Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Angelita Poziello"'
Autor:
Angelita Poziello, Angela Nebbioso, Hendrik G. Stunnenberg, Joost H.A. Martens, Vincenzo Carafa, Lucia Altucci
Publikováno v:
Epigenetics, Vol 16, Iss 8, Pp 838-850 (2021)
Acetylation of histone and non-histone proteins is a post-translational modification mostly associated with activation of gene transcription. The first histone acetyltransferase (HAT) identified as modifying newly synthesized histone H4 in yeast was
Externí odkaz:
https://doaj.org/article/2163b107ca3d4a5d8ba88f2dbb9cd4e6
Autor:
Angelita Poziello, Angela Nebbioso, Hendrik G. Stunnenberg, Joost H. A. Martens, Lucia Altucci, Vincenzo Carafa
Introduction: Acetylation of histone and non-histone proteins is a post-translational modification mostly associated with activation of gene transcription. The first histone acetyltransferase (HAT) identified as modifying newly synthesized histone H4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3977::03db7b7edb394bb09ae28f00a2e945e7
http://hdl.handle.net/11591/434104
http://hdl.handle.net/11591/434104
Autor:
Takashi Kurohara, Piyush Gediya, Varalakshmi Raguraman, Debarpan Ghosh, Manjunath Ghate, Lucia Altucci, Vincenzo Carafa, Nikum D. Sitwala, Vinod Sanna, K. Suthindhiran, Angelita Poziello, Laura Della Torre, Dhiraj Bhatia, Takayoshi Suzuki, Vivek K. Vyas
Publikováno v:
Bioorganic chemistry. 110
The discovery and development of isoform-selective histone deacetylase (HDAC) inhibitor is a challenging task because of the sequence homology among HDAC enzymes. In the present work, novel tetrahydro benzo[b]thiophene-3-carbonitrile based benzamides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdaffa6b43b33a9dcabbdd92a57c5a2
https://pubmed.ncbi.nlm.nih.gov/33756235
https://pubmed.ncbi.nlm.nih.gov/33756235
Autor:
Hendrik G. Stunnenberg, Lucia Altucci, Joost H.A. Martens, Angela Nebbioso, Angelita Poziello, Vincenzo Carafa
Publikováno v:
Epigenetics
Epigenetics, 16, 8, pp. 838-850
Epigenetics, 16, 838-850
Epigenetics, 16, 8, pp. 838-850
Epigenetics, 16, 838-850
Acetylation of histone and non-histone proteins is a post-translational modification mostly associated with activation of gene transcription. The first histone acetyltransferase (HAT) identified as modifying newly synthesized histone H4 in yeast was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5daff168d1db003779137d3c8324b35
http://hdl.handle.net/11591/434804
http://hdl.handle.net/11591/434804
Autor:
Laura Della Torre, Angelita Poziello, Federica Sarno, Alessandro Paiardini, Antonello Mai, Dante Rotili, Angela Nebbioso, Lucia Altucci, Vincenzo Carafa
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 23
Programmed cell death (PCD) is a fundamental process involved in animal development and in maintaining cellular homeostasis...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450f50179d7db7289efe8362e592bbf1
https://doi.org/10.26717/bjstr.2019.23.003920
https://doi.org/10.26717/bjstr.2019.23.003920
Autor:
Marzia Di Donato, Daniela Tomaselli, Dante Rotili, Angela Nebbioso, Lucia Altucci, Alfonso Baldi, Gabriella Castoria, Elham Safadeh, Zhijun Yu, Pia Giovannelli, Angelita Poziello, Laura Della Torre, Antonello Mai, Vincenzo Carafa
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 22
Volume 20
Issue 22
Sirtuins, a family of nicotinamide adenine dinucleotide (NAD+)-dependent lysine deacetylases, are promising targets for anticancer treatment. Recently, we characterized a novel pan-sirtuin (SIRT) inhibitor, MC2494, displaying antiproliferative effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782fe2eb21747c99ee3ba3e58496d36b
http://hdl.handle.net/11591/420028
http://hdl.handle.net/11591/420028
Autor:
Maria Vittoria Cubellis, Angelita Poziello, Israel Cabeza de Vaca, Giuseppina Andreotti, Victor Guallar, Maria Chiara Monti
Publikováno v:
Journal of Biological Chemistry. 289:34900-34910
The most common glycosylation disorder is caused by mutations in the gene encoding phosphomannomutase2, producing a disease still without a cure. Phosphomannomutase2, a homodimer in which each chain is composed of two domains, requires a bisphosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b6c904f313dfa19d2d8c94a4773bd8
https://doi.org/10.1074/jbc.m114.586362
https://doi.org/10.1074/jbc.m114.586362
Publikováno v:
info:cnr-pdr/source/autori:Giuseppina Andreotti (1), Angelita Poziello (1), Maria Vittoria Cubellis (2,3)/congresso_nome:10th International Conference on Protein Stabilization/congresso_luogo:Stresa/congresso_data:7-9 maggio 2014/anno:2014/pagina_da:/pagina_a:/intervallo_pagine
A good share of all the mutations associated with human diseases cause mild protein destabilization. Drugs known as "pharmacological chaperones" can stabilize these mutants and rescue their activity. Given a gene, some mutations respond, others do no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=cnr_________::cc6dc14c823fef1a5ae06b198be38b18
http://www.cnr.it/prodotto/i/281101
http://www.cnr.it/prodotto/i/281101