Tolerability of vortioxetine compared to selective serotonin reuptake inhibitors in older adults with major depressive disorder (VESPA): a randomised, assessor-blinded and statistician-blinded, multicentre, superiority trialResearch in context

Autor: Giovanni Ostuzzi, Chiara Gastaldon, Mauro Tettamanti, Massimo Cartabia, Igor Monti, Andrea Aguglia, Eugenio Aguglia, Francesco Bartoli, Camilla Callegari, Andrea Canozzi, Elvira Anna Carbone, Giuseppe Carrà, Rosangela Caruso, Simone Cavallotti, Stefania Chiappini, Fabrizio Colasante, Beatrice Compri, Armando D'Agostino, Pasquale De Fazio, Renato de Filippis, Matteo Gari, Marta Ielmini, Gianmarco Ingrosso, Silvia Mammarella, Giovanni Martinotti, Alessandro Rodolico, Rita Roncone, Enrico Sterzi, Lorenzo Tarsitani, Elisa Tiberto, Liliana Todini, Francesco Amaddeo, Barbara D'Avanzo, Angelo Barbato, Corrado Barbui, Maria Chiara Alessi, Gabriele Avincola, Bianca Bachi, Gianna Bernasconi, Andrea Birgillito, Emanuele Bisso, Stefano Bonora, Angela Calabrese, Tommaso Callovini, Aurelia Canestro, Salvo Canonico, Chiara Alessandro Capogrosso, Elvira Carbone, Doriana Carosielli, Ivano Caselli, Daniele Cavaleri, Clara Cavallotto, Marco Cesca, Cecilia Chiarenza, Riccardo Matteo Cioni, Sara Coloccini, Marco Cruciata, Claudia Cumerlato, Renato De Filippis, Manuela De Palma, Sasha Del Vecchio, Bianca Della Rocca, Chiara Di Natale, Ettore D'Onofrio, Irene Espa, Giulia Fior, Marta Gancitano, Barbara Giordano, Laura Giusti, Luigi Grassi, Pierluca Guzzi, Celeste Isella, Annamaria Lax, Leonardo Marano, Federico Marconi, Marco Marella, Alessia Metelli, Giulia Michencig, Andrea Miuli, Alessandro Moncada, Pietro Morello, Federico Moretti, Marco Morreale, Alessio Mosca, Christian Nasti, Michela Nosé, Filippo Ogheri, Margherita Oresti, Alessandra Ornaghi, Dario Palpella, Corinna Pancheri, Davide Papola, Silvia Passeri, Mauro Pettorusso, Susanna Piacenti, Irene Pinucci, Valentina Pugliese, Marianna Purgato, Marianna Rania, Federica Robbi, Samantha Romito, Barbara Ronchi, Valentina Roselli, Cristina Segura-Garcia, Maria Salvina Signorelli, Gabriele Simonelli, Antonella Sociali, Serena Sturiale, Antonio Tambelli, Beatrice Todesco, Alice Trabucco, Giulia Turrini, Veronica Villa, Federico Wiedenmann, Luca Zambuto, Elisa Zanini, Chiara Zannini, Luigi Zerbinati

Publikováno v: EClinicalMedicine, Vol 69, Iss , Pp 102491- (2024)

Summary: Background: Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such a vulne

Externí odkaz: https://doaj.org/article/b6d9532a29514d6885cce2880822f39b

Using big data and Population Health Management to assess care and costs for patients with severe mental disorders and move toward a value-based payment system

Autor: Valeria D. Tozzi, Helen Banks, Lucia Ferrara, Angelo Barbato, Giovanni Corrao, Barbara D’avanzo, Teresa Di Fiandra, Andrea Gaddini, Matteo Monzio Compagnoni, Michele Sanza, Alessio Saponaro, Salvatore Scondotto, Antonio Lora

Publikováno v: BMC Health Services Research, Vol 23, Iss 1, Pp 1-14 (2023)

Abstract Background Mental health (MH) care often exhibits uneven quality and poor coordination of physical and MH needs, especially for patients with severe mental disorders. This study tests a Population Health Management (PHM) approach to identify

Externí odkaz: https://doaj.org/article/7e9d7960635a4e15be0ef414fe2f12c0

From contact coverage to effective coverage of community care for patients with severe mental disorders: A real-world investigation from Italy

Autor: Giovanni Corrao, Matteo Monzio Compagnoni, Angelo Barbato, Barbara D’Avanzo, Teresa Di Fiandra, Lucia Ferrara, Andrea Gaddini, Alessio Saponaro, Salvatore Scondotto, Valeria D. Tozzi, Flavia Carle, Simona Carbone, Daniel H. Chisholm, Antonio Lora

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

ObjectivesTo measure the gap between contact and effective coverage of mental healthcare (MHC).Materials and methods45,761 newly referred cases of depression, schizophrenia, bipolar disorder, and personality disorder from four Italian regions were in

Externí odkaz: https://doaj.org/article/ba557aeaf8564c61b58d4f466f0d7a0b

Prevalence and course of disease after lung resection in primary ciliary dyskinesia: a cohort & nested case-control study

Autor: Panayiotis Kouis, Myrofora Goutaki, Florian S. Halbeisen, Ifigeneia Gioti, Nicos Middleton, Israel Amirav, on behalf of the Israeli PCD Consortium, Angelo Barbato, on behalf of the Italian PCD Consortium, Laura Behan, Mieke Boon, Nagehan Emiralioglu, Eric G. Haarman, Bulent Karadag, Cordula Koerner-Rettberg, Romain Lazor, on behalf of the Swiss PCD Group, Michael R. Loebinger, Bernard Maitre, on behalf of the French Reference Centre for Rare Lung Diseases, Henryk Mazurek, Lucy Morgan, Kim Gjerum Nielsen, Heymut Omran, Ugur Özçelik, Mareike Price, Andrzej Pogorzelski, Deborah Snijders, on behalf of the PCD Italian Consortium, Guillaume Thouvenin, Claudius Werner, Zorica Zivkovic, Claudia E. Kuehni, Panayiotis K. Yiallouros

Publikováno v: Respiratory Research, Vol 20, Iss 1, Pp 1-12 (2019)

Abstract Background Lung resection is a controversial and understudied therapeutic modality in Primary Ciliary Dyskinesia (PCD). We assessed the prevalence of lung resection in PCD across countries and compared disease course in lobectomised and non-

Externí odkaz: https://doaj.org/article/c428f64b0b3e41d1a14ad10bef7262ea

The effectiveness of measles-mumps-rubella (MMR) vaccination in the prevention of pediatric hospitalizations for targeted and untargeted infections: A retrospective cohort study

Autor: Giuseppe La Torre, Rosella Saulle, Brigid Unim, Angela Meggiolaro, Angelo Barbato, Alice Mannocci, Antonietta Spadea

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 13, Iss 8, Pp 1879-1883 (2017)

Objectives: To evaluate the effectiveness of the measles-mumps-rubella (MMR) vaccine in reducing hospitalizations for infectious disease, targeted and not targeted, as well as from respiratory diseases in children in Rome. Methods: The cohort was rec

Externí odkaz: https://doaj.org/article/1684a53638764eeaaf4c6bd32de44575