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Autor:
Angelika Horrighs, Annette Schürmann, Claudia Wiza, D. Margriet Ouwens, Daniella Herzfeld de Wiza, Marcel Blumensatt, Emmani B.M. Nascimento, Alexandra Chadt, Hadi Al-Hasani, Timo Kanzleiter, Heidi Mueller
Publikováno v:
Archives of physiology and biochemistry. 120(2)
Silencing proline-rich Akt substrate of 40-kDa (PRAS40) impairs insulin signalling in skeletal muscle.This study assessed the effects of over-expressing wild type or mutant AAA-PRAS40, in which the major phosphorylation sites and mTORC1-binding site