Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Angelika K. Teresky"'
Autor:
Arnold J. Levine, Scott Lowe, Shengkan Jin, Angelika K. Teresky, Elisa de Stanchina, Wenwei Hu, Zhaohui Feng
Supplementary Figure 1 from The Regulation of AMPK β1, TSC2, and PTEN Expression by p53: Stress, Cell and Tissue Specificity, and the Role of These Gene Products in Modulating the IGF-1-AKT-mTOR Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0716623f3bf7f0a5d6c0db10024a45
https://doi.org/10.1158/0008-5472.22370922
https://doi.org/10.1158/0008-5472.22370922
Autor:
Arnold J. Levine, Eva Hernando, Angelika K. Teresky, Wenwei Hu, Zhaohui Feng, Carlos Cordon-Cardo
Publikováno v:
Proceedings of the National Academy of Sciences. 104:16633-16638
Cancer is a disease of aging. The accumulation of mutations in individual cells over a lifetime is thought to be the reason. In this work, we explored an additional hypothesis: could p53 function decline with age, which would contribute to an enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96515af5d6413a663ccad039b9bcd804
https://doi.org/10.1073/pnas.0708043104
https://doi.org/10.1073/pnas.0708043104
Publikováno v:
Immunogenetics. 49:949-956
Cytotoxic T lymphocytes play a predominant role in allograft rejection. They mediate this process through recognition of foreign major histocompatibility complex (MHC) class I surface molecules encoded at the H2 locus. Embryonal carcinoma cells, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e28edcf0a293e7b4b3b3c5984ea7c57
https://doi.org/10.1007/s002510050578
https://doi.org/10.1007/s002510050578
Autor:
Gerard P. Zambetti, Arnold J. Levine, Angelika K. Teresky, Dirk P. Dittmer, Shelley Chu, Sibani Pati, Cathy A. Finlay, M Moore
Publikováno v:
Europe PubMed Central
We report that the expression of murine or human mutant p53 proteins in cells with no endogenous p53 proteins confers new or additional phenotypes upon these cells. Mutant p53 proteins expressed in cell lines lacking p53 resulted in either enhanced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcaf97a6f9845f59cd3ca5f5165b8ae
https://doi.org/10.1038/ng0593-42
https://doi.org/10.1038/ng0593-42
Publikováno v:
Journal of Virology. 66:641-649
Many diverse tumors contain cells that select for mutations at the p53 gene locus. This appears to be the case because the p53 gene product can act as a negative regulator of cell division or a tumor suppressor. These mutations then eliminate this ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7676a68b9c6399b94da067c5cd054bb9
https://doi.org/10.1128/jvi.66.2.641-649.1992
https://doi.org/10.1128/jvi.66.2.641-649.1992
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc915b07d65df61f77df367f5cdf958c
https://doi.org/10.1038/nprot.2007.507
https://doi.org/10.1038/nprot.2007.507
Publikováno v:
Nature. 450(7170)
The transcription factor p53 has been studied extensively as a tumour suppressor, but little is known about its normal physiological role. A study in mice now links normal p53 function to reproduction and fertility. A p53 deficiency results in poor i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3bacbe9b1f8f478b6bd62d1c27dd85
https://pubmed.ncbi.nlm.nih.gov/18046386
https://pubmed.ncbi.nlm.nih.gov/18046386
Autor:
Arnold J. Levine, Elisa de Stanchina, Shengkan Jin, Scott W. Lowe, Wenwei Hu, Zhaohui Feng, Angelika K. Teresky
Publikováno v:
Cancer research. 67(7)
The insulin-like growth factor 1 (IGF-1)-AKT-mTOR pathways sense the availability of nutrients and mitogens and respond by signaling for cell growth and division. The p53 pathway senses a variety of stress signals which will reduce the fidelity of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b438f55090076195a14cff862924aee
https://pubmed.ncbi.nlm.nih.gov/17409411
https://pubmed.ncbi.nlm.nih.gov/17409411
Inbred 129 strain mice are predisposed to developing male germ cell tumors (GCTs) of the testes. The inherent genetic defects that underlie male GCT susceptibility in the 129 mouse strain are unknown. GCT incidence is increased in 129 strain males th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbcf730dbb05297de5174cd9b379e15
https://europepmc.org/articles/PMC26963/
https://europepmc.org/articles/PMC26963/
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 9(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea013bcce647d125dae878d743fcb47d
https://pubmed.ncbi.nlm.nih.gov/9716666
https://pubmed.ncbi.nlm.nih.gov/9716666