Methionine tumor starvation by erythrocyte-encapsulated methionine gamma-lyase activity controlled with per os vitamin B6

Autor: Yann Godfrin, Vanessa Bourgeaux, Angie Tainturier, Delphine Maucort-Boulch, Françoise Horand, Karine Senechal, Karine Aguera, Jérôme Honnorat, Willy Berlier

Publikováno v: Cancer Medicine
Cancer Medicine, 2017, 6, pp.1437-1452. ⟨10.1002/cam4.1086⟩
Cancer Medicine, Wiley, 2017, 6, pp.1437-1452. ⟨10.1002/cam4.1086⟩

Erymet is a new therapy resulting from the encapsulation of a methionine gamma‐lyase (MGL; EC number 4.4.1.11) in red blood cells (RBC). The aim of this study was to evaluate erymet potential efficacy in methionine (Met)‐dependent cancers. We pro

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https://hal.science/hal-02049678