Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ani, Michaud"'
Autor:
Jacob L. Capener, James D. Vasta, Vittorio L. Katis, Ani Michaud, Michael T. Beck, Sabrina C. D. Daglish, Sarit Cohen-Kedar, Efrat Shaham Barda, Stefanie Howell, Iris Dotan, Matthew B. Robers, Alison D. Axtman, Frances M. Bashore
Publikováno v:
Frontiers in Chemical Biology, Vol 3 (2024)
Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase that is activated by phosphorylation events downstream of FcR, B-cell and T-cell receptors, integrins, and C-type lectin receptors. When the tandem Src homology 2 (SH2) domains of SYK bin
Externí odkaz:
https://doaj.org/article/5b14e25fb79449cd9a67529c673d86a8
Autor:
Xuan Yang, Jeffery L. Smith, Michael T. Beck, Jennifer M. Wilkinson, Ani Michaud, James D. Vasta, Matthew B. Robers, Timothy M. Willson
Publikováno v:
Molecules, Vol 28, Iss 7, p 2950 (2023)
PLK1 is a protein kinase that regulates mitosis and is both an important oncology drug target and a potential antitarget of drugs for the DNA damage response pathway or anti-infective host kinases. To expand the range of live cell NanoBRET target eng
Externí odkaz:
https://doaj.org/article/d38f4c63c4d142138e67e669810bc196
Autor:
James Vasta, Ani Michaud, Chad Zimprich, Morgan Thomas, Jennifer Wilkinson, J. Aaron Crapster, Matthew Robers
RAF dimer inhibitors offer therapeutic potential in RAF- and RAS-driven cancers. The utility of such drugs is predicated on their capacity to occupy both RAF protomers in the RAS-RAF signaling complex. Here we describe a method to conditionally quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54bdb971ffe29497abcef42744b9e186
https://doi.org/10.21203/rs.3.rs-2175742/v1
https://doi.org/10.21203/rs.3.rs-2175742/v1
Autor:
Jennifer Landino, Marcin Leda, Ani Michaud, Zachary T. Swider, Mariah Prom, Christine M. Field, William M. Bement, Anthony Vecchiarelli, Andrew B. Goryachev, Ann L. Miller
Publikováno v:
Biophysical Journal. 122:167a-168a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a533cfa66fd5cbf838a3fc684a37daee
https://doi.org/10.1016/j.bpj.2022.11.1053
https://doi.org/10.1016/j.bpj.2022.11.1053
Autor:
Zachary T. Swider, Ann L. Miller, George von Dassow, Ani Michaud, Andrew B. Goryachev, William M. Bement, Marcin Leda, Jennifer Landino
Publikováno v:
Curr Biol
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
Michaud, A, Swider, Z T, Landino, J, Leda, M, Miller, A L, von Dassow, G, Goryachev, A B & Bement, W M 2021, ' Cortical excitability and cell division ', Current Biology, vol. 31, no. 10, pp. PR553-R559 . https://doi.org/10.1016/j.cub.2021.02.053
As the interface between the cell and its environment, the cell cortex must be able to respond to a variety of external stimuli. This is made possible in part by cortical excitability, a behavior driven by coupled positive and negative feedback loops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc12fae112c84f59580367eb4d1feaee
https://doi.org/10.1016/j.cub.2021.02.053
https://doi.org/10.1016/j.cub.2021.02.053
Autor:
Ani Michaud, Marcin Leda, Zachary T. Swider, Songeun Kim, Jiaye He, Jennifer Landino, Jenna R. Valley, Jan Huisken, Andrew B. Goryachev, George von Dassow, William M. Bement
Publikováno v:
Michaud, A, Leda, M, Swider, Z T, Kim, S, He, J, Landino, J, Valley, J R, Huisken, J, Goryachev, A B, von Dassow, G & Bement, W M 2022, ' A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2 and RGA-3/4 ', Journal of Cell Biology, vol. 221, no. 8, e202203017 . https://doi.org/10.1083/jcb.202203017
Many cells can generate complementary traveling waves of actin filaments (F-actin) and cytoskeletal regulators. This phenomenon, termed cortical excitability, results from coupled positive and negative feedback loops of cytoskeletal regulators. The n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9b7bae8d5f417516ef7569b70c78e1
https://doi.org/10.1083/jcb.202203017
https://doi.org/10.1083/jcb.202203017
Autor:
Zachary T, Swider, Ani, Michaud, Marcin, Leda, Jennifer, Landino, Andrew B, Goryachev, William M, Bement
Publikováno v:
Molecular biology of the cell. 33(8)
Interest in cortical excitability-the ability of the cell cortex to generate traveling waves of protein activity-has grown considerably over the past 20 years. Attributing biological functions to cortical excitability requires an understanding of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c807c85c5b52fc5ca2bf86b62645a8d2
https://pubmed.ncbi.nlm.nih.gov/35594176
https://pubmed.ncbi.nlm.nih.gov/35594176
Autor:
Ani Michaud, Marcin Leda, Zachary T. Swider, Songeun Kim, Jiaye He, Jennifer Landino, Jenna R. Valley, Jan Huisken, Andrew B. Goryachev, George von Dassow, William Bement
Many cells can generate complementary traveling waves of actin filaments (F-actin) and cytoskeletal regulators. This phenomenon, termed cortical excitability, results from coupled positive and negative feedback loops of cytoskeletal regulators. The n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4f6d3b71c777231a6be2d00d7af94e
https://doi.org/10.1101/2022.03.08.483353
https://doi.org/10.1101/2022.03.08.483353
Autor:
Zachary T Swider, Ani Michaud, Marcin Leda, Jennifer Landino, Andrew B. Goryachev, William M. Bement
Publikováno v:
Swider, Z T, Michaud, A, Leda, M, Landino, J, Goryachev, A B & Bement, W M 2022, ' Cell cycle and developmental control of cortical excitability in Xenopus laevis ', Molecular Biology of the Cell, vol. 33, no. 8 . https://doi.org/10.1091/mbc.E22-01-0025
Interest in cortical excitability – the ability of the cell cortex to generate traveling waves of protein activity – has grown considerably over the past twenty years. Attributing biological functions to cortical excitability requires an understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a762a2e7790b445bdef0511ed8ac381
https://doi.org/10.1101/2022.02.11.480124
https://doi.org/10.1101/2022.02.11.480124
Autor:
Ann L. Miller, Andrew B. Goryachev, Christine M. Field, Ani Michaud, William M. Bement, Mariah J. Prom, Marcin Leda, Anthony G. Vecchiarelli, Zachary T. Swider, Jennifer Landino
Publikováno v:
Landino, J, Leda, M, Michaud, A, Swider, Z T, Prom, M, Field, C M, Bement, W M, Vecchiarelli, A G, Goryachev, A B & Miller, A L 2021, ' Rho and F-actin self-organize within an artificial cell cortex ', Current Biology, vol. 31, no. 24, pp. P5613-5621.E5 . https://doi.org/10.1016/j.cub.2021.10.021
Curr Biol
Curr Biol
SummaryThe cell cortex, comprised of the plasma membrane and underlying cytoskeleton, undergoes dynamic reorganizations during a variety of essential biological processes including cell adhesion, cell migration, and cell division1,2. During cell divi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcd3a5eef8c2b63d1dddedbf9a20cc3
https://doi.org/10.1016/j.cub.2021.10.021
https://doi.org/10.1016/j.cub.2021.10.021