Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Angelo Palmese"'
Autor:
Laura Riccetti, Samantha Sperduti, Clara Lazzaretti, Danièle Klett, Francesco De Pascali, Elia Paradiso, Silvia Limoncella, Francesco Potì, Simonetta Tagliavini, Tommaso Trenti, Eugenio Galano, Angelo Palmese, Abhijeet Satwekar, Jessica Daolio, Alessia Nicoli, Maria Teresa Villani, Lorenzo Aguzzoli, Eric Reiter, Manuela Simoni, Livio Casarini
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Recombinant follicle-stimulating hormone (FSH) (follitropin alfa) and biosimilar preparations are available for clinical use. They have specific FSH activity and a unique glycosylation profile dependent on source cells. The aim of the study is to com
Externí odkaz:
https://doaj.org/article/d4b1c3b28da940e486f506297958f941
Autor:
Antonio Datola, Abhijeet Satwekar, Nadine Barron, Sawako DeRosa, Brittany Tomascak, Jessica Dawson, Angelo Palmese, Mara Rossi
Publikováno v:
Biotechnology and Bioengineering. 120:465-481
There is an increasing interest in the generation of Fc-fusion molecules to exploit the effector functions of Fc and the fusion partner, towards improving the therapeutic potential. The Fc-fusion molecules have unique structural and functional attrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fd295c16fe3790e521a5aa17150cfb
https://doi.org/10.1002/bit.28281
https://doi.org/10.1002/bit.28281
Autor:
Francesco Nevelli, Angelo Palmese, Ralf Gleixner, Flavio Peroglio, Cosimo-Walter D’Acunto, Aurora Dadone, Thomas D’Hooghe, Monica Lispi
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8040
Various preparations of follicle-stimulating hormone (FSH) are commercially available; however, they differ in glycoforms composition and purity owing to their respective sources. Additional chemical/physical changes can also be introduced during man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb456b35c29dead8fa12a957d2f05a8
Autor:
Domenico Rizzo, Linda Cerofolini, Stefano Giuntini, Luisa Iozzino, Carlo Pergola, Francesca Sacco, Angelo Palmese, Enrico Ravera, Claudio Luchinat, Fabio Baroni, Marco Fragai
Publikováno v:
Journal of the American Chemical Society
Multispecific biologics are an emerging class of drugs, in which antibodies and/or proteins designed to bind pharmacological targets are covalently linked or expressed as fusion proteins to increase both therapeutic efficacy and safety. Epitope mappi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b24109ed6388f9fe18820c8f85cca229
https://doi.org/10.1021/jacs.2c03232
https://doi.org/10.1021/jacs.2c03232
Autor:
Lucio Manzi, Nunzio Sepe, Walter Migliaccio, Ludovica Lanzoni, Luisa Iozzino, Fabrizia D’Angelo, Lucia Colarusso, Susana Montenegro, Angelo Palmese, Thomas D’Hooghe, Alfredo Ulloa-Aguirre, Yulia Koloda, Monica Lispi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6762
Although the full primary structures of the alfa and beta subunits of reference r-hFSH-alfa and its biosimilars are identical, cell context-dependent differences in the expressing cell lines and manufacturing process can lead to variations in glycosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266008041c927d7629af795674928ca5
https://lirias.kuleuven.be/handle/20.500.12942/713214
https://lirias.kuleuven.be/handle/20.500.12942/713214
Publikováno v:
Rapid Communications in Mass Spectrometry. 36
We show evidence of cysteinylation on Cys252 of recombinant human p40 subunit of interleukin 12 (IL-12). This was reported in 1996. However, no paper detailing this concept has been published yet. Our paper reports the quantification of Cys252 cystei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047b32abfd346e14021a5903fc89092b
https://doi.org/10.1002/rcm.9313
https://doi.org/10.1002/rcm.9313
Autor:
Anna Illiano, Gabriella Pinto, Maria Antonietta Carrera, Angelo Palmese, Riccardo Di Novella, Paolo Casoria, Angela Amoresano
Safeguarding the biodiversity of plant species is of fundamental importance for their defense against pests and diseases even through the maintenance and dissemination of ancient agricultural traditions rooted within the small rural environments. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741f42dc81d59649e0977dd3286ff1e2
http://hdl.handle.net/11367/104433
http://hdl.handle.net/11367/104433
Publikováno v:
Fertility and Sterility. 118:e283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab594f381e51e755ddcc587a5680c9b4
https://doi.org/10.1016/j.fertnstert.2022.08.788
https://doi.org/10.1016/j.fertnstert.2022.08.788
Autor:
David Brühlmann, Jürgen Hemberger, Zeynep Manco, Alessandra D'Angelo, Eugenio Galano, Jonathan Souquet, Thomas Vuillemin, Abhijeet Satwekar, Markus Sauer, Angelo Palmese, Martin Jordan, Hervé Broly
Publikováno v:
Biotechnology and Bioengineering. 116:1017-1028
Glycosylation, a critical product quality attribute, may affect the efficacy and safety of therapeutic proteins in vivo. Chinese hamster ovary fed-batch cell culture batches yielded consistent glycoprofiles of a Fc-fusion antibody comprizing three di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acce949db3e51d8af6de126a0d3e8e20
https://doi.org/10.1002/bit.26930
https://doi.org/10.1002/bit.26930
Autor:
Alessandra Pistacchio, Fabio Baroni, Irene Cecchini, Roberta Verani, Mariano Stornaiuolo, Angelo Palmese, Carlo Pergola
Publikováno v:
European Journal of Pharmaceutical Sciences. 172:106139
A key aspect that must be supervised during the development of a biotherapeutic is the presence of elemental impurities in the final drug product: they must be quantified as to ensure that their concentrations does not affect patients’ safety. Regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4d8631c0bcc92f2eed4592fd601e14
https://doi.org/10.1016/j.ejps.2022.106139
https://doi.org/10.1016/j.ejps.2022.106139