Výsledky vyhledávání - "Angelika Kritz"

Cell-selective viral gene delivery vectors for the vasculature

Autor: Andrew H, Baker, Angelika, Kritz, Lorraine M, Work, Stuart A, Nicklin

Publikováno v: Experimental physiology. 90(1)

Clinical gene therapy for cardiovascular disease remains achievable. To date, however, preclinical studies and clinical trials have highlighted shortfalls in viral gene delivery to vascular cells. These include poor efficiency, poor target tissue sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a661b184bc4df7a315be89b8bb56636
https://pubmed.ncbi.nlm.nih.gov/15542621

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Targeted gene delivery to human airway epithelial cells with synthetic vectors incorporating novel targeting peptides selected by phage display

Autor: Michael A. Pilkington-Miksa, Angelika Kritz, Stephen L. Hart, Alethea B. Tabor, Douglas H. Lester, Barry Marshall, Helen C. Hailes, S. E. Barker, Marianne C. Jacobsen, Nigel Klein, Paul C. Bell, Michele J. Writer

Publikováno v: Journal of drug targeting. 12(4)

Human airway epithelial cell targeting peptides were identified by biopanning on 1HAEo-cells, a well characterised epithelial cell line. Bound phage were recovered after three rounds of binding, high stringency washing and elution, leading to the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a77553bbaa7595283d62538be17f17
https://pubmed.ncbi.nlm.nih.gov/15506167

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