Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Angelika Lásiková"'
Publikováno v:
Marine Drugs, Vol 21, Iss 1, p 19 (2022)
Marine microorganisms are an important source of natural polyketides, which have become a significant reservoir of lead structures for drug design due to their diverse biological activities. In this review, we provide a summary of the resources, stru
Externí odkaz:
https://doaj.org/article/09aa6999a876406c8fbb87e00ddbb363
Autor:
Angelika Lásiková, Jana Doháňošová, Mária Štiblariková, Martin Parák, Ján Moncol, Tibor Gracza
Publikováno v:
Molecules, Vol 24, Iss 5, p 862 (2019)
The paper describes the first total synthesis of natural varioxiranol A by chiral pool approach and confirmation of its absolute configuration by single-crystal X-ray analysis. The target varioxiranol A and its 4-epimer were obtained after 10 steps f
Externí odkaz:
https://doaj.org/article/a1c9c683a20845e087b3893156cf4556
Publikováno v:
ARKIVOC, Vol 2012, Iss 6, Pp 365-383 (2012)
Externí odkaz:
https://doaj.org/article/e31aad7da7584b4aa0e2f98fa13ee006
Publikováno v:
ARKIVOC, Vol 2004, Iss 7, Pp 292-302 (2004)
Externí odkaz:
https://doaj.org/article/f69dd1cea1014772b829b71c574b5a84
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 9, Pp o2381-o2381 (2010)
The constitution and relative configuration at the stereogenic centres and stereochemistry of the C—C double bond formed during PdII-catalysed domino reaction was established by X-ray analysis of the title compound, C10H14O4. The asymmetric unit co
Externí odkaz:
https://doaj.org/article/78de276c0c5e4966a824982bed8092db
Autor:
Mária Štiblariková, Ján Moncol, Jana Doháňošová, Angelika Lásiková, Tibor Gracza, Martin Parák
Publikováno v:
Molecules, Vol 24, Iss 5, p 862 (2019)
Molecules
Volume 24
Issue 5
Molecules
Volume 24
Issue 5
The paper describes the first total synthesis of natural varioxiranol A by chiral pool approach and confirmation of its absolute configuration by single-crystal X-ray analysis. The target varioxiranol A and its 4-epimer were obtained after 10 steps f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f3e3f0975c8464323319ea20e172e3
http://www.mdpi.com/1420-3049/24/5/862
http://www.mdpi.com/1420-3049/24/5/862
Publikováno v:
Acta Chimica Slovaca. 5:220-224
A modification of biphenylyltetrazole moiety of Losartan (A) by 3-(2-heteroaryl)-pyrazolotetrazole (B) is described. Ketone semicarbazones react with two moles of phosphorus oxychloride-dimethylformamide with the formation of 3-substituted pyrazol-4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b5e0a4e76af520b41cde2e2eb34b24
https://doi.org/10.2478/v10188-012-0033-z
https://doi.org/10.2478/v10188-012-0033-z
Autor:
Angelika Lásiková, Martial Toffano, Tibor Gracza, Jozef Kožíšek, Lucia Hlavinova, Jana Doháňošová, Giang Vo-Thanh
Publikováno v:
Tetrahedron: Asymmetry. 23:818-827
The Pd-catalyzed cyclization and cross-coupling of hydroxylated alkenes in domino reactions are described. The alkenols undergo Pd-catalyzed cyclization and subsequent cross-coupling reactions with aryl bromides to afford (poly)hydroxylated tetrahydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da382cdd769c1a81e87fdfdf9d98d201
https://doi.org/10.1016/j.tetasy.2012.05.020
https://doi.org/10.1016/j.tetasy.2012.05.020
Publikováno v:
ARKIVOC, Vol 2012, Iss 6, Pp 365-383 (2012)
Novel analogues of (+)-varitriol have been synthesised via Julia-Kocienski olefination from -Dribonolactone. Newly prepared compounds were screened for their in vitro cytotoxicity towards certain human tumours and NCI60 cancer cell line panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bbd42c997f98ddbed6f0a721498fc1
https://doi.org/10.3998/ark.5550190.0013.633
https://doi.org/10.3998/ark.5550190.0013.633
Publikováno v:
Synthesis. 2010:3449-3452
A short and efficient total synthesis of cytotoxic natural (+)-varitriol has been accomplished in eight steps from γ-D-ribonolactone and 2,3-dimethylanisole in 41% overall yield. The key features include a highly stereoselective introduction of meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9cfa741f625caddb70a0c7ffcbae86e
https://doi.org/10.1055/s-0030-1258201
https://doi.org/10.1055/s-0030-1258201