Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Angelika M. Vollmar"'
Publikováno v:
Cells, Vol 13, Iss 8, p 696 (2024)
Actin is a protein of central importance to many cellular functions. Its localization and activity are regulated by interactions with a high number of actin-binding proteins. In a yeast two-hybrid (Y2H) screening system, snail family transcriptional
Externí odkaz:
https://doaj.org/article/f87bb17cf2c24f1faead996e2d83e41c
Autor:
Franz Geisslinger, Martin Müller, Yu-Kai Chao, Christian Grimm, Angelika M. Vollmar, Karin Bartel
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-14 (2022)
Abstract Despite novel therapy regimens and extensive research, chemoresistance remains a challenge in leukemia treatment. Of note, recent studies revealed lysosomes as regulators of cell death and chemotherapy response, suggesting this organelle is
Externí odkaz:
https://doaj.org/article/a55e8a39a48d4818944a7025f699aa9d
Autor:
Florian Lengauer, Franz Geisslinger, Antje Gabriel, Karin von Schwarzenberg, Angelika M. Vollmar, Karin Bartel
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
It is widely known that most cancer cells display an increased reliance on glutaminolysis to sustain proliferation and survival. Combining glutamine deprivation with additional anti-cancer therapies is an intensively investigated approach to increase
Externí odkaz:
https://doaj.org/article/c550f5f3982447b595b492730fbb53e5
Autor:
Shuaijun Wang, Maximilian Meixner, Lushuang Yu, Ling Zhuo, Lisa Karmann, Uli Kazmaier, Angelika M. Vollmar, Iris Antes, Stefan Zahler
Publikováno v:
ACS Omega, Vol 6, Iss 34, Pp 22165-22172 (2021)
Externí odkaz:
https://doaj.org/article/1071bdb5fd344309a744b618707f6820
Autor:
Martina Meßner, Melanie M. Mandl, Mathias W. Hackl, Till Reinhardt, Maximilian A. Ardelt, Karolina Szczepanowska, Julian E. Frädrich, Jens Waschke, Irmela Jeremias, Anja Fux, Matthias Stahl, Angelika M. Vollmar, Stephan A. Sieber, Johanna Pachmayr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The human mitochondrial ClpXP protease complex (HsClpXP) has recently attracted major attention as a target for novel anti-cancer therapies. Despite its important role in disease progression, the cellular role of HsClpXP is poorly characteri
Externí odkaz:
https://doaj.org/article/547435541d554b50bc1ec5f3fc98a476
Autor:
Ponsawan Netcharoensirisuk, Carla Abrahamian, Rachel Tang, Cheng-Chang Chen, Anna Scotto Rosato, Wyatt Beyers, Yu-Kai Chao, Antonio Filippini, Santiago Di Pietro, Karin Bartel, Martin Biel, Angelika M. Vollmar, Kaoru Umehara, Wanchai De-Eknamkul, Christian Grimm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Two-pore channel 2 (TPC2) resides in endolysosomal membranes but also in lysosome-related organelles such as the melanin producing melanosomes. Gain-of-function polymorphisms in hTPC2 are associated with decreased melanin production and blon
Externí odkaz:
https://doaj.org/article/8f4de751c6ed48b481f4c92a2999702f
Autor:
Karin Bartel, Helmut Pein, Bastian Popper, Sabine Schmitt, Sudha Janaki-Raman, Almut Schulze, Florian Lengauer, Andreas Koeberle, Oliver Werz, Hans Zischka, Rolf Müller, Angelika M. Vollmar, Karin von Schwarzenberg
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background The understanding of lysosomes has been expanded in recent research way beyond their view as cellular trash can. Lysosomes are pivotal in regulating metabolism, endocytosis and autophagy and are implicated in cancer. Recently it w
Externí odkaz:
https://doaj.org/article/44f0d07f9d1342d094461524911b0514
Autor:
Carolin M.-L. Gleissner, Carolin L. Pyka, Wolfgang Heydenreuter, Thomas F. Gronauer, Carina Atzberger, Vadim S. Korotkov, Weiting Cheng, Stephan M. Hacker, Angelika M. Vollmar, Simone Braig, Stephan A. Sieber
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
Externí odkaz:
https://doaj.org/article/8a702a398cd544bc9174ef6ea10e4433
Autor:
Bernhard Illes, Adrian Fuchs, Florian Gegenfurtner, Evelyn Ploetz, Stefan Zahler, Angelika M. Vollmar, Hanna Engelke
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102185- (2021)
Summary: The mechanical properties of the extracellular matrix strongly influence tumor progression and invasion. Yes-associated protein (YAP) has been shown to be a key regulator of this process translating mechanical cues from the extracellular mat
Externí odkaz:
https://doaj.org/article/a348249f021846f3807a55bac457682f
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108015- (2020)
Summary: Endothelial tube formation on a reconstituted basement membrane (Matrigel) is a well-established in vitro model for studying the processes of angiogenesis and vasculogenesis. However, to date, the organizing principles that underlie the morp
Externí odkaz:
https://doaj.org/article/59eaf2c2bc6440a49452b3651053465f