Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Angelika Bongers"'
Autor:
Lin Xiao, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Ali El-Ayoubi, Jezrael L. Revalde, Janith A. Seneviratne, Belamy B. Cheung, Laurence C. Cheung, Rishi S. Kotecha, Andrea Newbold, Stefan Bjelosevic, Greg M. Arndt, Richard B. Lock, Ricky W. Johnstone, Andrei V. Gudkov, Katerina V. Gurova, Michelle Haber, Murray D. Norris, Michelle J. Henderson, Klaartje Somers
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Rearrangements of the Mixed Lineage Leukemia (MLL/KMT2A) gene are present in approximately 10% of acute leukemias and characteristically define disease with poor outcome. Driven by the unmet need to develop better therapies for KMT2A-rearranged leuke
Externí odkaz:
https://doaj.org/article/030ef39db2a746f68cb7bcf2cf823422
Autor:
Mawar Karsa, Emma Ronca, Angelika Bongers, Anna Mariana, Ernest Moles, Timothy W. Failes, Greg M. Arndt, Laurence C. Cheung, Rishi S. Kotecha, Maria Kavallaris, Michelle Haber, Murray D. Norris, Michelle J. Henderson, Lin Xiao, Klaartje Somers
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Patients whose leukemias harbor a rearrangement of the Mixed Lineage Leukemia (MLL/KMT2A) gene have a poor prognosis, especially when the disease strikes in infants. The poor clinical outcome linked to this aggressive disease and the detrimental trea
Externí odkaz:
https://doaj.org/article/a4e7367f914c409982b8e7dce5bbe234
Autor:
Jixuan Gao, MoonSun Jung, Rebekka T. Williams, Danica Hui, Amanda J. Russell, Andrea J. Naim, Alvin Kamili, Molly Clifton, Angelika Bongers, Chelsea Mayoh, Gwo Ho, Clare L. Scott, Wendy Jessup, Michelle Haber, Murray D. Norris, Michelle J. Henderson, on behalf of Australian Ovarian Cancer Study
Publikováno v:
Cancers, Vol 14, Iss 8, p 1878 (2022)
Background: Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy with over 80% of cases already disseminated at diagnosis and facing a dismal five-year survival rate of 35%. EOC cells often spread to the greater omentum where
Externí odkaz:
https://doaj.org/article/309943b0c0a94d9d915568cbc9872776
Autor:
Michelle Haber, Murray D. Norris, Katerina V. Gurova, Andrei V. Gudkov, David S. Ziegler, Anthony J. Cesare, Ricky W. Johnstone, Glenn Marshall, Jamie I. Fletcher, Michelle J. Henderson, Daniel R. Carter, Andrew J. Gifford, Alvin Kamili, Lei Zhai, Sophie Allan, Stephanie Alfred, Georgina Eden, Adam Kearns, Erin Mosmann, Jessica A. Pettitt, Frances K. Kusuma, Jennifer Brand, Hazel Quek, Pooja Venkat, Chelsea Mayoh, Aisling O'Connor, Katerina I. Leonova, Natalia Issaeva, Laura D. Gamble, Anahid Ehteda, Rachael Terry, Angelika Bongers, Emma Ronca, Mawar Karsa, Ruby Pandher, Jayne Murray, Klaartje Somers, Lin Xiao
HT10806TG_CBL0137 treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a65865b88e665572993028e81a66b25
https://doi.org/10.1158/1078-0432.22481328.v1
https://doi.org/10.1158/1078-0432.22481328.v1
Autor:
Michelle Haber, Murray D. Norris, Katerina V. Gurova, Andrei V. Gudkov, David S. Ziegler, Anthony J. Cesare, Ricky W. Johnstone, Glenn Marshall, Jamie I. Fletcher, Michelle J. Henderson, Daniel R. Carter, Andrew J. Gifford, Alvin Kamili, Lei Zhai, Sophie Allan, Stephanie Alfred, Georgina Eden, Adam Kearns, Erin Mosmann, Jessica A. Pettitt, Frances K. Kusuma, Jennifer Brand, Hazel Quek, Pooja Venkat, Chelsea Mayoh, Aisling O'Connor, Katerina I. Leonova, Natalia Issaeva, Laura D. Gamble, Anahid Ehteda, Rachael Terry, Angelika Bongers, Emma Ronca, Mawar Karsa, Ruby Pandher, Jayne Murray, Klaartje Somers, Lin Xiao
Supplementary Figure Legends S1-S16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418baa2ab5037ab880d09c89a3ddcd0f
https://doi.org/10.1158/1078-0432.22481343.v1
https://doi.org/10.1158/1078-0432.22481343.v1
Autor:
Michelle Haber, Murray D. Norris, Katerina V. Gurova, Andrei V. Gudkov, David S. Ziegler, Anthony J. Cesare, Ricky W. Johnstone, Glenn Marshall, Jamie I. Fletcher, Michelle J. Henderson, Daniel R. Carter, Andrew J. Gifford, Alvin Kamili, Lei Zhai, Sophie Allan, Stephanie Alfred, Georgina Eden, Adam Kearns, Erin Mosmann, Jessica A. Pettitt, Frances K. Kusuma, Jennifer Brand, Hazel Quek, Pooja Venkat, Chelsea Mayoh, Aisling O'Connor, Katerina I. Leonova, Natalia Issaeva, Laura D. Gamble, Anahid Ehteda, Rachael Terry, Angelika Bongers, Emma Ronca, Mawar Karsa, Ruby Pandher, Jayne Murray, Klaartje Somers, Lin Xiao
Purpose:We investigated whether targeting chromatin stability through a combination of the curaxin CBL0137 with the histone deacetylase (HDAC) inhibitor, panobinostat, constitutes an effective multimodal treatment for high-risk neuroblastoma.Experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d195a8f4885e0b0f8fe998d3c3ca58
https://doi.org/10.1158/1078-0432.c.6530664.v1
https://doi.org/10.1158/1078-0432.c.6530664.v1
Autor:
Michelle Haber, Murray D. Norris, Katerina V. Gurova, Andrei V. Gudkov, David S. Ziegler, Anthony J. Cesare, Ricky W. Johnstone, Glenn Marshall, Jamie I. Fletcher, Michelle J. Henderson, Daniel R. Carter, Andrew J. Gifford, Alvin Kamili, Lei Zhai, Sophie Allan, Stephanie Alfred, Georgina Eden, Adam Kearns, Erin Mosmann, Jessica A. Pettitt, Frances K. Kusuma, Jennifer Brand, Hazel Quek, Pooja Venkat, Chelsea Mayoh, Aisling O'Connor, Katerina I. Leonova, Natalia Issaeva, Laura D. Gamble, Anahid Ehteda, Rachael Terry, Angelika Bongers, Emma Ronca, Mawar Karsa, Ruby Pandher, Jayne Murray, Klaartje Somers, Lin Xiao
Supplementary Figures S1-S16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792fea8161528a9cd8c896589616c6d0
https://doi.org/10.1158/1078-0432.22481337
https://doi.org/10.1158/1078-0432.22481337
Autor:
Michelle Haber, Murray D. Norris, Katerina V. Gurova, Andrei V. Gudkov, David S. Ziegler, Anthony J. Cesare, Ricky W. Johnstone, Glenn Marshall, Jamie I. Fletcher, Michelle J. Henderson, Daniel R. Carter, Andrew J. Gifford, Alvin Kamili, Lei Zhai, Sophie Allan, Stephanie Alfred, Georgina Eden, Adam Kearns, Erin Mosmann, Jessica A. Pettitt, Frances K. Kusuma, Jennifer Brand, Hazel Quek, Pooja Venkat, Chelsea Mayoh, Aisling O'Connor, Katerina I. Leonova, Natalia Issaeva, Laura D. Gamble, Anahid Ehteda, Rachael Terry, Angelika Bongers, Emma Ronca, Mawar Karsa, Ruby Pandher, Jayne Murray, Klaartje Somers, Lin Xiao
Supplementary Tables S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c658b9df3d28c8753a0e6dc9fa2665
https://doi.org/10.1158/1078-0432.22481334
https://doi.org/10.1158/1078-0432.22481334
Autor:
Laura D. Gamble, Ricky W. Johnstone, Klaartje Somers, Rachael L. Terry, Glenn M. Marshall, Andrei V. Gudkov, Sophie Allan, Georgina L. Eden, Jamie I. Fletcher, Frances K. Kusuma, Stephanie Alfred, Mawar Karsa, Adam Kearns, Michelle J. Henderson, Michelle Haber, Angelika Bongers, Katerina Gurova, Lin Xiao, Anahid Ehteda, Lei Zhai, Erin Mosmann, Katerina I. Leonova, Natalia Issaeva, Pooja Venkat, Aisling O'Connor, Alvin Kamili, David S. Ziegler, Ruby Pandher, Daniel R. Carter, Hazel Quek, Andrew J. Gifford, Jayne Murray, Chelsea Mayoh, Jessica A. Pettitt, Murray D. Norris, Jennifer Brand, Emma Ronca, Anthony J. Cesare
Publikováno v:
Clin Cancer Res
Purpose: We investigated whether targeting chromatin stability through a combination of the curaxin CBL0137 with the histone deacetylase (HDAC) inhibitor, panobinostat, constitutes an effective multimodal treatment for high-risk neuroblastoma. Experi
Autor:
Richard B. Lock, Michelle J. Henderson, Angelika Bongers, Tim Failes, Mawar Karsa, Anna Mariana, Laurence C. Cheung, Andrew J. Gifford, Angelika Kosciolek, Michelle Haber, Ursula R. Kees, Rosemary Sutton, Greg M. Arndt, Murray D. Norris, Klaartje Somers, Rishi S. Kotecha
Publikováno v:
Br J Cancer
BACKGROUND: The prognosis for high-risk childhood acute leukaemias remains dismal and established treatment protocols often cause long-term side effects in survivors. This study aims to identify more effective and safer therapeutics for these patient