Výsledky vyhledávání - "Angelika Ehrfeld"

Regulation of T cell receptor (TCR)-β locus allelic exclusion and initiation of TCR-α locus rearrangement in immature thymocytes by signaling through the CD3 complex

Autor: Klaus Eichmann, Baoping Wang, Angelika Ehrfeld, Christiann N. Levelt, Cox Terhorst

Publikováno v: European Journal of Immunology. 25:1257-1261

During thymocyte differentiation, the T cell receptor (TCR)-beta genes are rearranged before the TCR-alpha genes. Immature CD4-8- double-negative thymocytes with a productive rearrangement of the TCR-beta locus are selected to continue maturation to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439de6025a62101713ce4313a7f75653
https://doi.org/10.1002/eji.1830250519

Zobrazit plný text záznamu

Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program

Autor: Klaus Eichmann, Christiaan N. Levelt, Angelika Ehrfeld

Publikováno v: The Journal of Experimental Medicine

Several recent observations suggest that successful rearrangement of the T cell receptor (TCR) beta locus induces several important events in thymocyte maturation. Allelic exclusion is achieved by interruption of further rearrangement of the beta loc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8739fd7ea0857ede6b62ae046abb68ab
http://europepmc.org/articles/PMC2190948

Zobrazit plný text záznamu

Cell Interaction Molecules Regulating T Cell Receptor Mediated Signal Transduction: A Comparison of Peripheral T Cell with Developing Thymocytes

Autor: Alexandre J. Potocnik, T. Bartlott, Christiaan N. Levelt, Klaus Eichmann, Angelika Ehrfeld, Kai M. Saizawa, A. Reimann, S. Suzuki, Andreas Würch, A. Zgaga-Griesz

Publikováno v: Progress in Immunology Vol. VIII ISBN: 9783642514814

Signal transduction through the αβ CD3 T cell receptor (TCR) can induce vastly different cellular responses at different stages of T cell differentiation. The earliest form of TCR mediated signalling is seen in immature CD4+8 thymocytes in which li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f66898459f9c1f6657085045675a0fc6
https://doi.org/10.1007/978-3-642-51479-1_35

Zobrazit plný text záznamu

A comparative assessment of the roles of CD8 and CD2 in the functions of activated murine CD8+ T lymphocytes

Autor: Jörg Kupsch, Klaus Eichmann, Angelika Ehrfeld, Astrid Reimann, Bernhard Maier, Kai M. Saizawa, Birgitta Clinchy

Publikováno v: Immunology letters. 30(2)

Both CD8 and CD2 are T cell surface receptors involved in physical cell interaction and in transmembrane signalling. The present paper addresses their role in the induction of two different functions of the cloned murine cytotoxic T cell C196: target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099f61ad091a3ea7e1f4dbd76de5abd9
https://pubmed.ncbi.nlm.nih.gov/1684570

Zobrazit plný text záznamu

Amplification of Oncogenes and Integrated SV40 Sequences in Mammalian Cells by the Decay of Incorporated Iodine-125

Autor: Angelika Ehrfeld, Felicitas Planas-Bohne, Christine Lücke-Huhle, Christine Lucke-Huhle

Publikováno v: Radiation Research. 108:43

Iodine-125, in the form of 5-[125I]iododeoxyuridine (I-UdR), was incorporated into the DNA of SV40 transformed Chinese hamster embryo cells. Disintegration of the 125I led to increased cell killing with increasing dose as measured by the colony-formi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39f90dbe18d3485b1bcd5442d8d9b3d3
https://doi.org/10.2307/3576968

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání