Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Angelo J. Gemma"'
Autor:
Jun Tian, Jonathan H. Chen, Sherry X. Chao, Karin Pelka, Marios Giannakis, Julian Hess, Kelly Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N. Allen, Thomas A. Abrams, Jeffrey W. Clark, Andrea C. Enzinger, Peter C. Enzinger, Samuel J. Klempner, Nadine J. McCleary, Jeffrey A. Meyerhardt, David P. Ryan, Matthew B. Yurgelun, Katie Kanter, Emily E. Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B. Bradford, Edmond Wong, Alexa G. Michel, Isobel J. Fetter, Giulia Siravegna, Angelo J. Gemma, Arlene Sharpe, Shadmehr Demehri, Rebecca Leary, Catarina D. Campbell, Omer Yilmaz, Gad A. Getz, Aparna R. Parikh, Nir Hacohen, Ryan B. Corcoran
Publikováno v:
Nature Medicine. 29:458-466
While BRAF inhibitor combinations with EGFR and/or MEK inhibitors have improved clinical efficacy in BRAFV600E colorectal cancer (CRC), response rates remain low and lack durability. Preclinical data suggest that BRAF/MAPK pathway inhibition may augm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4503ae8a502bac127cbff0a3ff92547
https://doi.org/10.1038/s41591-022-02181-8
https://doi.org/10.1038/s41591-022-02181-8
Autor:
Hui Zheng, Jennifer Y. Wo, Aparna Raj Parikh, Benjamin Greenbaum, Jeffrey W. Clark, Jasmin Joseph, Lawrence S. Blaszkowsky, Mihir Rajurkar, Alexander Solovyov, Ryan B. Corcoran, Emily E. Van Seventer, Jill N. Allen, Lipika Goyal, Theodore S. Hong, Eric Tai, David T. Ting, David P. Ryan, Vishal Thapar, Annamaria Szabolcs, Angelo J. Gemma
Publikováno v:
Journal of Clinical Oncology. 38:149-149
149 Background: Non-coding repeat RNAs in cancers are pervasive and “mimic” viruses with activation of pattern recognition receptors and the innate immune response. Many repeat RNAs replicate in cancer genomes through a reverse transcriptional in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::100dcac70da1a46ee976dbe004d34a88
https://doi.org/10.1200/jco.2020.38.4_suppl.149
https://doi.org/10.1200/jco.2020.38.4_suppl.149
Autor:
Angelo J. Gemma, Jill N. Allen, Andrew X. Zhu, James C. Cusack, Christine E. Eyler, Theodore S. Hong, Jeffrey W. Clark, Darrell R. Borger, David P. Ryan, Jennifer Y. Wo, Eunice L. Kwak, Harvey J. Mamon, David H. Berger, Paul C. Shellito, Lipika Goyal, Kevin M. Haigis, Hui Zheng, Henning Willers, David W. Rattner
Publikováno v:
Journal of Clinical Oncology. 36:e15674-e15674
e15674Background: RAS mutations confer radiation resistance in rectal cancer, with very low pCR rates, below 5%. Midostaurin is an oral, multi-target TKI, FDA-approved for FLT3 mutated leukemia, th...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103ed8c3aac96e5a54e80f99861d6745
https://doi.org/10.1200/jco.2018.36.15_suppl.e15674
https://doi.org/10.1200/jco.2018.36.15_suppl.e15674