The role of dendrin in IgA nephropathy

Autor: Anna Levin, Angelina Schwarz, Jenny Hulkko, Liqun He, Ying Sun, Peter Barany, Annette Bruchfeld, Maria Herthelius, Lars Wennberg, Kerstin Ebefors, Jaakko Patrakka, Christer Betsholtz, Jenny Nyström, Johan Mölne, Kjell Hultenby, Anna Witasp, Annika Wernerson

Background Immunoglobulin A nephropathy (IgAN) and its systemic variant IgA vasculitis (IgAV) damage the glomeruli, resulting in proteinuria, hematuria and kidney impairment. Dendrin is a podocyte-specific protein suggested to be involved in the path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc11423e694a25efb61874a6d890649
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502256

Angiotensin‐converting enzyme 2 and transmembrane protease serine 2 in female and male patients with end‐stage kidney disease

Autor: Samsul, Arefin, Leah, Hernandez, Ward, Liam J., Angelina, Schwarz, GOING-FWD, Collaborators, Peter, Barany, Peter, Stenvinkel, Raparelli, Valeria

Publikováno v: European Journal of Clinical Investigation. 52

Individuals with chronic kidney disease are affected by acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to multiple comorbidities and altered immune system. The first step of the infection process is the binding of SARS-CoV-2 with angiotens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ebfd2380c7e78378070f68e1a8ebd5
https://doi.org/10.1111/eci.13786

Contributors

Autor: Elena Aikawa, S.G. Anderson, Livia Silva Araújo Passos, Samsul Arefin, Per M. Arvidsson, Alberto Avolio, Martin Bachler, Magnus Bäck, Michael J. Bashline, Dakota Becker-Greene, Jamie Bellinge, Amar Bennasroune, Sébastien Blaise, Barry A. Borlaug, Pierre Boutouyrie, Y. Breet, Jerome W. Breslin, Matthew J. Budoff, Mark Butlin, Marina Cecelja, Chen-Huan Chen, Hao-Min Cheng, Yi-Bang Cheng, Julio A. Chirinos, Phil Chowienczyk, Shao-Yuan Chuang, Marie-Annick Clavel, Jordana B. Cohen, Alexis M. Corcoran, William K. Cornwell, Vicente F. Corrales–Medina, Nancy Côté, Thais Coutinho, James Cox, J.K. Cruickshank, Lu Dai, Stella S. Daskalopoulou, Kevin P. Davy, Marc L. De Buyzere, Paul B. Dieffenbach, Laurent Duca, Girish Dwivedi, David G. Edwards, William B. Farquhar, Bo Fernhall, John S. Floras, Laura E. Fredenburgh, Masafumi Fukumitsu, L. Gafane-Matemane, Nestor Gahungu, Ahmed K. Ghanem, Thierry C. Gillebert, Philippe Gillery, Delphine Gomez, Ezequiel Guzzetti, Bernhard Hametner, Junichiro Hashimoto, Kevin S. Heffernan, Brooks A. Hibner, Sam Hobson, Nien-Wen Hu, T.M. Hughes, Jay D. Humphrey, Stéphane Jaisson, Nadjia Kachenoura, Kazuomi Kario, Prasad V.G. Katakam, Goro Katsuumi, Avinash Kondiboyina, Sándor J. Kovács, R. Kruger, Karolina Kublickiene, Patrick Lacolley, Muriel Laffargue, Arinola O. Lampejo, Agne Laucyte-Cibulskiene, Stéphane Laurent, Hae-Young Lee, Wesley K. Lefferts, Elizabeth C. Lefferts, Adelino F. Leite-Moreira, Chee H. Liew, Joao A.C. Lima, André P. Lourenço, Kaisa Maki-Petaja, Marcy Maracle, Laurent Martiny, Pascal Maurice, Christopher C. Mayer, Barry J. McDonnell, John W. McEvoy, M.L. Meyer, Jean-Baptiste Michel, Philip J. Millar, Tohru Minamino, Gary F. Mitchell, Walter L. Murfee, Jonathan P. Mynard, Massimo Nardone, Peter M. Nilsson, Kevin O'Gallagher, Yoshiaki Ohyama, Kazunori Omote, Jeong Bae Park, Shayn M. Peirce, Philippe Pibarot, Gary L. Pierce, Stuart B. Prenner, Athanase Protogerou, Reed E. Pyeritz, Michael A. Quail, Yogesh N.V. Reddy, Alban Redheuil, Véronique Regnault, Rakhshinda Rehman, Ernst R. Rietzschel, Béatrice Romier-Crouzet, Jasjit Rooprai, Lucia Salvi, Paolo Salvi, Hervé Sartelet, Christian E.H. Schmelzer, A.E. Schutte, Angelina Schwarz, Patrick Segers, James E. Sharman, Ippei Shimizu, Marc A. Simon, Piera Sosa, Bart Spronck, Peter Stenvinkel, Eric J. Stöhr, M. Strauss-Kruger, Ariana Suarez-Martinez, Masayoshi Suda, Shih-Hsien Sung, Isabella Tan, Dimitrios Terentes-Printzios, Raymond R. Townsend, Andrew H. Tran, Elaine M. Urbina, Bharath Ambale Venkatesh, Charalambos Vlachopoulos, Anton Vonk Noordegraaf, Amandine Wahart, Ji-Guang Wang, Siegfried Wassertheurer, Andrew James Webb, Thomas Weber, Berend E. Westerhof, Ian B. Wilkinson, Yohko Yoshida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48d3adc7158dec18dc3b303db65c95d3
https://doi.org/10.1016/b978-0-323-91391-1.01002-5

Coro2b, a podocyte protein downregulated in human diabetic nephropathy, is involved in the development of protamine sulphate-induced foot process effacement

Autor: Jaakko Patrakka, David Unnersjö Jess, Katja Möller-Hackbarth, Angelina Schwarz, Lwaki Ebarasi, Sonia Zambrano, Annika Wernerson, Mark Lal, Hans Blom

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports

Podocytes have an important role in the pathogenesis of diabetic nephropathy (DN). Podocyte foot process effacement, mediated largely by the actin-based cytoskeleton of foot processes, is commonly detected in DN and is believed to be a key pathogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddc8aa840554a392aa8629249700a5c
https://doi.org/10.1038/s41598-019-45303-y

FYVE domain-containing protein ZFYVE28 regulates EGFR-signaling in podocytes but is not critical for the function of filtration barrier in mice

Autor: Patricia Q. Rodriguez, Katja Möller-Hackbarth, Jing Guo, Angelina Schwarz, Jaakko Patrakka, Sonia Zambrano

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

The kidney ultrafiltration barrier is formed of endothelial cells, the glomerular basement membrane and podocytes. Podocytes have a central role in normal physiology and disease pathogenesis of the glomerulus. Signaling through epidermal growth facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6314d3f890f1b3f1bb8478baf1fe5b0
https://pubmed.ncbi.nlm.nih.gov/29549365