Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Angelyn C. C. Hor"'
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98945 (2014)
Twist1 encodes a transcription factor that plays a vital role in limb development. We have used a tamoxifen-inducible Cre transgene, Ubc-CreERT2, to generate time-specific deletions of Twist1 by inducing Cre activity in mouse embryos at different age
Externí odkaz:
https://doaj.org/article/b28aa4198f36498da00ccf0620c7d314
Autor:
David A.F. Loebel, Patrick P.L. Tam, You-Tzung Chen, Heidi Bildsoe, Vanessa Jones, Antony W. Braithwaite, Angelyn C. C. Hor, Richard R. Behringer
Publikováno v:
Developmental Biology. 374(2):295-307
The basic helix–loop–helix transcription factor Twist1 is a key regulator of craniofacial development. Twist1-null mouse embryos exhibit failure of cephalic neural tube closure and abnormal head development and die at E11.0. To dissect the functi
Autor:
Angelyn C. C. Hor, Vanessa Jones, David A.F. Loebel, Patrick P.L. Tam, Richard R. Behringer, You-Tzung Chen, Heidi Bildsoe
Publikováno v:
Developmental Biology. 362:132-140
Development of the mouse forelimb bud depends on normal Twist1 activity. Global loss of Twist1 function before limb bud formation stops limb development and loss of Twist1 throughout the mesenchyme after limb bud initiation leads to polydactyly, the
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98945 (2014)
PLoS ONE
PLoS ONE
Twist1 encodes a transcription factor that plays a vital role in limb development. We have used a tamoxifen-inducible Cre transgene, Ubc-CreERT2, to generate time-specific deletions of Twist1 by inducing Cre activity in mouse embryos at different age
Autor:
Loebel, David A. F.1,2 dloebel@cmri.org.au, Hor, Angelyn C. C.1, Bildsoe, Heidi K.1,2, Tam, Patrick P. L.1,2
Publikováno v:
PLoS ONE. Jun2014, Vol. 9 Issue 6, p1-9. 9p.