Evidence for Differential Effects of Selective Somatostatin Receptor Subtype Agonists on α-Subunit and Chromogranin A Secretion and on Cell Viability in Human Nonfunctioning Pituitary Adenomas in Vitro

Autor: Angelo Margutti, Michael D. Culler, Roberto Padovani, Daniela Piccin, Maria Chiara Zatelli, John E. Taylor, Ettore C. degli Uberti, Luigi Cavazzini, Arianna Bottoni, Massimo Scanarini, Maria Rosaria Ambrosio

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 89:5181-5188

Somatostatin (SRIF) analogs interacting with SRIF receptor (SSTR) subtypes SSTR2 and SSTR5 reduce hormone secretion of pituitary adenomas, but their antiproliferative effects are still controversial. We investigated the in vitro effects of SRIF and S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfb1f4d5c3ad7143541d194b9d150cd
https://doi.org/10.1210/jc.2003-031954

Defective Hypothalamic Growth Hormone (GH)-Releasing Hormone Activity May Contribute to Declining GH Secretion with Age in Man1

Autor: Maria Rosaria Ambrosio, Angelo Margutti, E. C. Degli Uberti, Antonello E. Rigamonti, Giorgio Trasforini, E. Petrone, Silvano G. Cella, E. E. Müller

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 82:2885-2888

There is evidence that withdrawal of SRIH infusion in man promotes a rebound GH response that allegedly has been proposed to be related to the function of GHRH-producing neurons. In the present study we have evaluated whether a reduction in endogenou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::036cf732360eb9e379c6b3e841a0de09
https://doi.org/10.1210/jcem.82.9.4216

Contents, Vol. 63, 1996

Autor: Lorena Cattaneo, Silvano G. Cella, Margaret G. Eason, Takahiko Fujikawa, Stella Campo, Eugenio E. Müller, Peter J. Sharp, Ian C. Dunn, R. Pansini, Monica G. Ferrini, Silvina Creus, Cynthia L. Bethea, Karen S.L Lam, Man Fong Lee, Donna L. Maney, Ricardo S. Calandra, Sau Ping Tam, Mariolina Luceri, Florence Demay, Andreas Kjaer, Karen K. Beattie, Eliana Herminia Pellizzari, Angelo Margutti, Cynthia M. Kuhn, Alberto Valentini, Jørgen Warberg, Susana B. Rulli, Alejandro F. De Nicola, Kesami Sakaguchi, Andrea A. Widmann, Franco Minuto, Claudia A. Grillo, Kunio Nakashima, Gopesh Srivastava, Antonio Torsello, Gerardo G. Piroli, Frederik H.E. Schagen, Ulrich Knigge, Selva B. Cigorraga, Maria Rosaria Ambrosio, Melanie Pecins-Thompson, Gérard Tramu, Jean-Rémi Pape, Marie-Lise Thieulant, Shu Sudo, Ezio Ghigo, Reynold Francis, Victoria Lux-Lantos, Philip J. Larsen, Peter W.F. Wilson, Ettore C. degli Uberti, Richard Talbot, Christophe Tiffoche, Helen Sang, Silvano Cella, Katsumi Doh-ura, Takeshi Ohkubo, Giorgio Trasforini, Minoru Tanaka

Publikováno v: Neuroendocrinology. 63:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20f0f710d5884cb2c8083597bef0c48c
https://doi.org/10.1159/000127074

Contents, Vol. 56, 1992

Autor: Karen Curto, Garbiñe Aréchaga, Begoña Sánchez, Maria Inés Rodríguez Vida, Harold Kotzmann, Luis M. Garcia-Segura, Roberta Elisa Rossi, Douglas L. Foster, Ameae M. Walker, Ignacio Torres-Aleman, Francis J. P. Ebling, Jeffrey N. Wiemann, Lucinda Cacicedo, Matti Bergendahl, Carol Rutherford, Tetsu Yano, Andreas Kjaer, Paul E. Gottschall, Jarmo T. Laitinen, Junko Kadowaki, David Venzon, Samuel M. McCann, Victor E. Nahmod, Angelo Margutti, Marceline M. Brown, François Gilbert, María Claudia Kleid, Samuel Finkielman, Dennis W. Matt, Francesco Portaluppi, Gloria E. Hoffman, Maria L. Tedeschi, Harold E. Carlson, Michelle C. Ultmann, Jørgen Warberg, Raffaele Pansini, Elizabeth Spatola, Manuel Ramírez, Paul M. Plotsky, Carol Langford, Ettore C. degli Uberti, Lynn Fabre, S. Salvadori, Franco Sánchez-Franco, Flemming W. Bach, Robert A. Steiner, Raquel Aloyz, Umeko Marubayashi, Sonia García, Abba J. Kastin, Michael J. Woller, Roman Deyssig, Ruth I. Wood, Ricardo Martínez-Murillo, Mohan Viswanathan, Donald K. Clifton, Shim Minami, Juan M. Saavedra, Paul B. Nelson, Andrés Ozaita, Christoph Carl Zielinski, Julie A. Chowen, Fernando Aguado, Ilpo Huhtaniemi, Robert L. Goodman, Thomas Svoboda, Juan Manuel de Gandarias, Ei Terasawa, Giorgio Trasforini, Richard D. Olson, Dipak K. Sarkar, Bruce S. McEwen, Jacek Pinski, Gen Komaki, Osvaldo Vindrola, Ulrich Knigge, Maria Rosaria Ambrosio, Joseph Vassalotti, Scott D. Mendelson, Cecilia Aguila, L Vergnani, Sharada Karanth, Akira Arimura, Pilar Lardelli, C. Scott Whisnant, Helen I’Anson, Rexford S. Ahima, Alan G. Robinson, Martin Clodi, Marie C. Gelato, Kenneth Marsh, Linghe Pan, José Rodrigo, Wolfgang Woloszczuk, Richard E. Harlan, Anton Luger, Teresa Fernández, Timothy E. Sayles, Andrew V. Schally

Publikováno v: Neuroendocrinology. 56:I-VIII

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2545b2794ef0e6716caf5a1c8b4c5e5d
https://doi.org/10.1159/000126305

Selective activation of somatostatin receptor subtypes differentially modulates secretion and viability in human medullary thyroid carcinoma primary cultures: potential clinical perspectives

Autor: Arianna Bottoni, Maria Chiara Zatelli, Maria Rosa Pelizzo, Ettore C. degli Uberti, Gian Carlo Pansini, Daniela Piccin, Angelo Margutti, Andrea Luchin, Federico Tagliati, Marta Bondanelli, Cristina Vignali, Michael D. Culler

Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. We previously demonstrated that somatostatin (SRIH) reduces cell growth in the human MTC cell line, TT, which expresses all SRIH receptor (SSTR) subtyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fac5e5c2616e3bc709ff78aadffc2ec
http://hdl.handle.net/11392/1211320