Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Anh T Le"'
Publikováno v:
Гений oртопедии, Vol 30, Iss 5, Pp 644-650 (2024)
Introduction Avascular necrosis of the femoral head (ANFH) is a phenomenon vascular supply disruption lead to death of bone cells around the femoral head. The disease is a severe health issue all over the world. Within 2 years about 80 % to 85 % of
Externí odkaz:
https://doaj.org/article/096650e707ec42fcabf29a3aceab8e18
Publikováno v:
Frontiers in Environmental Science, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/c0fa27d21861470b8b8ef4b509ba5a3d
Autor:
Kurtis D Davies, Sakshi Mahale, David P Astling, Dara L Aisner, Anh T Le, Trista K Hinz, Aria Vaishnavi, Paul A Bunn, Lynn E Heasley, Aik-Choon Tan, D Ross Camidge, Marileila Varella-Garcia, Robert C Doebele
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82236 (2013)
The targeting of oncogenic 'driver' kinases with small molecule inhibitors has proven to be a highly effective therapeutic strategy in selected non-small cell lung cancer (NSCLC) patients. However, acquired resistance to targeted therapies invariably
Externí odkaz:
https://doaj.org/article/ac60de8b4c2f4279b38e26b9cd47f632
Publikováno v:
Thoracic Cancer, Vol 14, Iss 33, Pp 3259-3265 (2023)
Abstract Background The vast majority of patients with ROS1 positive non‐small cell lung cancer (NSCLC) derive clinical benefit from currently approved ROS1 therapies, including crizotinib and entrectinib. However, a small proportion of patients tr
Externí odkaz:
https://doaj.org/article/b4a49be5552c4d6ea20d58cdd6f1cf4d
Publikováno v:
Data in Brief, Vol 52, Iss , Pp 110004- (2024)
Adjuvant radiotherapy for breast cancer may involve some incidental exposure of the ipsilateral internal mammary artery to ionizing radiation. However, the relevant evidence is limited and inconsistent. The dataset presented in this article contains
Externí odkaz:
https://doaj.org/article/bd008f253a6d4f80b54f7a207a11ddd7
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e22361- (2024)
Payments for ecosystem services programs (PESPs) are increasingly being adopted globally to enhance sustainability outcomes. There are also hundreds of studies yearly on various aspects of PESPs, but research on their contributions to sustainability
Externí odkaz:
https://doaj.org/article/648166567a96473094a78d6d92154a59
Autor:
Emily K. Kleczko, Trista K. Hinz, Teresa T. Nguyen, Natalia J. Gurule, Andre Navarro, Anh T. Le, Amber M. Johnson, Jeff Kwak, Diana I. Polhac, Eric T. Clambey, Mary Weiser-Evans, Daniel T. Merrick, Michael C. Yang, Tejas Patil, Erin L. Schenk, Lynn E. Heasley, Raphael A. Nemenoff
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Lung cancers bearing oncogenic EML4-ALK fusions respond to targeted tyrosine kinase inhibitors (TKIs; e.g., alectinib), with variation in the degree of shrinkage and duration of treatment (DOT). However, factors that control this response ar
Externí odkaz:
https://doaj.org/article/8192c462eff74d50be9a1f7314bb046e
Autor:
Logan C. Tyler, Anh T. Le, Nan Chen, Hala Nijmeh, Liming Bao, Timothy R. Wilson, David Chen, Brian Simmons, Kristen M. Turner, Dean Perusse, Shailaja Kasibhatla, Jason Christiansen, Arkadiusz Z. Dudek, Robert C. Doebele
Publikováno v:
Thoracic Cancer, Vol 13, Iss 21, Pp 3032-3041 (2022)
Abstract Background ROS1 tyrosine kinase inhibitors (TKIs) have demonstrated significant clinical benefit for ROS1+ NSCLC patients. However, TKI resistance inevitably develops through ROS1 kinase domain (KD) modification or another kinase driving byp
Externí odkaz:
https://doaj.org/article/69b9447303ff45faa281860090224996
Autor:
Laura Schubert, Anh T. Le, Trista K. Hinz, Andre C. Navarro, Sarah K. Nelson-Taylor, Raphael A. Nemenoff, Lynn E. Heasley, Robert C. Doebele
Publikováno v:
Biology Open, Vol 12, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/b9e7e4875d3e41e1b3b2c29b66661bcb
Autor:
Laura Schubert, Andrew Elliott, Anh T. Le, Adriana Estrada-Bernal, Robert C. Doebele, Emil Lou, Hossein Borghaei, Michael J. Demeure, Razelle Kurzrock, Joshua E. Reuss, Sai-Hong Ignatius Ou, David R. Braxton, Christian A. Thomas, Sourat Darabi, Wolfgang Michael Korn, Wafik S. El-Deiry, Stephen V. Liu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeGene fusions involving receptor tyrosine kinases (RTKs) define an important class of genomic alterations with many successful targeted therapies now approved for ALK, ROS1, RET and NTRK gene fusions. Fusions involving the ERBB family of RTKs h
Externí odkaz:
https://doaj.org/article/70a0b6cd821d4f078b9efca4a60b1301