Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Angelo Mandarino"'
Autor:
Angelo Mandarino, Swetha Thiyagarajan, Allana C. F. Martins, Roberto da Silva Gomes, Stefan W. Vetter, Estelle Leclerc
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1175 (2023)
Pancreatic cancer remains a disease that is very difficult to treat. S100 proteins are small calcium binding proteins with diverse intra- and extracellular functions that modulate different aspects of tumorigenesis, including tumor growth and metasta
Externí odkaz:
https://doaj.org/article/fe9d0106b9c546a6b221269547691144
Autor:
Angelo Mandarino
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-2 (2022)
Anti-retroviral therapy with drugs like dolutegravir is a powerful tool in both the treatment and prevention of HIV, but is limited by strict adherence to a daily therapeutic regimen. In a recent study, Deodhar, Sillman, and colleagues developed a do
Externí odkaz:
https://doaj.org/article/b186322164a34dd989a504b727eac768
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002540 (2012)
Herpes simplex virus type-1 (HSV-1) establishes latency in peripheral neurons, creating a permanent source of recurrent infections. The latent genome is assembled into chromatin and lytic cycle genes are silenced. Processes that orchestrate reentry i
Externí odkaz:
https://doaj.org/article/a581ea214a5f49e8888b2120c9947265
Autor:
Rafael G. Mendes, Zhongfan Liu, Alicja Bachmatiuk, Mark H. Rümmeli, Thomas Gemming, Anne K. Meyer, Britta Koch, Oliver G. Schmidt, Angelo Mandarino, Cordula Hirsch
Publikováno v:
Nano Research. 10:1980-1995
Graphene oxide shows great promise as a material for biomedical applications, e.g., as a multi-drug delivery platform. With this in view, reports of studies on the interaction between nanosized graphene oxide flakes and biological cells are beginning
Autor:
Angelo Mandarino, John J. Godleski, Loreilys Mejias Rivera, Hadley Witt, David Gregory, Brian W. LeBlanc, Alexey V. Fedulov, Connor C. McGuire
Publikováno v:
Environ Res
Talc and titanium dioxide are naturally occurring water-insoluble mined products usually available in the form of particulate matter. This study was prompted by epidemiological observations suggesting that perineal use of talc powder is associated wi
Autor:
William J. Britt, Wendi Zhou, Don J. Diamond, Zhongde Wang, Stephen J. Forman, C. La Rosa, John A. Zaia, Angelo Mandarino, Tumul Srivastava
Publikováno v:
Virology. 377(2):379-390
A therapeutic CMV vaccine incorporating an antigenic repertoire capable of eliciting a cellular immune response has yet to be successfully implemented for patients who already have acquired an infection. To address this problem, we have developed a v
Autor:
Anna Ivana Scovassi, L Rossi, Ennio Prosperi, I Frouin, C. Negri, R. Bernardi, M. Donzelli, A Bürkle, Angelo Mandarino
Publikováno v:
The Histochemical Journal. 29:831-837
Cell death by apoptosis was analysed in HeLa cells either treated with the antitumoral drug bleomycin or depleted of growth factors by long-term culture without medium change. The interference of apoptosis with normal cell cycle progression was follo
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 2, p e1002540 (2012)
PLoS Pathogens, Vol 8, Iss 2, p e1002540 (2012)
Herpes simplex virus type-1 (HSV-1) establishes latency in peripheral neurons, creating a permanent source of recurrent infections. The latent genome is assembled into chromatin and lytic cycle genes are silenced. Processes that orchestrate reentry i
Autor:
Kristina Abel, Peter A. Barry, Lisa Strelow, Don J. Diamond, Angelo Mandarino, Meghan K. Eberhardt, Zhongde Wang, Yujuan Yue, Kimberli A. Schmidt, Jinliang Li
Publikováno v:
Medical microbiology and immunology. 197(2)
A vaccine consisting of rhesus cytomegalovirus (RhCMV) pp65-2, gB and IE1 expressed via modified vaccinia Ankara (MVA) was evaluated in rhesus macaques with or without prior priming with expression plasmids for the same antigens. Following two MVA tr
Autor:
Angelo Mandarino, Francesco Frasca, Antonino Belfiore, Laura Sciacca, Roberta Malaguarnera, Rosa Linda Messina, Giuseppe Pandini, Riccardo Vigneri
Publikováno v:
The Journal of biological chemistry. 282(36)
c-Abl is a cytoplasmic tyrosine kinase involved in several signal transduction pathways. Here we report that c-Abl is involved also in insulin receptor signaling. Indeed, c-Abl tyrosine kinase is activated upon insulin stimulation. Inhibition of c-Ab