Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Angelina Vince"'
Autor:
Swarna L. Vijayaraj, Rebecca Feltham, Maryam Rashidi, Daniel Frank, Zhengyang Liu, Daniel S. Simpson, Gregor Ebert, Angelina Vince, Marco J. Herold, Andrew Kueh, Jaclyn S. Pearson, Laura F. Dagley, James M. Murphy, Andrew I. Webb, Kate E. Lawlor, James E. Vince
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Hyperactivation of inflammasome-induced IL-1β can cause immunopathology and is a feature of autoinflammatory diseases. Here, the authors show how ubiquitination of IL-1β limits its activity by targeting it for proteasomal degradation and preventing
Externí odkaz:
https://doaj.org/article/15cc2871bf48403c8f2afd5582cbe869
