Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anh T, Lee"'
Autor:
Howard A. Burris, Robert C. Doebele, Anh T. Lee, Nisha Nanda, Afshin Dowlati, Alice T. Shaw, Adriana Estrada-Bernal, Matthew H. Taylor, Anna F. Farago, Marcia S. Brose, Todd M. Bauer, Michael C. Cox, David S. Hong
Publikováno v:
Cancer Research. 76:CT008-CT008
Background: NTRK1, 2 and 3 gene fusions occur across a wide array of tumor types and can lead to constitutively-active TRKA, B, and C kinases. LOXO-101 is an orally bioavailable, potent, ATP-competitive, selective pan-TRK inhibitor. Here, we report r
Autor:
Robert C. Doebele, Todd M. Bauer, Afshin Dowlati, Howard A. Burris, Michael C. Cox, Anh T. Lee, Anna F. Farago, Alice T. Shaw, Jennifer A. Low, David S. Hong, Nisha Nanda, Adriana Estrada-Bernal, Marcia S. Brose
Publikováno v:
Molecular Cancer Therapeutics. 14:PR13-PR13
Background: Gene fusions involving the NTRK1, 2 and 3 genes result in constitutively-active TRKA, -B, and -C kinases that are prevalent in a wide array of tumor types, including lung adenocarcinoma, thyroid, head and neck cancer, sarcoma, and other t
Autor:
Samuel F, Huang, Sun-Jin, Kim, Anh T, Lee, Takashi, Karashima, Cora, Bucana, Daniel, Kedar, Paul, Sweeney, Badar, Mian, Dominic, Fan, David, Shepherd, Isaiah J, Fidler, Colin P, Dinney, Jerald J, Killion
Publikováno v:
Cancer research. 62(20)
We evaluated whether treatment of orthotopic human prostate cancer in nude mice with pegylated IFN-alpha-2b (PEG-IFN-alpha-2b) and docetaxel could represent a two-compartment targeting of primary tumor (tumor cells and tumor-associated endothelial ce