Výsledky vyhledávání - "Angelo A, Cardoso"

Akademický článek

Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium

Autor: Young-Woong Kim, Greta Zara, HyunJun Kang, Sergio Branciamore, Denis O’Meally, Yuxin Feng, Chia-Yi Kuan, Yingjun Luo, Michael S. Nelson, Alex B. Brummer, Russell Rockne, Zhen Bouman Chen, Yi Zheng, Angelo A. Cardoso, Nadia Carlesso

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

Here Kim et al. show that primary BMECs can be maintained ex vivo as distinct sinusoidal- and arterial-like populations and that the presence of macrophages is critical to preserve their native transcriptomic profiles and functional heterogeneity.

Externí odkaz: https://doaj.org/article/9ee80c4c324443f1b1bf968f84b4c61f

Zobrazit plný text záznamu

Akademický článek

Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 344-359 (2022)

T cells engineered to express HIV-specific chimeric antigen receptors (CARs) represent a promising strategy to clear HIV-infected cells, but to date have not achieved clinical benefits. A likely hurdle is the limited T cell activation and persistence

Externí odkaz: https://doaj.org/article/c35d7761f02247f9aa1379d906dc6325

Zobrazit plný text záznamu

Akademický článek

Engineered extracellular vesicles directed to the spike protein inhibit SARS-CoV-2

Autor: Tristan A. Scott, Aroon Supramaniam, Adi Idris, Angelo A. Cardoso, Surya Shrivastava, Gabrielle Kelly, Nicole A. Grepo, Citradewi Soemardy, Roslyn M. Ray, Nigel A.J. McMillan, Kevin V. Morris

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 355-366 (2022)

SARS-CoV-2 (CoV-2) viral infection results in COVID-19 disease, which has caused significant morbidity and mortality worldwide. A vaccine is crucial to curtail the spread of SARS-CoV-2, while therapeutics will be required to treat ongoing and reemerg

Externí odkaz: https://doaj.org/article/e0be4145231641698c313c54ca4c5a8c

Zobrazit plný text záznamu

Akademický článek

COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins

Publikováno v: Cell Reports, Vol 40, Iss 1, Pp 111022- (2022)

Summary: The COVID-19 pandemic has triggered the first widespread vaccination campaign against a coronavirus. Many vaccinated subjects are previously naive to SARS-CoV-2; however, almost all have previously encountered other coronaviruses (CoVs), and

Externí odkaz: https://doaj.org/article/f31c9ede1fc74a5a94d3651849a3547f

Zobrazit plný text záznamu

Akademický článek

The Earliest T-Precursors in the Mouse Embryo Are Susceptible to Leukemic Transformation

Autor: Jixin Ding, Angelo A. Cardoso, Momoko Yoshimoto, Michihiro Kobayashi

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Acute lymphoblastic leukemia (ALL) is the most common malignancy in pediatric patients. About 10–15% of pediatric ALL belong to T-cell ALL (T-ALL), which is characterized by aggressive expansion of immature T-lymphoblasts and is categorized as high

Externí odkaz: https://doaj.org/article/df58b5edfe1145e9bc7980cb0c423161

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání