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Autor:
Keith Ramig, Kitae Kwon, Sasan Karimi, Allen Ko, Edyta M. Greer, Aaron Lam, Leyla Cavdar, Lukasz Bogdan, Ani Coaderaj, Gopal Subramaniam, David J. Szalda, Jeffrey Li
Publikováno v:
The Journal of organic chemistry. 81(8)
A series of 2,4-disubstituted 1H-1-benzazepines, 2a-d, 4, and 6, were studied, varying both the substituents at C2 and C4 and at the nitrogen atom. The conformational inversion (ring-flip) and nitrogen-atom inversion (N-inversion) energetics were stu