Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Angelika Diehl"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Antibiotics targeting cell wall synthesis display an unexplained gap between in vivo efficacy and in vitro binding affinity for their target. Here, Piepenbreier et al. develop a model for bacterial cell wall biosynthesis, show how it is affected by a
Externí odkaz:
https://doaj.org/article/a814415456d14601a61c11483ea4c660
Publikováno v:
mSystems, Vol 5, Iss 4 (2020)
ABSTRACT Extracytoplasmic function σ factors (ECFs) belong to the most abundant signal transduction mechanisms in bacteria. Among the diverse regulators of ECF activity, class I anti-σ factors are the most important signal transducers in response t
Externí odkaz:
https://doaj.org/article/5108cf67725548ef8e6481ef8d855ce5
Publikováno v:
Antibiotics, Vol 9, Iss 11, p 729 (2020)
Cell wall antibiotics are important tools in our fight against Gram-positive pathogens, but many strains become increasingly resistant against existing drugs. Laspartomycin C is a novel antibiotic that targets undecaprenyl phosphate (UP), a key inter
Externí odkaz:
https://doaj.org/article/28ede80302f84b82a8ef966f77d8a93d
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Cell wall antibiotics are crucial for combatting the emerging wave of resistant bacteria. Yet, our understanding of antibiotic action is limited, as many strains devoid of all resistance determinants display far higher antibiotic tolerance in vivo th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09937b519d9aaab0d58b0805fe558d0b
http://link.springer.com/article/10.1038/s41467-019-10673-4
http://link.springer.com/article/10.1038/s41467-019-10673-4
Publikováno v:
mSystems, Vol 5, Iss 4, p e00310-20 (2020)
mSystems, Vol 5, Iss 4 (2020)
mSystems
mSystems, Vol 5, Iss 4 (2020)
mSystems
In the bacterial world, extracytoplasmic function σ factors (ECFs) are the most widespread family of alternative σ factors, mediating many cellular responses to environmental cues, such as stress. This work uses a computational approach to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46f81156268f0e6fb68f434571587b7
https://doaj.org/article/af64f13418ab4ae7baa52badbbc85d55
https://doaj.org/article/af64f13418ab4ae7baa52badbbc85d55
Extracytoplasmic function σ factors (ECFs) belong to the most abundant signal transduction mechanisms in bacteria. Amongst the diverse regulators of ECF activity, class I anti-σ factors are the most important signal transducers in response to inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f71f1681826e1431df4b427073e75e
