Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Angelika B Riemer"'
Autor:
Iryna Dekhtiarenko, Robert B Ratts, Renata Blatnik, Lian N Lee, Sonja Fischer, Lisa Borkner, Jennifer D Oduro, Thomas F Marandu, Stephanie Hoppe, Zsolt Ruzsics, Julia K Sonnemann, Mandana Mansouri, Christine Meyer, Niels A W Lemmermann, Rafaela Holtappels, Ramon Arens, Paul Klenerman, Klaus Früh, Matthias J Reddehase, Angelika B Riemer, Luka Cicin-Sain
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006072 (2016)
Cytomegalovirus (CMV) elicits long-term T-cell immunity of unparalleled strength, which has allowed the development of highly protective CMV-based vaccine vectors. Counterintuitively, experimental vaccines encoding a single MHC-I restricted epitope o
Externí odkaz:
https://doaj.org/article/9a787b2030704af9add09bb205309a6b
Autor:
Marten Meyer, Christina Parpoulas, Titouan Barthélémy, Jonas P. Becker, Pornpimol Charoentong, Yanhong Lyu, Selina Börsig, Nadja Bulbuc, Claudia Tessmer, Lisa Weinacht, David Ibberson, Patrick Schmidt, Rüdiger Pipkorn, Stefan B. Eichmüller, Peter Steinberger, Katharina Lindner, Isabel Poschke, Michael Platten, Stefan Fröhling, Angelika B. Riemer, Jessica C. Hassel, Maria Paula Roberti, Dirk Jäger, Inka Zörnig, Frank Momburg
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Peptide-loaded MHC class I (pMHC-I) multimers have revolutionized our capabilities to monitor disease-associated T cell responses with high sensitivity and specificity. To improve the discovery of T cell receptors (TCR) targeting neoantigens of indiv
Externí odkaz:
https://doaj.org/article/2562f0907ae7489481331f6d349419cb
Autor:
Nitya Mohan, Kathrin Wellach, Ceren Özerdem, Nisha Veits, Jonas D. Förster, Sophia Foehr, Maria Bonsack, Angelika B. Riemer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Attempts to develop a therapeutic vaccine against human papillomavirus (HPV)-induced malignancies have mostly not been clinically successful to date. One reason may be the hypoxic microenvironment present in most tumors, including cervical cancer. Hy
Externí odkaz:
https://doaj.org/article/58fe8aa9c4544ae69deabc8310f54998
Autor:
Jonas P. Becker, Angelika B. Riemer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Presentation of tumor-specific or tumor-associated peptides by HLA class I molecules to CD8+ T cells is the foundation of epitope-centric cancer immunotherapies. While often in silico HLA binding predictions or in vitro immunogenicity assays are util
Externí odkaz:
https://doaj.org/article/2367829a6fdd4d37a6ec388d07d125e0
Autor:
Christoph Schifflers, Samantha Zottnick, Jonas D. Förster, Sebastian Kruse, Ruwen Yang, Hendrik Wiethoff, Matthias Bozza, Karin Hoppe-Seyler, Mathias Heikenwälder, Richard P. Harbottle, Carine Michiels, Angelika B. Riemer
Publikováno v:
Pathogens, Vol 12, Iss 2, p 188 (2023)
Head and neck squamous cell carcinomas (HNSCC) caused by infections with high-risk human papillomaviruses (HPV) are responsible for an increasing number of head and neck cancers, particularly in the oropharynx. Despite the significant biological diff
Externí odkaz:
https://doaj.org/article/348fbcb7b76447cfac696a7379748075
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Head and neck squamous cell carcinomas (HNSCC), emerging in the mucosa of the upper aerodigestive tract, are associated with either the classical risk factors, tobacco and alcohol consumption, or with infections with high-risk types of the human papi
Externí odkaz:
https://doaj.org/article/e16932090e6541209ddfc88e0cb18b7c
Autor:
Rachel Karchin, Kymberleigh A. Pagel, Valsamo Anagnostou, Victor E. Velculescu, Angelika B. Riemer, Maria Bonsack, Ashton Omdahl, Benjamin Kaminow, Dylan Hirsch, Lily Zheng, Collin Tokheim, I.K. Ashok Sivakumar, Justin Huang, Rohit Bhattacharya, Xiaoshan M. Shao
Computational prediction of binding between neoantigen peptides and major histocompatibility complex (MHC) proteins can be used to predict patient response to cancer immunotherapy. Current neoantigen predictors focus on in silico estimation of MHC bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c0778ecef7bdfa27d9fb04698e44af
https://doi.org/10.1158/2326-6066.c.6550177
https://doi.org/10.1158/2326-6066.c.6550177
Autor:
Angelika B. Riemer, Renata Blatnik, Eva C. Schitter, Marius D. Küpper, Christine Zeller, Diana Tichy, Jan Winter, Stephanie Hoppe, Maria Bonsack
This file contains the combined supplementary figures and tables. Table S1. Prediction methods used in this study. Table S2. In silico predicted and in vitro validated binding affinities of peptides derived from HPV16 E6 and E7 proteins for the HLA t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296dfababe10c1bccaf50603ac7a0d81
https://doi.org/10.1158/2326-6066.22542396.v1
https://doi.org/10.1158/2326-6066.22542396.v1
Autor:
Rachel Karchin, Kymberleigh A. Pagel, Valsamo Anagnostou, Victor E. Velculescu, Angelika B. Riemer, Maria Bonsack, Ashton Omdahl, Benjamin Kaminow, Dylan Hirsch, Lily Zheng, Collin Tokheim, I.K. Ashok Sivakumar, Justin Huang, Rohit Bhattacharya, Xiaoshan M. Shao
Supplemental Legend for Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5098637e5f1fcaf7e2cae9cd07ceb466
https://doi.org/10.1158/2326-6066.22543228
https://doi.org/10.1158/2326-6066.22543228
Autor:
Angelika B. Riemer, Renata Blatnik, Eva C. Schitter, Marius D. Küpper, Christine Zeller, Diana Tichy, Jan Winter, Stephanie Hoppe, Maria Bonsack
Knowing whether a protein can be processed and the resulting peptides presented by major histocompatibility complex (MHC) is highly important for immunotherapy design. MHC ligands can be predicted by in silico peptide–MHC class-I binding prediction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f931ad4de8dc0ba2ea44e7a9433317
https://doi.org/10.1158/2326-6066.c.6549906
https://doi.org/10.1158/2326-6066.c.6549906