Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Angelo Giacometti"'
Autor:
Federica Tonelli, Elisa Della Turca, Chiara Pecchini, Raffaele Longhi, Romano Di Fabio, Gian Paolo Vallerini, Matteo Biagetti, Dino Montanari, Angelo Giacometti, Anna Maria Capelli, Adelheid Roth, Angela Worby, Marco Mor, Emilio Merlo-Pich, Gabriele Costantino, Giorgio Bonanomi, Fabrizio Micheli, Luca Tarsi
Publikováno v:
ResearcherID
Autor:
Andrew J. Powell, SJ Medhurst, I Lago, YH Chen, Caterina Virginio, Elisa Ballini, A Buson, Laura Aldegheri, Wolfgang Jarolimek, Angelo Giacometti, Scott G. Summerfield, Corrado Carignani
Publikováno v:
British Journal of Pharmacology. 163:1315-1325
BACKGROUND AND PURPOSE P2X3 and P2X2/3 receptors are highly localized on the peripheral and central pathways of nociceptive signal transmission. The discovery of A-317491 allowed their validation as chronic inflammatory and neuropathic pain targets,
Autor:
Caterina Virginio, Angelo Giacometti, Georg C. Terstappen, Joseph M. Rimland, Laura Aldegheri
Publikováno v:
European Journal of Pharmacology. 445:153-161
The pharmacological properties of the rat alpha7 nicotinic acetylcholine receptor endogenously expressed in PC12 cells and recombinantly expressed in GH4C1 cells (alpha7-GH4C1 cells) were characterized and compared. Patch-clamp recordings demonstrate
Publikováno v:
SLAS Discovery. 5:255-261
For the identification of modulators of the metabotropic glutamate receptor mGluR7, a functional cell-based high throughput screening (HTS) assay was developed. This assay utilizes the signal transduction pathway of mGluR7, which is negatively couple
Autor:
Romano Di Fabio, Laura Zonzini, Giancarlo Merlo, Silvia Tomelleri, Alfredo Paio, Paola Zarantonello, Adelheid Roth, Federica Tonelli, Anna Maria Capelli, Angelo Giacometti, Elisa Moro, Emilio Merlo-Pich, Fabrizio Micheli
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(24)
A new class of selective NPS antagonist was developed starting from a commercially available product identified by screening activities. Experimental NMR observations and computational experiments allowed the discovery of a new class of derivatives.
Autor:
Manuela Bergamin, Emanuela Valentini, I. Maragno, Angelo Giacometti, Rosa Maria Gaion, Paola Dorigo
Publikováno v:
Cardiovascular Drugs and Therapy. 4:1477-1485
Muzolimine (10-500 microM) induced a concentration-dependent reduction of both the contractile force and frequency in spontaneously beating atria and in electrically driven left atrium from reserpine-treated guinea pigs. This negative inotropic respo
Autor:
Marcelo Rosato Siri, David Philip, Nicoletta Garbati, Simone Bertani, Angelo Giacometti, Nicola Fasdelli, Luciano Cunego, Mauro Corsi, Caterina Virginio, Laura Aldegheri, Cristiana Griffante, Philip Gerrard, Elisa Ballini
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e20