Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Angiotensin II/pharmacology"'
Autor:
Armin Kurtz, Loïc Le Gal, Charlotte Wagner, Jacques-Antoine Haefliger, Maxime Pellegrin, Lucia Mazzolai, Paolo Meda, Tania Santoro
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association, vol. 8, no. 8, pp. e010823
Journal of the American Heart Association, vol. 8, no. 8, pp. e010823
Background Gap junction channels made of Connexin37 (Cx37) are expressed by aortic endothelial and smooth muscle cells of hypertensive mice, as well as by the renin‐secreting cells of kidneys. Methods and Results To decipher whether Cx37 has any ro
Autor:
Marco Eijken, Frank H. de Jong, Geert Kazemier, Richard A Feelders, Francien H van Nederveen, Johannes Hofland, Jacobie Steenbergen, Peter M. van Koetsveld, Wouter W. de Herder, Leo J. Hofland
Publikováno v:
Hofland, J, Steenbergen, J, Hofland, L J, van Koetsveld, P M, Eijken, M, van Nederveen, F H, Kazemier, G, de Herder, W W, Feelders, R A & de Jong, F H 2013, ' Protein kinase C-induced activin A switches adrenocortical steroidogenesis to aldosterone by suppressing CYP17A1 expression ', A J P: Endocrinology and Metabolism (Online), vol. 305, no. 6, pp. E736-44 . https://doi.org/10.1152/ajpendo.00034.2013
American Journal of Physiology, Endocrinology and Metabolism, 305(6), E736-E744. American Physiological Society
American Journal of Physiology, Endocrinology and Metabolism, 305(6), E736-E744. American Physiological Society
Functional zonation of the adrenal cortex is a consequence of the zone-specific expression of P450c17 ( CYP17A1) and its cofactors. Activin and inhibin peptides are differentially produced within the zones of the adrenal cortex and have been implicat
Autor:
Marc Maillard, Lucie Hofmann, Nicolas Glatz, Antoine G. Schneider, Bruno Vogt, Michel Burnier, Grégoire Wuerzner, Jean-Yves Meuwly, Philippe Eggimann
Publikováno v:
Nephrol Dial Transplant.
Nephrol Dial Transplant
Nephrology, Dialysis, Transplantation, vol. 27, no. 2, pp. 674-681
Nephrol Dial Transplant
Nephrology, Dialysis, Transplantation, vol. 27, no. 2, pp. 674-681
Background Acute kidney injury (AKI) is a common and important complication of critical illness associated with increased morbidity, mortality and costs. Alterations in renal perfusion are thought to play a central role in its pathogenesis. This caus
Autor:
Catherine M. Pastor
Publikováno v:
European Journal of Pharmacology, Vol. 494, No 2-3 (2004) pp. 191-7
The rat portal vein is a useful pharmacological model to study the contractions of smooth muscle cells through both receptor-dependent and receptor-independent mechanisms. We previously showed that sepsis decreases the spontaneous and agonist-induced
Autor:
Randall K. Packer, Shana Ageloff, Mark A. Knepper, Heddwen L. Brooks, S. Turban, Robert A. Fenton, Shyama Masilamani, Jakob Nielsen, Kathleen Beutler
Publikováno v:
Beutler, K T, Masilamani, S, Turban, S, Nielsen, J, Brooks, H L, Ageloff, S, Fenton, R A, Packer, R K & Knepper, M A 2003, ' Long-term regulation of ENaC expression in kidney by angiotensin II ', Hypertension, vol. 41, no. 5, pp. 1143-50 . https://doi.org/10.1161/01.HYP.0000066129.12106.E2
We carried out semiquantitative immunoblotting of kidney to identify apical sodium transporter proteins whose abundances are regulated by angiotensin II. In NaCl-restricted rats (0.5 mEq Na/200 g BW/d), the type 1 angiotensin II receptor (AT 1 recept
Publikováno v:
Endocrinology. 143:3096-3104
Seminiferous tubule contraction, an important step in the regulation of spermatogenesis and testicular sperm output, is regulated by several agonists. In the present paper, we investigated whether angiotensin II (Ang II) may have a place among them.
Publikováno v:
Journal of the American Society of Nephrology. 7(7):1015-1023
This study approaches the question of whether angiotensin II (AngII) and transforming growth factor beta (TGF-beta) are important mediators for mesangial heparan sulfate proteoglycan (HSPG) production. This might explain the beneficial effects of ang
Autor:
Chui-Wa Chow, Joseph Leung, Man-Fai Lam, Loretta Y.Y. Chan, Ai-Ing Lim, Kar-Neng Lai, Sydney C.W. Tang
Publikováno v:
Journal of Translational Medicine, Vol 9, Iss 1, p 169 (2011)
Journal of Translational Medicine
Journal of Translational Medicine
BACKGROUND: Inhibition of the renin-angiotensin-aldosterone system (RAAS) slows down the progression of chronic renal diseases (CKD) including IgA nephropathy (IgAN). Herein, we studied the pathogenetic roles of aldosterone (Aldo) in IgAN. METHODS: H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe56b1efdba2275e8a86e478074fdd3
http://hdl.handle.net/10722/163403
http://hdl.handle.net/10722/163403
Autor:
Laura E. Benjamin, Daniel Henrion, Carlos Labat, Aurelie Nguyen Dinh Cat, Frederic Jaisser, Laurent Loufrani, Patrick Lacolley, Violaine Griol-Charhbili, Nicolette Farman
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2010, 24 (7), pp.2454-2463. ⟨10.1096/fj.09-147926⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2010, 24 (7), pp.2454-63. ⟨10.1096/fj.09-147926⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2010, 24 (7), pp.2454-2463. ⟨10.1096/fj.09-147926⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2010, 24 (7), pp.2454-63. ⟨10.1096/fj.09-147926⟩
International audience; Pathophysiological aldosterone (aldo)/mineralocorticoid receptor (MR) signaling has significant effects on the cardiovascular system, resulting in hypertension and cardiovascular remodeling; however, the specific contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424e61bcbc282bc1923bf678d1d41552
https://hal.archives-ouvertes.fr/hal-02510516
https://hal.archives-ouvertes.fr/hal-02510516
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10070 (2010)
PLoS ONE
PloS one, 5 (4
PLoS ONE
PloS one, 5 (4
Angiotensin II (Ang II) plays a major role in the pathogenesis of insulin resistance and diabetes by inhibiting insulin's metabolic and potentiating its trophic effects. Whereas the precise mechanisms involved remain ill-defined, they appear to be as