Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Angelika Manhart"'
Autor:
Vivienne Leech, Fiona N Kenny, Stefania Marcotti, Tanya J Shaw, Brian M Stramer, Angelika Manhart
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 7, p e1011879 (2024)
Collective alignment of cell populations is a commonly observed phenomena in biology. An important example are aligning fibroblasts in healthy or scar tissue. In this work we derive and simulate a mechanistic agent-based model of the collective behav
Externí odkaz:
https://doaj.org/article/784d7bc91d29417cac8fc2c1611642d8
Publikováno v:
eLife, Vol 12 (2023)
Cells use signal relay to transmit information across tissue scales. However, the production of information carried by signal relay remains poorly characterised. To determine how the coding features of signal relay are generated, we used the classic
Externí odkaz:
https://doaj.org/article/f9719c2f3cf9425b9c2a0366e1b1542f
Publikováno v:
Royal Society Open Science, Vol 9, Iss 12 (2022)
We investigate the collective motion of self-propelled agents in an environment filled with obstacles that are tethered to fixed positions via springs. The active particles are able to modify the environment by moving the obstacles through repulsion
Externí odkaz:
https://doaj.org/article/9851a0a6e0ea489b97207217ef028701
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010548 (2022)
Predictability is a fundamental requirement in biological engineering. As we move to building coordinated multicellular systems, the potential for such systems to display chaotic behaviour becomes a concern. Therefore understanding which systems show
Externí odkaz:
https://doaj.org/article/72ee517f9eb94601a1fe8115e86d6f6d
Autor:
Niv Ierushalmi, Maya Malik-Garbi, Angelika Manhart, Enas Abu Shah, Bruce L Goode, Alex Mogilner, Kinneret Keren
Publikováno v:
eLife, Vol 9 (2020)
Centering and decentering of cellular components is essential for internal organization of cells and their ability to perform basic cellular functions such as division and motility. How cells achieve proper localization of their organelles is still n
Externí odkaz:
https://doaj.org/article/fe062294b29646aa939cb012c89993c5
Autor:
Angelika Manhart, Téa Aleksandra Icheva, Christophe Guerin, Tobbias Klar, Rajaa Boujemaa-Paterski, Manuel Thery, Laurent Blanchoin, Alex Mogilner
Publikováno v:
eLife, Vol 8 (2019)
Principles of regulation of actin network dimensions are fundamentally important for cell functions, yet remain unclear. Using both in vitro and in silico approaches, we studied the effect of key parameters, such as actin density, ADF/Cofilin concent
Externí odkaz:
https://doaj.org/article/fab7c2ddcb384449b9c3f74d95f6b64d
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 6, p e1006208 (2018)
Many types of large cells have multiple nuclei. In skeletal muscle fibers, the nuclei are distributed along the cell to maximize their internuclear distances. This myonuclear positioning is crucial for cell function. Although microtubules, microtubul
Externí odkaz:
https://doaj.org/article/184d8d3f57ef47919d71d1f48932946a
Publikováno v:
ACS macro letters. 7(6)
Linear polyethylenimine (L-PEI) has been the gold standard for gene delivery and is typically prepared by hydrolysis from poly(2-oxazoline)s. Recently, also the anionic polymerization of activated aziridines was reported as a potential pathway toward
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d54eb6bd4fa56c7d89421fd7aaf4dbe
https://pubmed.ncbi.nlm.nih.gov/35632962
https://pubmed.ncbi.nlm.nih.gov/35632962
Cells use signal relay to transmit information across tissue scales. However, the production of information carried by signal relay remains poorly characterised. To determine how the coding features of signal relay are generated, we used the classic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e7261505650217c0b14e1be327028e
https://doi.org/10.1101/2022.01.07.475371
https://doi.org/10.1101/2022.01.07.475371
