Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Angelo Scatturin"'
Autor:
Angelo Scatturin, Vertuani Gianni, Rita Pecoraro, Alessandro Dalpiaz, Marisa Boggian, Maria Ferretti, Susanna Spisani
Publikováno v:
Arzneimittelforschung. 49:873-877
The conformation of several Phe-D-Leu-Phe-D-Leu-Phe analogues was analyzed using infrared absorption and circular dichroism. Their effect on human neutrophils was verified by receptor binding and chemotaxis assays. The results demonstrate that the co
Autor:
C. Falcomer, G. Pochetti, Vertuani G, Maurizio Ricci, M. Boggian, C. Ross, Angelo Scatturin, S. Cerrini
Publikováno v:
Scopus-Elsevier
The conformational behaviour of the peptide antibiotic leucinostatin A has been studied in solvents of different polarity using circular dichroism (CD) and infrared (i.r.) absorption. I.r. studies provided evidence of an intramolecularly hydrogen-bon
Publikováno v:
International Journal of Peptide and Protein Research. 34:409-415
The tripeptide N-formyl-L-Met-L-Leu-L-Phe-OMe (FMLP-OMe) crystallizes in the orthorhombic system, space group P 2(1)2(1)2(1), with the following unit-cell parameters: a = 21.727, b = 21.836, c = 5.133 A, Z = 4. The structure has been solved and refin
Autor:
Gaia Colombo, Fabrizio Bortolotti, Sergio Tanganelli, Luca Ferraro, Paolo Giunchedi, Angelo Scatturin, Alessandro Dalpiaz, Paola Russo, Enea Menegatti, Elisabetta Gavini
Publikováno v:
Journal of Pharmaceutical Sciences. 97:4889-4903
N(6)-cyclopentyladenosine (CPA) has neuronal anti-ischemic properties, but it is not absorbed into the brain from the bloodstream, where it shows poor stability and induces side effects. Microparticulate drug delivery systems designed for CPA nasal a
Autor:
F. Vitali, Martina Scaglianti, Fabrizio Bortolotti, Alessandro Dalpiaz, Barbara Pavan, Stefano Manfredini, Angelo Scatturin, Carla Biondi
Publikováno v:
International Journal of Pharmaceutics. 291:171-181
Diclofenac (Diclo), its ascorbic acid (AA) or 6-amino-AA (AA-NH2) pro-drugs (AA-Diclo or AA-NH-Diclo) were prepared and evaluated on human retinal pigment epithelium (HRPE) cells to investigate their ability to interact with the vitamin C transporter
Autor:
Silvia Vertuani, Stefano Manfredini, Martina Scaglianti, Giuliano Marzola, Angelo Scatturin, Federica Vitali, Luca Ferraro, Carla Biondi, Barbara Pavan, Alessandro Dalpiaz, Puttur D. Prasad, Fabrizio Bortolotti, Sergio Tanganelli
Publikováno v:
European Journal of Pharmaceutical Sciences. 24:259-269
Ascorbic acid (AA) or 6-Br-ascorbate (BrAA) conjugation has been investigated as a tool to improve brain drug delivery by the Vitamin C transporter SVCT2. To this aim, the effects of AA- or BrAA-conjugation on drug affinity and uptake have been asses
Autor:
Federica Vitali, Martina Scaglianti, Puttur D. Prasad, Sergio Tanganelli, Carla Biondi, Luca Ferraro, Fabrizio Bortolotti, Stefano Manfredini, Angelo Scatturin, Barbara Pavan, Alessandro Dalpiaz
Publikováno v:
Journal of Pharmaceutical Sciences. 93:78-85
Continuing our studies on SVCT2 ascorbic acid (AA) transporter-mediated drug delivery of neurotropic agents, we have now investigated the in vitro intracellular uptake of Diclofenac (Diclo) and its conjugate (AA-Diclo), both characterized by high aff
Autor:
Barbara Malawska, Angelo Scatturin
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 3:341-348
The chemical diversity and various mechanisms of action of anticonvulsants make it difficult to identify a common pharmacophore. The present review outlines different pharmacophore models for anticonvulsant activity with emphasis on the development o
Autor:
A. Dalpiaz, Maria Angela Vandelli, Angelo Scatturin, Carla Biondi, Barbara Pavan, Flavio Forni
Publikováno v:
International Journal of Pharmaceutics. 242:115-120
We report a preliminary study evaluating the encapsulation modalities in microparticles of the antiischemic drug N(6)-cyclopentyladenosine (CPA). The effects of release systems have been evaluated on the stability in human whole blood of CPA and its
Autor:
Maria Angela Vandelli, Angelo Scatturin, Carla Biondi, Flavio Forni, Alessandro Dalpiaz, Barbara Pavan
Publikováno v:
Journal of Controlled Release. 73:303-313
A study concerning the feasibility of microsphere use as sustained delivery systems for N 6 -cyclopentyladenosine (CPA) administration has been performed. The release of this drug and the related stability effects in human whole blood have been teste