Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Angelo F. Borghetti"'
Autor:
Silvia La Monica, Angelo F. Borghetti, Paolo Soliani, Silvia Desenzani, Antonello A. Romani, Marina Morganti
Publikováno v:
Biochemical Pharmacology. 78:133-141
Cholangiocarcinoma is the second most common primary hepatic neoplasia and the only curative therapy is surgical resection or liver transplantation. Biphosphonates (BPs) are an emerging class of drugs widely used to treat bone diseases and also appea
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 68:74-81
This work was aimed at investigating a series of chitosan films obtained from chitosan, chitosan-phosphate, chitosan-phosphate-D-(+)raffinose or chitosan-phosphate-D-(+)sucrose solutions to preliminarily select a suitable biomaterial for developing a
Autor:
Angelo F. Borghetti, Roberta Alfieri, Claudia Fumarola, Domenica Carnicelli, Kenneth P. Wheeler, Giuseppe De Palma, Federica Vacondio, Pier Giorgio Petronini, Mara Bonelli, Maurizio Brigotti, Andrea Cavazzoni, Claudia Silva, Paola Mozzoni, Piero Sestili, Antonio Mutti
Publikováno v:
The Journal of Physiology. 576:391-401
Exposure of C2C12 muscle cells to hypertonic stress induced an increase in cell content of creatine transporter mRNA and of creatine transport activity, which peaked after about 24 h incubation at 0.45 osmol (kg H2O)−1. This induction of transport
Publikováno v:
Journal of Surgical Oncology. 93:446-455
Background and Objectives Angiogenesis is a complex multistep process that involves extracellular matrix remodeling, migration and proliferation of endothelial cells, and morphogenesis of microvessels. CD105 (endoglin), a co-receptor of the TGF-β su
Autor:
Pier Giorgio Petronini, Mara Bonelli, Andrea Cavazzoni, Kenneth P. Wheeler, Angelo F. Borghetti, Silvia Desenzani, Roberta Alfieri
Publikováno v:
The Journal of Physiology. 555:757-767
Studies of the responses of porcine pulmonary endothelial cells to acute hypertonic stress have been extended by examining the induction and underlying mechanisms of cell tolerance to both osmotic and heat stresses. Preliminary adaptation of these ce
Autor:
Domenica Carnicelli, Mara Bonelli, Roberta Alfieri, Pier Giorgio Petronini, Angelo F. Borghetti, Maurizio Brigotti, Kenneth P. Wheeler
Publikováno v:
Biochemical Journal. 369:369-374
To mimic what might happen in cells exposed to hypertonicity, the effects of increased osmolarity and ionic strength on cell-free protein synthesis have been examined. Translation of globin mRNA by rabbit reticulocyte lysate decreased by 30-60% when
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1592(2):135-140
Prolonged exposure of 3T3 cells to 0.5 osM hypertonic medium induced the accumulation of hsp70 mRNAs. This increase in mRNA levels required active protein synthesis. A weak and transient activation of heat shock factor 1 (HSF1) was noted, but it was
Autor:
Roberta Alfieri, Andrea Cavazzoni, Mara Bonelli, Kenneth P. Wheeler, Pier Giorgio Petronini, Angelo F. Borghetti, Alessandro E. Caccamo
Publikováno v:
The Journal of Physiology. 540:499-508
Porcine pulmonary arterial endothelial cells accumulated myo-inositol and taurine, as well as betaine, during adaptation to hypertonic stress. The cells grew and maintained their normal morphology during culture in hypertonic (0.5 osmol (kg H(2)O)(-1
Publikováno v:
Amino Acids. 20:363-380
In 3T3 cells temperatures higher than physiological stimulated amino acid transport activity in a dose-dependent manner up to 44 degrees C. However, the temperature increase did not induce widespread transport increase of all other nutrients tested.
Autor:
Angelo F. Borghetti, Mara Bonelli, Alessandro E. Caccamo, Kenneth P. Wheeler, P. G. Petronini, Andrea Cavazzoni, Roberta Alfieri
Publikováno v:
Biochemical and Biophysical Research Communications. 283:174-178
When porcine endothelial cells were exposed to hypertonicity, both the level of ATA2 (amino acid transporter 2) mRNA and activity of amino acid transport System A increased transiently, peaking after about 6 and 9 h, respectively. Cycloheximide, like