Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angelo Casu"'
Autor:
M Paola Castelli, Camilla Madeddu, Alberto Casti, Angelo Casu, Paola Casti, Maria Scherma, Liana Fattore, Paola Fadda, M Grazia Ennas
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98079 (2014)
Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic ef
Externí odkaz:
https://doaj.org/article/901b4ea22f4742a4b3a34f1fdb600fa0
Autor:
Sean C. Godar, Jean C. Shih, M. Grazia Ennas, Marco Bortolato, Simone Tambaro, Kevin Chen, Angelo Casu, Alberto Casti, M. Paola Castelli
Publikováno v:
Journal of Psychiatric Research. 56:1-9
The termination of serotonin (5-hydroxytryptamine, 5-HT) neurotransmission is regulated by its uptake by the 5-HT transporter (5-HTT), as well as its degradation by monoamine oxidase (MAO)-A. MAO-A deficiency results in a wide set of behavioral alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fe2cd297cb6e72bf693496715c18ad
https://doi.org/10.1016/j.jpsychires.2014.04.014
https://doi.org/10.1016/j.jpsychires.2014.04.014
Autor:
Giovanna Flore, Maria Paola Castelli, Alessio Soggiu, Miriam Melis, Marco Bortolato, Paola Roncada, Andrea Urbani, Paola Devoto, Angelo Casu, Jc Shih, Sc Godar, Kevin Chen, Roberto Frau
Publikováno v:
Journal of Neuroscience. 32:8574-8582
Converging evidence shows that monoamine oxidase A (MAO A), the key enzyme catalyzing serotonin (5-hydroxytryptamine; 5-HT) and norepinephrine (NE) degradation, is a primary factor in the pathophysiology of antisocial and aggressive behavior. Accordi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dd0ccca139853474096a4552a3c74f
https://doi.org/10.1523/jneurosci.0225-12.2012
https://doi.org/10.1523/jneurosci.0225-12.2012
Autor:
P Casti, M. Paola Castelli, Maria Scherma, Angelo Casu, M. Grazia Ennas, Liana Fattore, Paola Fadda, Alberto Casti, Camilla Madeddu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e98079 (2014)
PLoS ONE, Vol 9, Iss 5, p e98079 (2014)
Methamphetamine (METH) is a potent psychostimulant with neurotoxic properties. Heavy use increases the activation of neuronal nitric oxide synthase (nNOS), production of peroxynitrites, microglia stimulation, and induces hyperthermia and anorectic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9348a4c6ece7c6b0a763afa63ea6bc2
https://pubmed.ncbi.nlm.nih.gov/24844285
https://pubmed.ncbi.nlm.nih.gov/24844285
Autor:
Carla Lobina, Giancarlo Colombo, Valentina Pedani, Alberto Casti, Gian Luigi Gessa, Stefania Lamponi, Maria Paola Castelli, Claudia Mugnaini, Federico Corelli, Maurizio Solinas, Angelo Casu, Daniela Giunta, Alessandra Porcu, Massimo Valoti, Stefania Dragoni, Paola Maccioni
Publikováno v:
Journal of medicinal chemistry (Online) 56 (2013): 3620–3635. doi:10.1021/jm400144w
info:cnr-pdr/source/autori:Claudia Mugnaini, Valentina Pedani, Angelo Casu, Carla Lobina, Alberto Casti, Paola Maccioni, Alessandra Porcu, Daniela Giunta, Stefania Lamponi, Maurizio Solinas, Stefania Dragoni, Massimo Valoti, Giancarlo Colombo, Maria Paola Castelli, Gian Luigi Gessa, Federico Corelli/titolo:Synthesis and Pharmacological Characterization of 2-(Acylamino)thiophene Derivatives as Metabolically Stable, Orally Effective, Positive Allosteric Modulators of the GABAB Receptor/doi:10.1021%2Fjm400144w/rivista:Journal of medicinal chemistry (Online)/anno:2013/pagina_da:3620/pagina_a:3635/intervallo_pagine:3620–3635/volume:56
info:cnr-pdr/source/autori:Claudia Mugnaini, Valentina Pedani, Angelo Casu, Carla Lobina, Alberto Casti, Paola Maccioni, Alessandra Porcu, Daniela Giunta, Stefania Lamponi, Maurizio Solinas, Stefania Dragoni, Massimo Valoti, Giancarlo Colombo, Maria Paola Castelli, Gian Luigi Gessa, Federico Corelli/titolo:Synthesis and Pharmacological Characterization of 2-(Acylamino)thiophene Derivatives as Metabolically Stable, Orally Effective, Positive Allosteric Modulators of the GABAB Receptor/doi:10.1021%2Fjm400144w/rivista:Journal of medicinal chemistry (Online)/anno:2013/pagina_da:3620/pagina_a:3635/intervallo_pagine:3620–3635/volume:56
Two recently reported hit compounds, COR627 and COR628, underpinned the development of a series of 2-(acylamino)thiophene derivatives. Some of these compounds displayed significant activity in vitro as positive allosteric modulators of the GABAB rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7c61378e47961e694af15f6da1c0a5
https://pubmed.ncbi.nlm.nih.gov/23544432
https://pubmed.ncbi.nlm.nih.gov/23544432
Regional distribution of 5α-reductase type 2 in the adult rat brain: an immunohistochemical analysis
Autor:
Saturnino Spiga, Marco Bortolato, Angelo Casu, Roberto Frau, M. Paola Castelli, Maria Grazia Ennas, Alberto Casti
Publikováno v:
Psychoneuroendocrinology. 38(2)
The enzyme 5α-reductase (5αR) catalyzes the conversion of testosterone and other Δ(4)-3-ketosteroids into their 5α-reduced metabolites. Of the five members of the 5αR family, the type 2 enzyme (5αR2) plays a key role in androgen metabolism, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db76632cfa1cb78545b57f90e2747ad
https://pubmed.ncbi.nlm.nih.gov/22776423
https://pubmed.ncbi.nlm.nih.gov/22776423
Autor:
Giancarlo Colombo, Federico Corelli, Simone Brogi, Mauro A.M. Carai, Maurizio Solinas, Angelo Casu, Andrea Tafi, Gian Luigi Gessa, Maria Paola Castelli, Serena Pasquini, Daniela Giunta, Claudia Mugnaini, Carla Lobina, P Casti
Publikováno v:
The journal of pharmacology and experimental therapeutics (Online) (2012): 529–538.
info:cnr-pdr/source/autori:M. Paola Castelli; Angelo Casu; Paola Casti; Carla Lobina; Mauro A. M. Carai; Giancarlo Colombo; Maurizio Solinas; Daniela Giunta; Claudia Mugnaini; Serena Pasquini; Andrea Tafi; Simone Brogi; Gian Luigi Gessa; Federico Corelli/titolo:Characterization of COR627 and COR628, Two Novel Positive Allosteric Modulators of the GABAB Receptor/doi:/rivista:The journal of pharmacology and experimental therapeutics (Online)/anno:2012/pagina_da:529/pagina_a:538/intervallo_pagine:529–538/volume
info:cnr-pdr/source/autori:M. Paola Castelli; Angelo Casu; Paola Casti; Carla Lobina; Mauro A. M. Carai; Giancarlo Colombo; Maurizio Solinas; Daniela Giunta; Claudia Mugnaini; Serena Pasquini; Andrea Tafi; Simone Brogi; Gian Luigi Gessa; Federico Corelli/titolo:Characterization of COR627 and COR628, Two Novel Positive Allosteric Modulators of the GABAB Receptor/doi:/rivista:The journal of pharmacology and experimental therapeutics (Online)/anno:2012/pagina_da:529/pagina_a:538/intervallo_pagine:529–538/volume
The potential efficacy of GABA(B) receptor agonists in the treatment of pain, drug addiction, epilepsy, cognitive dysfunctions, and anxiety disorders is supported by extensive preclinical and clinical evidence. However, the numerous side effects prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d4b356c262e231f1dd62e28be84608
https://publications.cnr.it/doc/181553
https://publications.cnr.it/doc/181553
Publikováno v:
The 17th European Symposium on Organic Chemistry (ESOC 2011), 2011
info:cnr-pdr/source/autori:Daniela Giunta; Maria Paola Castelli; Angelo Casu; Gian Luigi Gessa; Maurizio Solinas/congresso_nome:The 17th European Symposium on Organic Chemistry (ESOC 2011)/congresso_luogo:/congresso_data:2011/anno:2011/pagina_da:/pagina_a:/intervallo_pagine
info:cnr-pdr/source/autori:Daniela Giunta; Maria Paola Castelli; Angelo Casu; Gian Luigi Gessa; Maurizio Solinas/congresso_nome:The 17th European Symposium on Organic Chemistry (ESOC 2011)/congresso_luogo:/congresso_data:2011/anno:2011/pagina_da:/pagina_a:/intervallo_pagine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=cnr_________::6f696749d590e8db3c041189510a9d46
https://publications.cnr.it/doc/181583
https://publications.cnr.it/doc/181583