Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Angeliki, Zaniou"'
Autor:
Andrew Tsotinis, Stavroula Georgakopoulou, Stefanos Riganas, Jean-François Mirjolet, Maria Theodoropoulou, Margarita Prassa, Vassilios I. Moutsos, Andreas Eleutheriades, Guillaume Serin, Alexandre Vamvakides, Humaira Khan, Angeliki Zaniou, Athanasios Mantelas, Ioannis Papanastasiou, George B. Foscolos, Kostas Dimas, Stavroula Pondiki, Vassilios N. Kourafalos
Publikováno v:
Journal of Medicinal Chemistry. 55:10241-10261
The synthesis of the adamantane phenylalkylamines 2a-d, 3a-c, and 4a-e is described. These compounds exhibited significant antiproliferative activity, in vitro, against eight cancer cell lines tested. The σ(1), σ(2), and sodium channel binding affi
Autor:
Andrew Tsotinis, Margarita Prassa, Guillaume Serin, Ioannis Papanastasiou, Humaira Khan, Stavroula Georgakopoulou, Vassilios I. Moutsos, Jean-Jacques Bourguignon, Jean-François Mirjolet, Vassilios N. Kourafalos, Angeliki Zaniou, Alexandre Vamvakides, Stavroula Pondiki, Stefanos Riganas, Andreas Eleutheriades, George B. Foscolos, Kostas Dimas, Maria Theodoropoulou
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:3323-3331
The synthesis of N-{4-[a-(1-adamantyl)benzyl]phenyl}piperazines 2a-e is described. The in vitro antiproliferative activity of most compounds against main cancer cell lines is significant. The σ(1), σ(2)-receptors and sodium channels binding affinit
Autor:
Stefanos, Riganas, Ioannis, Papanastasiou, George B, Foscolos, Andrew, Tsotinis, Jean-Jacques, Bourguignon, Guillaume, Serin, Jean-François, Mirjolet, Kostas, Dimas, Vassilios N, Kourafalos, Andreas, Eleutheriades, Vassilios I, Moutsos, Humaira, Khan, Stavroula, Georgakopoulou, Angeliki, Zaniou, Margarita, Prassa, Maria, Theodoropoulou, Stavroula, Pondiki, Alexandre, Vamvakides
Publikováno v:
Bioorganicmedicinal chemistry. 20(10)
The synthesis of N-{4-[a-(1-adamantyl)benzyl]phenyl}piperazines 2a-e is described. The in vitro antiproliferative activity of most compounds against main cancer cell lines is significant. The σ(1), σ(2)-receptors and sodium channels binding affinit
Autor:
Andreas Eleutheriades, Vassilios N. Kourafalos, Athanasios Mantelas, Ioannis Papanastasiou, Alexandre Vamvakides, Stavroula Pondiki, Stavroula Georgakopoulou, Stefanos Riganas, Vassilios I. Moutsos, Kostas Dimas, George B. Foscolos, Maria Theodoropoulou, Prassa Margarita, Angeliki Zaniou, Andrew Tsotinis, Humaira Khan
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 8(4)
The synthesis of 4-(1-adamantyl)-4,4-diarylbutylamines 1, 5-(1-adamantyl)-5,5-diarylpentylamines 2 and 6-(1-adamantyl)-6,6-diarylhexylamines 3 is described and the σ1, σ2-receptors and sodium channels binding affinity of compounds 1 were investigat
Publikováno v:
Cancer immunology, immunotherapy : CII. 51(5)
The Wilms' tumour 1 (WT1) protein is over-expressed in several types of cancer including leukaemias and might therefore constitute a novel target for immunotherapy. Recently, human leucocyte antigen (HLA) class I-binding WT1 peptides have been identi