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pro vyhledávání: '"Angeline Puranen"'
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells
Autor:
Ian J. Huggins, Tomas Bos, Olivia Gaylord, Christina Jessen, Brianna Lonquich, Angeline Puranen, Jenna Richter, Charlotte Rossdam, David Brafman, Terry Gaasterland, Karl Willert
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
WNT/β-catenin signaling is an essential regulator of many developmental processes. Here, the authors provide evidence that activation of the WNT in human pluripotent stem cells leads to expression WNT target gene SP5, which then acts to diminish exp
Externí odkaz:
https://doaj.org/article/7264afb5c1c3408ea9b76760065ca559
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells
Autor:
Karl Willert, Tomas Bos, Christina Jessen, Ian J. Huggins, Angeline Puranen, Brianna Lonquich, David A. Brafman, Terry Gaasterland, Charlotte Rossdam, Jenna Richter, Olivia Gaylord
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature communications, vol 8, iss 1
The WNT/β-catenin signaling pathway is a prominent player in many developmental processes, including gastrulation, anterior–posterior axis specification, organ and tissue development, and homeostasis. Here, we use human pluripotent stem cells (hPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679314a79da915c20548407d5bb5fed6
http://europepmc.org/articles/PMC5647328
http://europepmc.org/articles/PMC5647328