Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Angus K. Nightingale"'
Autor:
Ahmed El-Medany, Zoe H. Adams, Hazel C. Blythe, Katrina A. Hope, Adrian H. Kendrick, Ana Paula Abdala Sheikh, Julian F. R. Paton, Angus K. Nightingale, Emma C. Hart
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-10 (2024)
Abstract Background The symptoms of long COVID, which include fatigue, breathlessness, dysregulated breathing, and exercise intolerance, have unknown mechanisms. These symptoms are also observed in heart failure and are partially driven by increased
Externí odkaz:
https://doaj.org/article/236c1c97f455485b8a53adfd42f438cb
Autor:
Katrina Hope, Ben Chant, Thomas Hinton, Adrian H. Kendrick, Angus K. Nightingale, Julian F. R. Paton, Emma C. Hart
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 13 (2023)
Background An elevated ventilatory efficiency slope during exercise (minute ventilation/volume of expired CO2; VE/VCO2 slope) is a strong prognostic indicator in heart failure. It is elevated in people with heart failure with preserved ejection, many
Externí odkaz:
https://doaj.org/article/085ed34a9b68452c889b245ba69f9dfb
Autor:
Iwan Harries, Giovanni Biglino, Kerrie Ford, Martin Nelson, Gui Rego, Prashant Srivastava, Matthew Williams, Bostjan Berlot, Estefania De Garate, Anna Baritussio, Kate Liang, Mai Baquedano, Nikesh Chavda, Christopher Lawton, Andrew Shearn, Sophie Otton, Lisa Lowry, Angus K. Nightingale, Juan Carlos Plana, David Marks, Costanza Emanueli, Chiara Bucciarelli-Ducci
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 43, Iss , Pp 101134- (2022)
Background: Anthracycline cardiotoxicity is a significant clinical challenge. Biomarkers to improve risk stratification and identify early cardiac injury are required. Objectives: The purpose of this pilot study was to prospectively characterize anth
Externí odkaz:
https://doaj.org/article/0d606e1165944fadb2c96627f33df38c
Autor:
Jonathan C. L. Rodrigues, Matthew F. R. Jaring, Melissa C. Werndle, Konstantina Mitrousi, Stephen M. Lyen, Angus K. Nightingale, Mark C. K. Hamilton, Stephanie L. Curtis, Nathan E. Manghat, Julian F. R. Paton, Emma C. Hart
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract Background It has been estimated that 20–30% of repaired aortic coarctation (CoA) patients develop hypertension, with significant cardiovascular morbidity and mortality. Vertebral artery hypoplasia (VAH) with an incomplete posterior circle
Externí odkaz:
https://doaj.org/article/80fa721602ce478386952b292c99e2c2
Autor:
Maria Pufulete, Rachel Maishman, Lucy Dabner, Julian P. T. Higgins, Chris A. Rogers, Mark Dayer, John MacLeod, Sarah Purdy, William Hollingworth, Morten Schou, Manuel Anguita-Sanchez, Patric Karlström, Michael Kleiner Shochat, Theresa McDonagh, Angus K. Nightingale, Barnaby C. Reeves
Publikováno v:
Systematic Reviews, Vol 7, Iss 1, Pp 1-21 (2018)
Abstract Background We estimated the effectiveness of serial B-type natriuretic peptide (BNP) blood testing to guide up-titration of medication compared with symptom-guided up-titration of medication in patients with heart failure (HF). Methods Syste
Externí odkaz:
https://doaj.org/article/ba845ddcaad84227a1963e8edab571a2
Autor:
Krzysztof Narkiewicz, MD, Laura E.K. Ratcliffe, BSc, MBBS, Emma C. Hart, PhD, Linford J.B. Briant, PhD, Marzena Chrostowska, PhD, Jacek Wolf, MD, Anna Szyndler, MD, Dagmara Hering, MD, Ana P. Abdala, PhD, Nathan Manghat, MD, Amy E. Burchell, MA, BMBCh, Claire Durant, PhD, Melvin D. Lobo, Paul A. Sobotka, MD, Nikunj K. Patel, MBBS, MD, James C. Leiter, MD, Zoar J. Engelman, PhD, Angus K. Nightingale, MB, BChir, MD, Julian F.R. Paton, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 5, Pp 313-324 (2016)
Animal and human data indicate pathological afferent signaling emanating from the carotid body that drives sympathetically mediated elevations in blood pressure in conditions of hypertension. This first-in-man, proof-of-principle study tested the saf
Externí odkaz:
https://doaj.org/article/090de4c0ffaa48999a72a1b604d2cccd
Autor:
Giovanni Biglino, Amy Burchell, Jonathan Rodrigues, Robert D.M. Gray, Emma C. Hart, Julian F.R. Paton, Nathan E. Manghat, Andreas Baumbach, Angus K. Nightingale
Publikováno v:
Artery Research, Vol 16 (2016)
Externí odkaz:
https://doaj.org/article/8c43c9243b1446d99674a3fd03f3995c
Autor:
Nathan E. Manghat, Elizabeth Robinson, Konstantina Mitrousi, Jonathan C.L. Rodrigues, Thomas Hinton, Julian F.R. Paton, Richard G. Wise, Angus K. Nightingale, Emma C. Hart
Publikováno v:
Manghat, N E, Robinson, E, Mitrousi, K, Rodrigues, J C L, Hinton, T C, Paton, J F R, Wise, R G, Nightingale, A K & Hart, E C J 2022, ' Cerebrovascular Variants and the Role of the Selfish Brain in Young-Onset Hypertension ', Hypertension, vol. 79, no. 6, pp. 1265-1274 . https://doi.org/10.1161/HYPERTENSIONAHA.121.18612
Background: Variants in the posterior anatomy of the cerebral circulation are associated with hypertension and lower cerebral blood flow in midlife (age ≈55 years); however, whether these variants are a result of aging or long-term exposure to high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50beded5f3d2bd1227eac98772b8ce7
https://research-information.bris.ac.uk/ws/files/329965019/HYPERTENSIONAHA.121.18612.pdf
https://research-information.bris.ac.uk/ws/files/329965019/HYPERTENSIONAHA.121.18612.pdf
Autor:
Vikas Kapil, Jane Lenart, Roger W. Brown, Angus K Nightingale, Thomas Hinton, Madhavan Menon, Paul Rylance, Una Martin, Francesco P. Cappuccio, Alexander Lawson, David J. Webb, Melvin D. Lobo, Stephen George, Mohammed Awais Hameed, Indranil Dasgupta
Publikováno v:
Lawson, A J, Hinton, T, Nightingale, A & al., E 2020, ' Non-adherence to antihypertensive medications is related to pill burden in apparent treatment resistant hypertensive individuals ', Journal of Hypertension . https://doi.org/10.1097/HJH.0000000000002398
Objective Nonadherence to medication is present in at least 50% of patients with apparent treatment-resistant hypertension. We examined the factors associated with nonadherence as detected by a liquid chromatography-tandem mass spectrometry (LC-MS/MS
Autor:
R.P. Baker, Julian F. R. Paton, Emma C. Hart, Angus K Nightingale, Katrina A. Hope, Thomas Hinton, Zoe H. Adams
Publikováno v:
Hinton, T C, Adams, Z H, Baker, R P, Hope, K, Paton, J F R, Hart, E C J & Nightingale, A K 2020, ' Investigation and treatment of high blood pressure in young people. Too much medicine or appropriate risk reduction ', Hypertension, vol. 75, no. 1, pp. 16–22 . https://doi.org/10.1161/HYPERTENSIONAHA.119.13820
Hypertension among young people is common, affecting 1 in 8 adults aged between 20 and 40 years. This number is likely to increase with lifestyle behaviors and lowering of hypertension diagnostic thresholds. Early-life factors influence blood pressur