Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Angelique Hölzemer"'
Autor:
Klara Klein, Angelique Hölzemer, Tim Wang, Tae-Eun Kim, Haley L. Dugan, Stephanie Jost, Marcus Altfeld, Wilfredo F. Garcia-Beltran
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
While human leukocyte antigen (HLA) and HLA-like proteins comprise an overwhelming majority of known ligands for NK-cell receptors, the interactions of NK-cell receptors with non-conventional ligands, particularly carbohydrate antigens, is less well
Externí odkaz:
https://doaj.org/article/817f14afd14f4171ab4d81ffe9b0d460
Autor:
Lisa M. Graf, Sina C. Rosenkranz, Angelique Hölzemer, Christian Hagel, Einar Goebell, Sabine Jordan, Manuel A. Friese, Marylyn M. Addo, Julian Schulze zur Wiesch, Claudia Beisel
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background: Progressive multifocal leukoencephalopathy (PML) caused by JCV is a rare but frequently fatal disease of the central nervous system, usually affecting immunocompromised individuals. Our study aims to expand the data on patient characteris
Externí odkaz:
https://doaj.org/article/e8ee11f37e3d4d42affb9bbe429c43d2
Autor:
Anaïs Chapel, Wilfredo F. Garcia-Beltran, Angelique Hölzemer, Maja Ziegler, Sebastian Lunemann, Gloria Martrus, Marcus Altfeld
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The activating NK cell receptor KIR2DS1 has been shown to be involved in many disorders including autoimmune diseases, malignancies and pregnancy outcomes. However, the precise ligands and functions of this receptor remain unclear. We aimed
Externí odkaz:
https://doaj.org/article/3a5085e41caa41e8b81a476f571ddaf4
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Natural killer (NK) cells are effector lymphocytes of the innate immune system that are able to mount a multifaceted antiviral response within hours following infection. This is achieved through an array of cell surface receptors surveilling host cel
Externí odkaz:
https://doaj.org/article/a0fcd3e322e24dcdbf73a333db58d75d
Autor:
Angelique Hölzemer, Christina F Thobakgale, Camilo A Jimenez Cruz, Wilfredo F Garcia-Beltran, Jonathan M Carlson, Nienke H van Teijlingen, Jaclyn K Mann, Manjeetha Jaggernath, Seung-gu Kang, Christian Körner, Amy W Chung, Jamie L Schafer, David T Evans, Galit Alter, Bruce D Walker, Philip J Goulder, Mary Carrington, Pia Hartmann, Thomas Pertel, Ruhong Zhou, Thumbi Ndung'u, Marcus Altfeld
Publikováno v:
PLoS Medicine, Vol 12, Iss 11, p e1001900; discussion e1001900 (2015)
BackgroundViruses can evade immune surveillance, but the underlying mechanisms are insufficiently understood. Here, we sought to understand the mechanisms by which natural killer (NK) cells recognize HIV-1-infected cells and how this virus can evade
Externí odkaz:
https://doaj.org/article/fa6dc56a9531426d9574a273ad87bc21
Autor:
Jan P. Bremer, Martin E. Baumdick, Marius S. Knorr, Lucy H.M. Wegner, Jasmin Wesche, Ana Jordan-Paiz, Johannes M. Jung, Andrew J. Highton, Julia Jäger, Ole Hinrichs, Sebastien Brias, Jennifer Niersch, Luisa Müller, Renée R.C.E. Schreurs, Tobias Koyro, Sebastian Löbl, Leonore Mensching, Leonie Konczalla, Annika Niehrs, Florian W. R. Vondran, Christoph Schramm, Angelique Hölzemer, Karl Oldhafer, Ingo Königs, Stefan Kluge, Daniel Perez, Konrad Reinshagen, Steven T. Pals, Nicola Gagliani, Sander P. Joosten, Maya Topf, Marcus Altfeld, Madeleine J. Bunders
Organoids have emerged as a powerful technology to investigate human development, model diseases and for drug discovery. However, analysis tools to rapidly and reproducibly quantify organoid parameters from microscopy images are lacking. We developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13521250821e90d01118ad2f34ec3450
https://doi.org/10.1101/2022.09.06.506648
https://doi.org/10.1101/2022.09.06.506648
Autor:
Kristina Russu, Christian Körner, Mirjam E Belderbos, Kimberly J. Möller, Suze A. Jansen, Mareike Ohms, Annika Niehrs, Ingo Königs, Anja Ehrhardt, Johannes M. Jung, Lucy Wegner, Martin E. Baumdick, Helga Hofmann-Sieber, Thomas Dobner, Marc Lütgehetmann, Madeleine J. Bunders, Wilhelm Ching, Marcus Altfeld, Angelique Hölzemer, Kevin Duisters, Caroline A. Lindemans, Sven Peine, Tobias Koyro, Wenli Zhang, Daniel Perez, Jens B. Bosse, Eric Spierings, Konrad Reinshagen
Publikováno v:
Science immunology. 6(63)
Human adenoviruses (HAdVs) are a major cause for disease in children, in particular after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Currently, effective therapies for HAdV infections in immunocompromised hosts are lacking. To de
Autor:
Anne Lautenbach, Jörg Schrader, Angelique Hölzemer, Ansgar W. Lohse, Berit C. Behrends, Hans O. Pinnschmidt, Thomas Renné, T Fründt, Jocelyn de Heer, Niko Schröder
Publikováno v:
Zeitschrift fur Gastroenterologie. 60(9)
Diabetes mellitus is a major risk factor for microvascular disease, leading to chronic kidney injury or cardiovascular disease, but there is a tremendous proportion of patients worldwide who suffer from undiagnosed diabetes. Until now, little is know
Autor:
Sebastian Lunemann, Emma Kraus, Tobias B. Huber, Tobias Koyro, Florian Henseling, Adam Grundhoff, Christian Körner, Pia Fittje, Thorsten Wiech, Johannes Jung, Nicole Fischer, Sonia Wulf, Ulf Panzer, Marcus Altfeld, Angelique Hölzemer
Publikováno v:
Kidney international. 99(5)
BK polyomavirus-associated nephropathy is a common complication after kidney transplantation leading to reduced graft function or loss. The molecular pathogenesis of BK polyomavirus-induced nephropathy is not well understood. A recent study had descr
Autor:
Christina M. Stürzel, Gloria Martrus, Janet I. Akko, Wilfredo F. Garcia-Beltran, Hui Li, Beatrice H. Hahn, Daniel Sauter, Laura Richert, Angelique Hölzemer, Thomas van Stigt Thans, Christina Ochsenbauer, John C. Kappes, Christopher T. Ford, Frank Kirchhoff, Marcus Altfeld, Annika Niehrs
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2019, 93 (20), ⟨10.1128/JVI.00719-19⟩
Journal of Virology, 2019, 93 (20), ⟨10.1128/JVI.00719-19⟩
Journal of Virology, American Society for Microbiology, 2019, 93 (20), ⟨10.1128/JVI.00719-19⟩
Journal of Virology, 2019, 93 (20), ⟨10.1128/JVI.00719-19⟩
International audience; Human immunodeficiency virus type 1 (HIV-1) has evolved elaborate ways to evade immune cell recognition, including downregulation of classical HLA class I (HLA-I) from the surfaces of infected cells. Recent evidence identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749c7019dff570ff409413aca5425bf1
https://hal.inria.fr/hal-02426899
https://hal.inria.fr/hal-02426899