Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angqi Zhu"'
Autor:
Shuhao Zhang, Angqi Zhu, Fang Kong, Jianan Chen, Baoliang Lan, Guodong He, Kaixuan Gao, Lili Cheng, Xiaoou Sun, Chuangye Yan, Ligong Chen, Xiangyu Liu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The human organic cation transporter 1 (hOCT1), also known as SLC22A1, is integral to hepatic uptake of structurally diversified endogenous and exogenous organic cations, influencing both metabolism and drug pharmacokinetics. hOCT1 has been
Externí odkaz:
https://doaj.org/article/0ecd155174d94aee941dc2249d7ab9b6
Autor:
Yosuke Toyoda, Angqi Zhu, Fang Kong, Sisi Shan, Jiawei Zhao, Nan Wang, Xiaoou Sun, Linqi Zhang, Chuangye Yan, Brian K. Kobilka, Xiangyu Liu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The α1A-adrenergic receptor (α1AAR) belongs to the family of G protein-coupled receptors that respond to adrenaline and noradrenaline. α1AAR is involved in smooth muscle contraction and cognitive function. Here, we present three cryo-elec
Externí odkaz:
https://doaj.org/article/50bdf748659847fea35e92cceaacec7d
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Small solute carriers remain difficult to study by single particle cryo-EM. Here, the authors report the cryo-EM structure of human insulin-responsive glucose transporter GLUT4 (55 kDa) without rigid soluble domains or binders.
Externí odkaz:
https://doaj.org/article/c0376d2dbef2427aa2febc22b9ef7d4a
Autor:
Qian Wang, Bingting Ma, Qingtai Liang, Angqi Zhu, Hua Wang, Lili Fu, Xiaoxu Han, Xuanling Shi, Ye Xiang, Hong Shang, Linqi Zhang
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 775-786 (2020)
ABSTRACTOne of the major goals in HIV-1 vaccine development is to achieve properly folded and stabilized envelope glycoprotein (Env) trimers that mimic the native Env on the mature virion. Here, we design and characterize uncleaved prefusion-optimize
Externí odkaz:
https://doaj.org/article/c568ee4aef7e42aaac9957bb4e635227
Autor:
Xi Peng, Nan Wang, Angqi Zhu, Hanwen Xu, Jialu Li, Yanxia Zhou, Chen Wang, Qingjie Xiao, Li Guo, Fei Liu, Zhi-Jun Jia, Huaichuan Duan, Jianping Hu, Weidan Yuan, Jia Geng, Chuangye Yan, Xin Jiang, Dong Deng
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001386 (2021)
Plasmodium falciparum, the deadliest causal agent of malaria, caused more than half of the 229 million malaria cases worldwide in 2019. The emergence and spreading of frontline drug-resistant Plasmodium strains are challenging to overcome in the batt
Externí odkaz:
https://doaj.org/article/9f4f058d8df14e138116686afae63c4d
Autor:
Chuangye Yan, Xin Jiang, Jianping Hu, Xi Peng, Hanwen Xu, Chen Wang, Yanxia Zhou, Huaichuan Duan, Dong Deng, Zhi-jun Jia, Jialu Li, Jia Geng, Nan Wang, Fei Liu, Qingjie Xiao, Weidan Yuan, Li Guo, Angqi Zhu
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001386 (2021)
PLoS Biology
PLoS Biology
Plasmodium falciparum, the deadliest causal agent of malaria, caused more than half of the 229 million malaria cases worldwide in 2019. The emergence and spreading of frontline drug-resistant Plasmodium strains are challenging to overcome in the batt
Publikováno v:
Cell. 184(2)
Summary Proton-coupled monocarboxylate transporters MCT1-4 catalyze the transmembrane movement of metabolically essential monocarboxylates and have been targeted for cancer treatment because of their enhanced expression in various tumors. Here, we re
Autor:
Hua Wang, Lili Fu, Xuanling Shi, Angqi Zhu, Linqi Zhang, Hong Shang, Bingting Ma, Xiaoxu Han, Qian Wang, Qingtai Liang, Ye Xiang
Publikováno v:
Emerging Microbes & Infections
One of the major goals in HIV-1 vaccine development is to achieve properly folded and stabilized envelope glycoprotein (Env) trimers that mimic the native Env on the mature virion. Here, we design and characterize uncleaved prefusion-optimized (UFO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50de9fb6acac6b8139c2d0248220dea