Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Angharad G Davis"'
Autor:
Angharad G Davis, Robert J Wilkinson
Publikováno v:
EClinicalMedicine, Vol 35, Iss , Pp 100871- (2021)
Externí odkaz:
https://doaj.org/article/c9638a14ee4f4f1299d67604c2374a1f
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Tuberculous meningitis (TBM), the most severe form of tuberculosis, causes death in approximately 25% cases despite antibiotic therapy, and half of survivors are left with neurological disability. Mortality and morbidity are contributed to by a dysre
Externí odkaz:
https://doaj.org/article/dfa5c04e53fc4d41b642d444bfe22383
Autor:
Nathan C Bahr, Fiona V Cresswell, Nguyen Thuy Thuong Thuong, Rachel P.J. Lai, Angharad G. Davis, David R Boulware, Robert J Wilkinson, Johan Schoeman, Marise Bremer, Joseph Donovan, Ronald Van Toorn, Guy E Thwaites, Ariba Dadabhoy
Publikováno v:
Wellcome Open Research, Vol 5 (2021)
A dysregulated host immune response significantly contributes to morbidity and mortality in tuberculous meningitis (TBM). Effective host directed therapies (HDTs) are critical to improve survival and clinical outcomes. Currently only one HDT, dexamet
Externí odkaz:
https://doaj.org/article/1082f9028b78463baff862754b13c9a1
Autor:
Angharad G. Davis, Sam Nightingale, Priscilla E. Springer, Regan Solomons, Ana Arenivas, Robert J. Wilkinson, Suzanne T. Anderson, Felicia C. Chow, Tuberculous Meningitis International Research Consortium
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
In those who survive tuberculous meningitis (TBM), the long-term outcome is uncertain; individuals may suffer neurocognitive, functional and psychiatric impairment, which may significantly affect their ability to lead their lives as they did prior to
Externí odkaz:
https://doaj.org/article/fe510c7842cf4fc48788fca64ab29c9c
Autor:
Angharad G Davis, Anna J Dreyer, Christine Albertyn, Mpumi Maxebengula, Cari Stek, Sean Wasserman, Suzaan Marais, Kathleen Bateman, Mark Solms, John Joska, Robert J Wilkinson, Sam Nightingale
BackgroundCognitive impairment is reported as a common complication in adult tuberculous meningitis (TBM), yet few studies have systematically assessed the frequency and nature of impairment. Moreover, the impact of impairment on functioning and medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27c46aa44137f4edf59964552f38f7a
Autor:
Angharad G Davis, Sean Wasserman, Cari Stek, Mpumi Maxebengula, C Jason Liang, Stephani Stegmann, Sonya Koekemoer, Amanda Jackson, Yakub Kadernani, Marise Bremer, Remy Daroowala, Saalikha Aziz, Rene Goliath, Louise Lai Sai, Thandi Sihoyiya, Paolo Denti, Rachel P J Lai, Thomas Crede, Jonathan Naude, Patryk Szymanski, Yakoob Vallie, Ismail Abbas Banderker, Muhammed S Moosa, Peter Raubenheimer, Sally Candy, Curtis Offiah, Gerda Wahl, Isak Vorster, Gary Maartens, John Black, Graeme Meintjes, Robert J Wilkinson
Background Drug regimens that include intensified antibiotics alongside effective anti-inflammatory therapies may improve outcomes in tuberculous meningitis (TBM). Safety data on their use in combination and in the context of human immunodeficiency v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42911404e9e173481f72774be3e0f3f
Autor:
Angharad G Davis, Sean Wasserman, Cari Stek, Mpumi Maxebengula, C. Jason Liang, Stephani Stegmann, Sonya Koekemoer, Amanda Jackson, Yakub Kadernani, Marise Bremer, Remy Daroowala, Saalikha Aziz, Rene Goliath, Louise Lai Sai, Thandi Sihoyiya, Paolo Denti, Rachel PJ Lai, Thomas Crede, Jonathan Naude, Patryk Szymanski, Yakoob Vallie, Ismail Abbas Banderker, Muhammed S Moosa, Peter Raubenheimer, Sally Candy, Curtis Offiah, Gerda Wahl, Isak Vorster, Gary Maartens, John Black, Graeme Meintjes, Robert J Wilkinson
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
BackgroundDrug regimens which include intensified antibiotics alongside effective anti-inflammatory therapies may improve outcomes in Tuberculous Meningitis (TBM). Safety data on their use in combination and in the context of HIV is needed to inform
Publikováno v:
Expert opinion on pharmacotherapy. 22(15)
Introduction: The incidence of human immunodeficiency virus-1 (HIV-1) associated meningitis has been declining in the post-combination antiretroviral treatment (ART) era, although survival rates remain low for the common causes like tuberculosis and
Autor:
Angharad G. Davis, Sean Wasserman, Mpumi Maxebengula, Cari Stek, Marise Bremer, Remy Daroowala, Saalikha Aziz, Rene Goliath, Stephani Stegmann, Sonya Koekemoer, Amanda Jackson, Louise Lai Sai, Yakub Kadernani, Thandi Sihoyiya, C.Jason Liang, Lori Dodd, Paolo Denti, Thomas Crede, Jonathan Naude, Patryk Szymanski, Yakoob Vallie, Ismail Banderker, Shiraz Moosa, Peter Raubenheimer, Rachel P.J. Lai, John Joska, Sam Nightingale, Anna Dreyer, Gerda Wahl, Curtis Offiah, Isak Vorster, Sally Candy, Frances Robertson, Ernesta Meintjes, Gary Maartens, John Black, Graeme Meintjes, Robert J. Wilkinson
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: Tuberculous meningitis (TBM) is the most lethal form of tuberculosis with a mortality of ~50% in those co-infected with HIV-1. Current antibiotic regimens are based on those known to be effective in pulmonary TB and do not account for the
Autor:
Paolo Denti, John A. Joska, Gerda Wahl, Shiraz Moosa, John H. Black, Robert J. Wilkinson, Louise Lai Sai, Marise Bremer, Ernesta M. Meintjes, Graeme Meintjes, Sally Candy, Patryk Szymanski, Saalikha Aziz, Lori E. Dodd, Rene Goliath, Frances Robertson, Cari Stek, Ismail Banderker, Anna J. Dreyer, Sean Wasserman, Isak D Vorster, Amanda Jackson, Yakub E Kadernani, Sam Nightingale, Jonathan Naude, Angharad G Davis, Gary Maartens, Thomas Crede, C.Jason Liang, Peter J Raubenheimer, Remy Daroowala, Yakoob Vallie, Mpumi Maxebengula, Rachel P. J. Lai, Stephani Stegmann, Sonya Koekemoer, Thandi Sihoyiya, Curtis Offiah
Publikováno v:
Wellcome Open Research
Background: Tuberculous meningitis (TBM) is the most lethal form of tuberculosis with a mortality of ~50% in those co-infected with HIV-1. Current antibiotic regimens are based on those known to be effective in pulmonary TB and do not account for the