Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Angelo, Frei"'
Autor:
José L. Medina-Franco, Edgar López-López, Emma Andrade, Lena Ruiz-Azuara, Angelo Frei, Davy Guan, Johannes Zuegg, Mark A.T. Blaskovich
Publikováno v:
Drug Discovery Today. 27:1420-1430
Metallodrug discovery has evolved in recent years, yielding several compounds in the clinic for therapeutic and medical imaging diagnostic applications. As reviewed here, several research groups in well-established medicinal inorganic chemistry group
Autor:
Angelo Frei, Annick Van Niekerk, Cassiem M. Joseph, Angela Kavanagh, Hue Dinh, Andrew J. Swarts, Selwyn F. Mapolie, Johannes Zuegg, Amy K. Cain, Alysha G. Elliott, Mark A. T. Blaskovich
Infections associated with antimicrobial resistance (AMR) are poised to become the leading cause of death in the next few decades, a scenario that can be ascribed to two phenomena: antibiotic over-prescription and a lack of antibiotic drug developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f2b7384889d54aee89977eeddf3fe70
https://doi.org/10.26434/chemrxiv-2023-j4fg9
https://doi.org/10.26434/chemrxiv-2023-j4fg9
Publikováno v:
Dalton Transactions. 51:9039-9048
The synthesis and characterisation of a series of Kryptofix 222-based chelators that can be radiolabelled with 201Tl(i) in high radiochemical yields at ambient temperature are described.
Synthesis and anti-microbial activity of a new series of bis(diphosphine) rhenium(v ) dioxo complexes
Autor:
Saul M. Cooper, Christina Siakalli, Andrew J. P. White, Angelo Frei, Philip W. Miller, Nicholas J. Long
Publikováno v:
Dalton Transactions. 51:12791-12795
Rhenium-based metallodrugs have recently been highlighted as promising candidates for new antibiotics to combat multi-drug resistant (MDR) pathogens. A new class of rhenium(V) dioxo complexes were prepared from readily accessible diphosphine ligands,
Autor:
Angelo Frei, Alysha G. Elliott, Alex Kan, Hue Dinh, Stefan Braese, Alice E. Bruce, Mitchell R. Bruce, Feng Chen, Dhirgam Humaidy, Nicole Jung, A. Paden King, Peter G. Lye, Hanna K. Maliszewska, Ahmed M. Mansour, Dimitris Matiadis, María Paz Muñoz, Tsung-Yu Pai, Shyam Pokhrel, Peter J. Sadler, Marina Sagnou, Michelle Taylor, Justin J. Wilson, Dean Woods, Johannes Zuegg, Wieland Meyer, Amy K. Cain, Matthew A. Cooper, Mark A. T. Blaskovich
There are currently fewer than ten antifungal drugs in clinical development, but new fungal strains, which are resistant to most current antifungals are spreading rapidly across the world. To prevent a second resistance crisis, new classes of antifun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197d3e4d3cc18221c5be926106578341
https://ueaeprints.uea.ac.uk/id/eprint/87077/
https://ueaeprints.uea.ac.uk/id/eprint/87077/
Autor:
Angelo Frei
Publikováno v:
Antibiotics, Vol 9, Iss 2, p 90 (2020)
With the widespread rise of antimicrobial resistance, most traditional sources for new drug compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal complexes have long had only a niche presence in the medicinal chemi
Externí odkaz:
https://doaj.org/article/4905c74c290f4a4f8e67c4edb11ec36f
Autor:
Angelo, Frei, Alysha G, Elliott, Alex, Kan, Hue, Dinh, Stefan, Bräse, Alice E, Bruce, Mitchell R, Bruce, Feng, Chen, Dhirgam, Humaidy, Nicole, Jung, A Paden, King, Peter G, Lye, Hanna K, Maliszewska, Ahmed M, Mansour, Dimitris, Matiadis, María Paz, Muñoz, Tsung-Yu, Pai, Shyam, Pokhrel, Peter J, Sadler, Marina, Sagnou, Michelle, Taylor, Justin J, Wilson, Dean, Woods, Johannes, Zuegg, Wieland, Meyer, Amy K, Cain, Matthew A, Cooper, Mark A T, Blaskovich
Publikováno v:
JACS Au
[Image: see text] There are currently fewer than 10 antifungal drugs in clinical development, but new fungal strains that are resistant to most current antifungals are spreading rapidly across the world. To prevent a second resistance crisis, new cla
Publikováno v:
Dalton Transactions. 50:17506-17514
A novel proof-of-concept is reported to modify the water solubility and potential biological effects of a bis(diphenylphosphino)alkylamine (PNP) ligand and the corresponding metal complex, by introducing an amine group on the outer periphery of the p
Autor:
Andreas Roodt, Marietjie Schutte-Smtih, Alice Brink, Dumisani V. Kama, Roger Alberto, Henrik Braband, Chantel W. Swart, Angelo Frei
Publikováno v:
New Journal of Chemistry. 45:22141-22149
Two bidentate PNP ligands N,N-bis(di-p-tolylphosphino)cyclohexylamine (Cy-pTolPNP) (1) and N,N-bis(di-p-tolylphosphino)cyclobutylamine (Cb-pTolPNP) (2) were synthesized and crystallized. Coordination to the fac-[MI(CO)3]+ core (M = Re, 99Tc) yielded
Autor:
Mario Krenn, Qianxiang Ai, Senja Barthel, Nessa Carson, Angelo Frei, Nathan C. Frey, Pascal Friederich, Théophile Gaudin, Alberto Alexander Gayle, Kevin Maik Jablonka, Rafael F. Lameiro, Dominik Lemm, Alston Lo, Seyed Mohamad Moosavi, José Manuel Nápoles-Duarte, AkshatKumar Nigam, Robert Pollice, Kohulan Rajan, Ulrich Schatzschneider, Philippe Schwaller, Marta Skreta, Berend Smit, Felix Strieth-Kalthoff, Chong Sun, Gary Tom, Guido Falk von Rudorff, Andrew Wang, Andrew D. White, Adamo Young, Rose Yu, Alán Aspuru-Guzik
Publikováno v:
Patterns (New York, N.Y.), vol 3, iss 10
Krenn, M, Ai, Q, Barthel, S, Carson, N, Frei, A, Frey, N C, Friederich, P, Gaudin, T, Gayle, A A, Jablonka, K M, Lameiro, R F, Lemm, D, Lo, A, Moosavi, S M, Nápoles-Duarte, J M, Nigam, A K, Pollice, R, Rajan, K, Schatzschneider, U, Schwaller, P, Skreta, M, Smit, B, Strieth-Kalthoff, F, Sun, C, Tom, G, Falk von Rudorff, G, Wang, A, White, A D, Young, A, Yu, R & Aspuru-Guzik, A 2022, ' SELFIES and the future of molecular string representations ', Patterns, vol. 3, no. 10, 100588, pp. 1-27 . https://doi.org/10.1016/j.patter.2022.100588
Patterns, 3 (10), Art.-Nr.: 100588
Patterns, 3(10):100588, 1-27. Cell Press
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Patterns
Krenn, M, Ai, Q, Barthel, S, Carson, N, Frei, A, Frey, N C, Friederich, P, Gaudin, T, Gayle, A A, Jablonka, K M, Lameiro, R F, Lemm, D, Lo, A, Moosavi, S M, Nápoles-Duarte, J M, Nigam, A K, Pollice, R, Rajan, K, Schatzschneider, U, Schwaller, P, Skreta, M, Smit, B, Strieth-Kalthoff, F, Sun, C, Tom, G, Falk von Rudorff, G, Wang, A, White, A D, Young, A, Yu, R & Aspuru-Guzik, A 2022, ' SELFIES and the future of molecular string representations ', Patterns, vol. 3, no. 10, 100588, pp. 1-27 . https://doi.org/10.1016/j.patter.2022.100588
Patterns, 3 (10), Art.-Nr.: 100588
Patterns, 3(10):100588, 1-27. Cell Press
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Patterns
Artificial intelligence (AI) and machine learning (ML) are expanding in popularity for broad applications to challenging tasks in chemistry and materials science. Examples include the prediction of properties, the discovery of new reaction pathways,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6c0f1681cc8bcc1e6b205948386b65