Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Angelina Romanova"'
Publikováno v:
Bulletin of the Saint Petersburg State Institute of Technology (Technical University). 55:58-61
The article presents the development of conditions for cell experiments using the Operetta CLS™ imaging system. The significance of high-content analysis parameters is substantiated. The optimal concentration and time parameters for the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4805a0d552d912c19c87ddbeb0ba06
https://doi.org/10.36807/1998-9849-2020-55-81-58-61
https://doi.org/10.36807/1998-9849-2020-55-81-58-61
Autor:
Daria S. Novikova, Viacheslav G. Tribulovich, Aleksandra Sagaidak, Aleksander Garabadzhiu, Angelina Romanova, Tatyana A. Grigoreva
Publikováno v:
Chemico-biological interactions. 344
The problem of chemoresistance development is an inescapable flipside of modern oncotherapy, in particular for сolorectal cancer patients. The search for or development of drugs effective against resistant tumors involves the use of model resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4030fb1c3dc2127d155b48680a9734c
https://pubmed.ncbi.nlm.nih.gov/33974899
https://pubmed.ncbi.nlm.nih.gov/33974899
Autor:
Angelina Romanova, Vyacheslav G. Tribulovich, Svetlana V. Vorona, Aleksandra Sagaidak, Daria S. Novikova, Tatyana A. Grigoreva
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(18)
Chemoresistance is thought to be the cause of low treatment efficacy and mortality in more than 90% of patients with advanced cancer. The activation of drug efflux by P-glycoprotein is the key mechanism of resistance. All known P-gp inhibitors are us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c36c9349eec4d7ff6274074628a068
https://pubmed.ncbi.nlm.nih.gov/32738747
https://pubmed.ncbi.nlm.nih.gov/32738747
Publikováno v:
E3S Web of Conferences, Vol 215, p 05005 (2020)
Reduced delivery of the drug into the cell due to increased activity of specific transporter P-glycoprotein is one of the main mechanisms of drug resistance development. The inhibition of the activity of such a pump increases the intracellular concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de87ae9e2d0976a65461c10eac442360
https://doi.org/10.1051/e3sconf/202021505005
https://doi.org/10.1051/e3sconf/202021505005