Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Angelika Barnekow"'
Autor:
Dieter Waschbüsch, Nicole Hübel, Edith Ossendorf, Evy Lobbestael, Veerle Baekelandt, Andrew J Lindsay, Mary W McCaffrey, Amir R Khan, Angelika Barnekow
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0208889 (2019)
The Rab family of small GTPases regulate various aspects of cellular dynamics in eukaryotic cells. Membrane trafficking has emerged as central to the functions of leucine-rich repeat kinase 2 (LRRK2), which is associated with inherited and sporadic f
Externí odkaz:
https://doaj.org/article/196f08b326604839b85aa77db909dee8
Autor:
Dieter Waschbüsch, Helen Michels, Swantje Strassheim, Edith Ossendorf, Daniel Kessler, Christian Johannes Gloeckner, Angelika Barnekow
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111632 (2014)
Leucine-rich repeat kinase 2 (LRRK2) is a multi-domain 280 kDa protein that is linked to Parkinson's disease (PD). Mutations especially in the GTPase and kinase domains of LRRK2 are the most common causes of heritable PD and are also found in sporadi
Externí odkaz:
https://doaj.org/article/168bc898a2c4443185895c19a2d2a6d3
Autor:
Anika Thyrock, Edith Ossendorf, Martin Stehling, Mark Kail, Tanja Kurtz, Gottfried Pohlentz, Dieter Waschbüsch, Simone Eggert, Etienne Formstecher, Johannes Müthing, Klaus Dreisewerd, Stefan Kins, Bruno Goud, Angelika Barnekow
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64149 (2013)
Small GTPases of the Rab family are important regulators of a large variety of different cellular functions such as membrane organization and vesicle trafficking. They have been shown to play a role in several human diseases. One prominent member, Ra
Externí odkaz:
https://doaj.org/article/c940de76ac58445eaaa25afd8b77130e
Autor:
Namista Islam, Sohinee Bhattacharyya, Bhopal Mohapatra, Matthew D. Storck, Hamid Band, Simarjeet K. Negi, Guoguang Ying, Amarnath Natarajan, Priyanka Arya, Aaqib M. Bhat, Neha Zutshi, Fany Iseka, Sukanya Chakraborty, Timothy A. Bielecki, Pankaj K. Singh, Insha Mushtaq, Eric Tom, Vimla Band, Luke R. Cypher, Haitao Luan, Benjamin T. Goetz, Chittibabu Guda, Angelika Barnekow, Sandeep Rana
Publikováno v:
Mol Cell Biol
Epidermal growth factor receptor (EGFR) is a prototype receptor tyrosine kinase and an oncoprotein in many solid tumors. Cell surface display of EGFR is essential for cellular responses to its ligands. While postactivation endocytic trafficking of EG
Autor:
Ch. Zechel, Thomas Gronau, A. Pröfrock, Angelika Barnekow, A. Smith, Fritz Anders, I. M. Bird, P. A. Lane
Publikováno v:
Hereditary Malignant Melanoma ISBN: 9780429276514
Hereditary Malignant Melanoma
Hereditary Malignant Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2620e800cae532d0a2fbae1aff5777f1
https://doi.org/10.1201/9780429276514-8
https://doi.org/10.1201/9780429276514-8
Autor:
Nicole Hübel, Angelika Barnekow, Veerle Baekelandt, Evy Lobbestael, Mary W. McCaffrey, Amir R. Khan, Edith Ossendorf, Andrew J. Lindsay, Dieter Waschbüsch
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0208889 (2019)
PLoS ONE, Vol 14, Iss 1, p e0208889 (2019)
The Rab family of small GTPases regulate various aspects of cellular dynamics in eukaryotic cells. Membrane trafficking has emerged as central to the functions of leucine-rich repeat kinase 2 (LRRK2), which is associated with inherited and sporadic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5446e7145edaceaf141b070c0fc21e5a
https://lirias.kuleuven.be/handle/123456789/634845
https://lirias.kuleuven.be/handle/123456789/634845
Autor:
Angelika Barnekow, Goran Lakisic, Dieter Waschbüsch, Jan Hänisch, Debbie Hügging, Kai Schlüter, Sabine Kind, Moritz Anft, Theresia E. B. Stradal, Alexis Gautreau
Publikováno v:
European Journal of Cell Biology. 93:194-204
Junction-mediating and regulatory protein (JMY) was originally identified as a transcriptional co-factor in the p53-response to DNA damage. Aside from this nuclear function, recent years have uncovered an additional function of JMY, namely in cytoske
Autor:
Angelika Barnekow, Markus Borschbach, Winfried Dreckmann, Jonas Winkler, Dominik Heider, Andreas Held, Tuygun Bayro, Jessica Appelmann
Publikováno v:
Technology in Cancer Research & Treatment. 8:333-341
The prediction of essential biological features based on a given protein sequence is a challenging task in computational biology. To limit the amount of in vitro verification, the prediction of essential biological activities gives the opportunity to
Autor:
Amjad H. Talukder, Bramanandam Manavathi, Joachim Kremerskothen, Petra den Hollander, Rakesh Kumar, Shaohua Peng, Angelika Barnekow, Suresh K. Rayala, Chunying Song
Publikováno v:
Journal of Biological Chemistry. 281:19092-19099
Recently dynein light chain 1 (DLC1), a cytoskeleton signaling component, has been shown to interact with and transactivate estrogen receptor-alpha (ER), leading to increased expression of ER target genes and growth stimulation of breast cancer cells
Autor:
Angelika Barnekow, Konstantinos Bilbilis, Iskender Teber, Bruno Goud, Fumiko Nagano, Joachim Kremerskothen
Publikováno v:
Biological Chemistry. 386:671-677
The Rab6 GTPase regulates a retrograde transport route connecting endosomes and the endoplasmic reticulum (ER) via the Golgi apparatus. Recently it was shown that active (GTP-loaded) Rab6A regulates intracellular processing of the amyloid precursor p