Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Angeline de Bruyns"'
Autor:
Benjamin Geiling, Guillaume Vandal, Ada R Posner, Angeline de Bruyns, Kendall L Dutchak, Samantha Garnett, David Dankort
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76279 (2013)
The ability to express exogenous cDNAs while suppressing endogenous genes via RNAi represents an extremely powerful research tool with the most efficient non-transient approach being accomplished through stable viral vector integration. Unfortunately
Externí odkaz:
https://doaj.org/article/c3cd8bad02c94324b1d5f5052baecb9b
Autor:
David Dankort, Ran Shu, Kendall Dutchak, Veronique Provencher-Tom, Angeline de Bruyns, Sam Garnett
Figure S1. Creation of Inducible-BRAF-Inducible Senescent Cells. Figure S2. Summary of lentiviral based shRNA screen for OIS targets. Figure S3. Knockdown of IAPP expression by shRNA. Figure S4. Perturbation of IAPP and ERK2. Figure S5. Loss of IAPP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9279aec7b064c73e552a234726291e45
https://doi.org/10.1158/1541-7786.22526931
https://doi.org/10.1158/1541-7786.22526931
Oncogenic activation of the RTK–RAS–RAF–MEK–ERK pathway occurs in approximately 25% of all human cancers, yet activated RAS, BRAF, or MEK expression in primary cells leads to a prolonged and predominantly irreversible cell-cycle arrest termed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52339d8e8b749ccb4b15a9ff8594702
https://doi.org/10.1158/1541-7786.c.6545418.v1
https://doi.org/10.1158/1541-7786.c.6545418.v1
Supplementary Figure from MOB3A Bypasses BRAF and RAS Oncogene-Induced Senescence by Engaging the Hippo Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed2a7447bd77eedd85464cb64bf6777
https://doi.org/10.1158/1541-7786.22527408.v1
https://doi.org/10.1158/1541-7786.22527408.v1
Publikováno v:
Molecular Cancer Research. 20:770-781
Oncogenic activation of the RTK–RAS–RAF–MEK–ERK pathway occurs in approximately 25% of all human cancers, yet activated RAS, BRAF, or MEK expression in primary cells leads to a prolonged and predominantly irreversible cell-cycle arrest termed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13784558913d3d3651df793d7c6ff0d
https://doi.org/10.1158/1541-7786.mcr-21-0767
https://doi.org/10.1158/1541-7786.mcr-21-0767
Autor:
Sam Garnett, Angeline de Bruyns, David Dankort, Kendall L. Dutchak, Veronique Provencher-Tom, Ran Shu
Publikováno v:
Molecular Cancer Research. 19:874-885
Cellular senescence is characterized by a prolonged and predominantly irreversible cell-cycle arrest state, which is linked to loss of tissue function and aging in mammals. Moreover, in response to aberrant oncogenic signals such as those from oncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5b022f7c86a6c8efa85cd9b165174b
https://doi.org/10.1158/1541-7786.mcr-20-0879
https://doi.org/10.1158/1541-7786.mcr-20-0879
Autor:
Angeline de bruyns, Steven Yip, Pauline T. Truong, Tiffany Patterson, Phil Pollock, Christine Simmons, Jason Hart, Xiaolan Feng, Jocelyn Chai, Chantell Cleversey, Haocheng Li, Cheng-Han Lee, Caroline L. Holloway
Publikováno v:
Journal of gastrointestinal cancer. 53(3)
To examine oncologists’ practice pattern of ordering MA in localized and metastatic GISTs in British Columbia (BC). Patients diagnosed with GIST from January 2008 to December 2017 in BC were identified. Chart review was performed to determine clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8a68ebdd619c267dc5852cc4ad8df2
https://pubmed.ncbi.nlm.nih.gov/34486087
https://pubmed.ncbi.nlm.nih.gov/34486087
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1448
Elucidating gene function is heavily reliant on the ability to modulate gene expression in biological model systems. Although transient expression systems can provide useful information about the biological outcome resulting from short-term gene over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a74027178c471d9f076718f34ecf94a
https://pubmed.ncbi.nlm.nih.gov/27317169
https://pubmed.ncbi.nlm.nih.gov/27317169
Publikováno v:
Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools ISBN: 9781493937516
Elucidating gene function is heavily reliant on the ability to modulate gene expression in biological model systems. Although transient expression systems can provide useful information about the biological outcome resulting from short-term gene over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092a392228cdb5836aa3f5b04bb8e5c8
https://doi.org/10.1007/978-1-4939-3753-0_1
https://doi.org/10.1007/978-1-4939-3753-0_1