Zobrazeno 1 - 10
of 3 431
pro vyhledávání: '"Angus C"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Application of stable isotopically labelled (SIL) molecules in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI) over a series of time points allows the temporal and spatial dynamics of biochemical reactions t
Externí odkaz:
https://doaj.org/article/e9e9b65dc3ac4818bd65e6284766b85a
Autor:
Syed A. Imam, Angus C. Hughes, Matt Carré, Heather Driscoll, Keith Winwood, Prabhuraj Venkatraman, Tom Allen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract A finite element model was developed for assessing the efficacy of rugby body padding in reducing the risk of sustaining cuts and abrasions. The model was developed to predict the onset of damage to a soft tissue simulant from concentrated i
Externí odkaz:
https://doaj.org/article/6a6842ebf6fe496fbdd1eae12d669212
Autor:
Simon J. Pelletier, Mickaël Leclercq, Florence Roux-Dalvai, Matthijs B. de Geus, Shannon Leslie, Weiwei Wang, TuKiet T. Lam, Angus C. Nairn, Steven E. Arnold, Becky C. Carlyle, Frédéric Precioso, Arnaud Droit
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Liquid Chromatography Mass Spectrometry (LC-MS) is a powerful method for profiling complex biological samples. However, batch effects typically arise from differences in sample processing protocols, experimental conditions, and data acquisit
Externí odkaz:
https://doaj.org/article/f411488984d94091a9e476c56116f06f
Publikováno v:
Frontiers in Ophthalmology, Vol 4 (2024)
UV light is known to cause damage to biomolecules in living tissue. Tissues of the eye that play highly specialised roles in forming our sense of sight are uniquely exposed to light of all wavelengths. While these tissues have evolved protective mech
Externí odkaz:
https://doaj.org/article/63c878b44c5c4acba52b4ae3d202f46a
Autor:
Jonathan S. Abebe, Yasmine Alwie, Erik Fuhrmann, Jonas Leins, Julia Mai, Ruth Verstraten, Sabrina Schreiner, Angus C. Wilson, Daniel P. Depledge
Publikováno v:
mSystems, Vol 9, Iss 7 (2024)
ABSTRACT Nanopore direct RNA sequencing (DRS) enables the capture and full-length sequencing of native RNAs, without recoding or amplification bias. Resulting data sets may be interrogated to define the identity and location of chemically modified ri
Externí odkaz:
https://doaj.org/article/6e0769599e5e491b9ab29a7c043b7473
Autor:
Matthijs B. de Geus, Shannon N. Leslie, TuKiet Lam, Weiwei Wang, Florence Roux-Dalvai, Arnaud Droit, Pia Kivisakk, Angus C. Nairn, Steven E. Arnold, Becky C. Carlyle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Alzheimer’s disease (AD) is a complex and heterogeneous neurodegenerative disorder with contributions from multiple pathophysiological pathways. One of the long-recognized and important features of AD is disrupted cerebral glucose metaboli
Externí odkaz:
https://doaj.org/article/3a59c8e75fa246d69d39653983e8997b
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-19 (2023)
Abstract Introduction Non-compliance is a common challenge for researchers and may reduce the power of an intention-to-treat analysis. Whilst a per protocol approach attempts to deal with this issue, it can result in biased estimates. Several methods
Externí odkaz:
https://doaj.org/article/8796d943ad1b4054a3918033f412e19a
Autor:
Valeria Lallai, TuKiet T. Lam, Rolando Garcia-Milian, Yen-Chu Chen, James P. Fowler, Letizia Manca, Daniele Piomelli, Kenneth Williams, Angus C. Nairn, Christie D. Fowler
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1143 (2024)
Given the increasing use of cannabis in the US, there is an urgent need to better understand the drug’s effects on central signaling mechanisms. Extracellular vesicles (EVs) have been identified as intercellular signaling mediators that contain a v
Externí odkaz:
https://doaj.org/article/8a5e8ff0fc664decb38c759a33e11e57
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9042 (2024)
Cataracts are the world’s leading cause of blindness, and diabetes is the second leading risk factor for cataracts after old age. Despite this, no preventative treatment exists for cataracts. The altered metabolism of excess glucose during hypergly
Externí odkaz:
https://doaj.org/article/003c4bcefb0144aa9aaeca5134f873a3
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-6 (2023)
Abstract Recent technological advances have opened the door to single-cell proteomics that can answer key biological questions regarding how protein expression, post-translational modifications, and protein interactions dictate cell state in health a
Externí odkaz:
https://doaj.org/article/7950f11c69a14e6ca417ecafbbc9e6b1