New Advances in Titanium-Mediated Free Radical Reactions

Autor: Carlo Punta, Angelo Clerici, Simona Prosperini, Nadia Pastori, Bianca Rossi

Publikováno v: Molecules, Vol 17, Iss 12, Pp 14700-14732 (2012)
Molecules

Titanium complexes have been widely used as catalysts for C‑C bond-forming processes via free-radical routes. Herein we provide an overview of some of the most significant contributions in the field, that covers the last decade, emphasizing the key

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e894232e710a4edacaa6ea96a9e18fb2
https://doi.org/10.3390/molecules171214700

TiCl3/PhN2+-mediated radical addition of ethers to aldimines generated in situ under aqueous conditions

Autor: Ombretta Porta, Walter Panzeri, Angelo Clerici, Rosalba Cannella, Nadia Patori, Eva Regolini

Publikováno v: Tetrahedron letters 46 (2005): 8351–8354. doi:10.1016/j.tetlet.2005.09.158
info:cnr-pdr/source/autori:Clerici A., Cannella R., Panzeri W., Pastori N., Regolini E., Porta O./titolo:TiCl3%2FPhN2+-mediated radical addition of ethers to aldimines generated in situ under aqueous conditions/doi:10.1016%2Fj.tetlet.2005.09.158/rivista:Tetrahedron letters/anno:2005/pagina_da:8351/pagina_a:8354/intervallo_pagine:8351–8354/volume:46

Ti(III)-mediated one-electron reduction of phenyldiazonium cation, followed by phenyl radical alpha-H atom abstraction from ethers, leads to one-pot radical addition of ethers to the C-atom of imines generated in situ from the corresponding aldehydes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247a6deb83a6d87aeae3e56425e367b1
https://doi.org/10.1016/j.tetlet.2005.09.158

Reactivity of Methyl Mandelate−Ti(IV)-enediolate: Oxidative Homocoupling versus Aldol and Direct Mannich-Type Syn-Diastereoselective Condensation

Autor: Angelo Clerici, Nadia Pastori, Ombretta Porta

Publikováno v: The Journal of Organic Chemistry. 70:4174-4176

[reaction: see text] Methyl mandelate undergoes quantitative oxidative homocoupling on treatment with TiCl4/amine at room temperature. In the presence of ArCHO, quantitative syn-diastereoselective aldol condensation takes over the dimerization, where

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a647d440cc7911bd6a04bce0338caa8
https://doi.org/10.1021/jo048279f

ChemInform Abstract: Free-Radical Hydroxymethylation of Ketimines Generated in situ: A One-Pot Multicomponent Synthesis of β,β-Disubstituted-β-aminoalcohols

Autor: Angelo Clerici, Carlo Punta, Bianca Rossi, Nadia Pastori

Publikováno v: ChemInform. 44

Oxidative radical addition of methanol and aromatic amines to simple aliphatic ketones offers a novel synthesis of β,β-disubstituted-β-aminoalcohols.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b10b7814ac14fae1068e14e5fafb023c
https://doi.org/10.1002/chin.201315054

On the paradox of TiCl4 reducing power: pinacol coupling and two-carbon homologation of carbonyl compounds

Autor: Angelo Clerici, Ombretta Porta, Nadia Pastori

Publikováno v: Tetrahedron Letters. 45:1825-1827

TiCl 4 /DIPEA/CH 2 Cl 2 reducing system promotes pinacol coupling and/or reduction to alcohol of aromatic aldehydes and carbonyl compounds activated towards reduction by an electron withdrawing group. In addition, bis homologation of these substrates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76875e8f34e2276b199cabf92809d8b5
https://doi.org/10.1016/j.tetlet.2004.01.025