Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Angelos Papatheodorou"'
Autor:
Esther Latres, Jason Mastaitis, Wen Fury, Lawrence Miloscio, Jesus Trejos, Jeffrey Pangilinan, Haruka Okamoto, Katie Cavino, Erqian Na, Angelos Papatheodorou, Tobias Willer, Yu Bai, Jee Hae Kim, Ashique Rafique, Stephen Jaspers, Trevor Stitt, Andrew J. Murphy, George D. Yancopoulos, Jesper Gromada
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Inhibition of GDF8 increases muscle mass in mice, but is less effective in monkeys and humans. Here the authors show that activin A also inhibits muscle hypertrophy and that concomitant inhibition of activin A and GDF8 synergistically increases muscl
Externí odkaz:
https://doaj.org/article/27340da65b5f447ab24e6f3d810b70d9
Autor:
Matthew Bank MD, Katie Gibbs DO, Cristina Sison PhD, Nawshin Kutub PhD, Angelos Papatheodorou, Samuel Lee, Adam Stein MD, Ona Bloom PhD
Publikováno v:
Geriatric Orthopaedic Surgery & Rehabilitation, Vol 9 (2018)
Objective: To identify clinical or demographic variables that influence long-term mortality, as well as in-hospital mortality, with a particular focus on the effects of age. Summary and Background Data: Cervical spine fractures with or without spinal
Externí odkaz:
https://doaj.org/article/25f8c5eed15744f79d07ed17a7c8cba6
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99621 (2014)
Intervertebral disc degeneration is accompanied by elevated levels of inflammatory cytokines that have been implicated in disease etiology and matrix degradation. While the effects of inflammatory stimulation on disc cell metabolism have been well-st
Externí odkaz:
https://doaj.org/article/dd04d5ef23c04f3f8f03ffbb4d557ff5
Autor:
Ona Bloom, Angelos Papatheodorou, Debra J. Morrison, Samuel Lee, Adam Stein, Aya Shnawa, Katie Gibbs
Publikováno v:
The Journal of Spinal Cord Medicine
To determine circulating levels of antibodies (IgA, IgM, IgG1-4) in individuals with SCI as compared to uninjured individuals.Prospective, observational study.Outpatient clinic of a Department of Physical Medicine and Rehabilitation and research inst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28aed38ccea0d78bb4833bfdc34540a
https://pubmed.ncbi.nlm.nih.gov/33443466
https://pubmed.ncbi.nlm.nih.gov/33443466
Autor:
Ona Bloom, Jennifer R. Morgan, Courtney K. M. Waterbury, Angelos Papatheodorou, Joseph D. Buxbaum, Stephanie A. Bryant, Paige E. Herman, J. Joshua Smith, Anthony A. Arcese, Joseph R. Herdy
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
In mammals, spinal cord injury (SCI) leads to dramatic losses in neurons and synaptic connections, and consequently function. Unlike mammals, lampreys are vertebrates that undergo spontaneous regeneration and achieve functional recovery after SCI. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67cf42773b9f1b495c66848cf89400e
http://link.springer.com/article/10.1038/s41598-017-18757-1
http://link.springer.com/article/10.1038/s41598-017-18757-1
Autor:
Christian Grant, Thomas Coleman, Czeslawa Kowal, Venkatesh Jeganathan, Kai Fan Cheng, Angelos Papatheodorou, James M. Crawford, Ona Bloom, Sonya VanPatten, Mingzhu He, Bruce T. Volpe, Yousef Al-Abed, Nathalie Meurice, Ahmad Altiti, Betty Diamond, Shan Sun
Publikováno v:
Journal of Medicinal Chemistry. 59:8859-8867
Systemic lupus erythematosus is an autoimmune disease that can affect numerous tissues and is characterized by the production of nuclear antigen-directed autoantibodies (e.g., anti-dsDNA). Using a combination of virtual and ELISA-based screens, we ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e373c53a049e401bed6bf864d28cbbd
https://doi.org/10.1021/acs.jmedchem.6b00694
https://doi.org/10.1021/acs.jmedchem.6b00694
Autor:
Jason Mastaitis, Andrew J. Murphy, Jesus A. Trejos, Stephen Jaspers, Jeffrey Pangilinan, Trevor Stitt, Erqian Na, Esther Latres, Yu Bai, George D. Yancopoulos, Lawrence Miloscio, Jesper Gromada, Ashique Rafique, Wen Fury, Jee Hae Kim, Tobias Willer, Katie Cavino, Haruka Okamoto, Angelos Papatheodorou
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Growth and differentiation factor 8 (GDF8) is a TGF-β superfamily member, and negative regulator of skeletal muscle mass. GDF8 inhibition results in prominent muscle growth in mice, but less impressive hypertrophy in primates, including man. Broad T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87739244226941d93603a7a609426820
https://doi.org/10.1038/ncomms15153
https://doi.org/10.1038/ncomms15153
Autor:
Cristina Sison, Ona Bloom, Angelos Papatheodorou, Katie Gibbs, Adam Stein, Peter Davies, Matthew Bank
Inflammation in traumatic spinal cord injury (SCI) has been proposed to promote damage acutely and oppose functional recovery chronically. However, we do not yet understand the signals that initiate or prolong inflammation in persons with SCI. High-M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62acfb276abb95afb898ae9c0a65b805
https://europepmc.org/articles/PMC6436020/
https://europepmc.org/articles/PMC6436020/
Autor:
Ona, Bloom, Kai Fan, Cheng, Kai Fen, Cheng, Mingzhu, He, Angelos, Papatheodorou, Bruce T, Volpe, Betty, Diamond, Yousef, Al-Abed
Publikováno v:
Proceedings of the National Academy of Sciences. 108:10255-10259
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of pathogenic autoantibodies, many of which are directed against nuclear antigens, in particular double-stranded (ds) DNA. Both clinical studies and anim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56383b9fb16532114d8a9e9485f3f1b
https://doi.org/10.1073/pnas.1103555108
https://doi.org/10.1073/pnas.1103555108
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e99621 (2014)
PLoS ONE, Vol 9, Iss 6, p e99621 (2014)
Intervertebral disc degeneration is accompanied by elevated levels of inflammatory cytokines that have been implicated in disease etiology and matrix degradation. While the effects of inflammatory stimulation on disc cell metabolism have been well-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b241d056f38096d3eeee8841c6adccc9
http://europepmc.org/articles/PMC4061011
http://europepmc.org/articles/PMC4061011