)
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0185796 (2017)
The two highly homologous non-visual arrestins, beta-arrestin 1 and 2, are ubiquitously expressed in the central nervous system, yet knowledge of their disparate roles is limited. While beta-arrestin 2 (βarr2) has been implicated in several aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f8799fa292b712ceaab25f1b871c1f
http://www.escholarship.org/uc/item/26x372n0
http://www.escholarship.org/uc/item/26x372n0
Publikováno v:
Current Protocols in Neuroscience
Latent sensitization is a rodent model of chronic pain that reproduces both its episodic nature and its sensitivity to stress. It is triggered by a wide variety of injuries ranging from injection of inflammatory agents to nerve damage. It follows a c
Autor:
Lauren Heimbigner, Ani Minasyan, Gabriel Gonzalez-Fernandez, Matthew Hur, Jonathan W. McKinley, Wendy Walwyn, Granville P. Storey, Ian J. Bamford, Nigel S. Bamford
Publikováno v:
eneuro. 3:ENEURO.0095-15.2015
Corticostriatal signaling participates in sensitized responses to drugs of abuse, where short-term increases in dopamine availability provoke persistent, yet reversible, changes in glutamate release. Prior studies in mice show that amphetamine withdr