Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Angelo, Willems"'
Autor:
Karin Vanderkerken, Medicherla, S., Les Coulton, Hendrik De Raeve, Angelo Willems, Lawson, M., Benjamin Van Camp, Protter, A. A., Higgins, L. S., Eline Menu, Croucher, Peter I.
Publikováno v:
Vrije Universiteit Brussel
The bone microenvironment (BM) plays a critical role in supporting the growth and survival of multiple myeloma (MM) as well as in the development of osteolytic bone disease. Signaling through p38±MAPK mediates synthesis of MM cell growth factors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cde64d28b6c7707a58c8915db9b99717
https://hdl.handle.net/20.500.14017/965792a4-1c26-43d9-909c-b4de6763d87a
https://hdl.handle.net/20.500.14017/965792a4-1c26-43d9-909c-b4de6763d87a
Autor:
Michelle A. Lawson, Angelo Willems, Andrew A. Protter, Eline Menu, Linda S. Higgins, Ben Van Camp, Peter I. Croucher, Satya Medicherla, Karin Vanderkerken, Hendrik De Raeve, Les Coulton
Publikováno v:
Cancer research
The bone microenvironment plays a critical role in supporting the growth and survival of multiple myeloma as well as in the development of osteolytic bone disease. Signaling through p38α mitogen-activated protein kinase (MAPK) mediates synthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c261bad57c920a77f8784c2ca1e469c4
https://hdl.handle.net/10067/647440151162165141
https://hdl.handle.net/10067/647440151162165141
Autor:
Karin, Vanderkerken, Kewal, Asosingh, Angelo, Willems, Hendrik, De Raeve, Pedro, Couck, Frans, Gorus, Peter, Croucher, Ben, Van Camp
Publikováno v:
Methods in molecular medicine. 113
Multiple myeloma is a B-cell neoplasm characterized by the monoclonal proliferation of plasma cells in the bone marrow, the development of osteolytic lesions, and the induction of angiogenesis. These different processes require three-dimensional inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cde4f638ae7efbb44d26c69486d11b7
https://pubmed.ncbi.nlm.nih.gov/15968104
https://pubmed.ncbi.nlm.nih.gov/15968104
Autor:
Kewal Asosingh, Hendrik De Raeve, Frans Gorus, Peter I. Croucher, Angelo Willems, Ben Van Camp, Pedro Couck, Karin Vanderkerken
Multiple myeloma is a B-cell neoplasm characterized by the monoclonal proliferation of plasma cells in the bone marrow, the development of osteolytic lesions, and the induction of angiogenesis. These different processes require three-dimensional inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a1adb966b2ad0c938e19070bcd395b
https://doi.org/10.1385/1-59259-916-8:191
https://doi.org/10.1385/1-59259-916-8:191
Autor:
Karin, Vanderkerken, Evy, De Leenheer, Claire, Shipman, Kewal, Asosingh, Angelo, Willems, Ben, Van Camp, Peter, Croucher
Publikováno v:
Cancer research. 63(2)
The aim of the present study was to determine whether modifying the local bone environment with osteoprotegerin (OPG), the soluble decoy receptor for receptor activator of nuclear factor-kappaB (RANK) ligand, could affect tumor burden and survival in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56962a596c2332ee31d285b43a46f0ce
https://pubmed.ncbi.nlm.nih.gov/12543775
https://pubmed.ncbi.nlm.nih.gov/12543775
Publikováno v:
Vrije Universiteit Brussel
Both CD45(+) and CD45(-) multiple myeloma (MM) cells are observed in the bone marrow (BM) of MM patients; however, their impact on the outcome of the disease is unknown. Most (92%) of the mice injected with murine 5T2MM cells develop myeloma in 10-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b5745d61025ebbe1338266b8842a88e6
https://hdl.handle.net/20.500.14017/4fac2317-ff9e-4391-9738-7f71143c8db6
https://hdl.handle.net/20.500.14017/4fac2317-ff9e-4391-9738-7f71143c8db6
Autor:
Karin Vanderkerken, Leenheer, E., Shipman, Claire M., Kewal Asosingh, Angelo Willems, Benjamin Van Camp, Croucher, Peter I.
Publikováno v:
Scopus-Elsevier
ResearcherID
Europe PubMed Central
Vrije Universiteit Brussel
ResearcherID
Europe PubMed Central
Vrije Universiteit Brussel
The aim of the present study was to determine whether modifying the local bone environment with osteoprotegerin (OPG), the soluble decoy receptor for receptor activator of nuclear factor-kappaB (RANK) ligand, could affect tumor burden and survival in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::030113026fa007979a22f52993dde3df
https://biblio.vub.ac.be/vubir/recombinant-osteoprotegerin-decreases-tumor-burden-and-increases-survival-in-a-murine-model-of-multiple-myeloma(f6f8a6da-a971-485f-80dc-d45fc7d32a32).html
https://biblio.vub.ac.be/vubir/recombinant-osteoprotegerin-decreases-tumor-burden-and-increases-survival-in-a-murine-model-of-multiple-myeloma(f6f8a6da-a971-485f-80dc-d45fc7d32a32).html
Autor:
Ivan Van Riet, Guy Storme, Hendrik De Raeve, Kewal Asosingh, Benjamin Van Camp, Mark De Ridder, Karin Vanderkerken, Angelo Willems
Publikováno v:
Blood. 104:2348-2348
Recently we reported that pre-clinical myeloma disease progression in the 5T2MM mouse model is characterized by predominant CD45+ MM-cells in the early, pre-angiogenic stage stage of slow tumor progression, followed by expansion of CD45− MM-cells d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad1a905407eb8117970aabbfd3df2d5
https://doi.org/10.1182/blood.v104.11.2348.2348
https://doi.org/10.1182/blood.v104.11.2348.2348
Autor:
Kewal Asosingh, Hendrik De Raeve, Mark De Ridder, Guy Storme, Angelo Willems, Ivan Van Riet, Benjamin Van Camp, Karin Vanderkerken
Publikováno v:
Vrije Universiteit Brussel
BACKGROUND AND OBJECTIVES: Unlike most other tumors, multiple myeloma (MM) cells have to survive and to grow in a bone marrow (BM) microenvironment which is already hypoxic by nature. BM hypoxia is crucial for normal hematopoiesis. However, how BM hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5245cac1e5d8c9a7fb1eabc06f6b6782
https://researchportal.vub.be/en/publications/a5366707-492a-47ab-8ecc-2508eec61495
https://researchportal.vub.be/en/publications/a5366707-492a-47ab-8ecc-2508eec61495